MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Protein purification and separation can be done by all except |
| A. | Chromatography |
| B. | Centrifugation |
| C. | Electrophoresis |
| D. | Densitometry |
| Answer» E. | |
| 2. |
Glycogen phosphorylase co-enzyme associated with ? |
| A. | Thiamine pyrophosphate |
| B. | Tetrahydrofolate |
| C. | Flavin mononuleotide |
| D. | Pyridoxal phosphate |
| Answer» E. | |
| 3. |
In sickle cell anemia replacement is - |
| A. | Glu by val in b6 |
| B. | Valbglu in b6 |
| C. | 6A |
| D. | Hist val b8 |
| Answer» B. Valbglu in b6 | |
| 4. |
Peptide bond- |
| A. | Is single bond in character |
| B. | Is double bond in character |
| C. | Is partial double bond in character |
| D. | None of the above |
| Answer» D. None of the above | |
| 5. |
Movement of protein from nucleus to cytoplasm can be seen by |
| A. | FRAP |
| B. | FISH |
| C. | Electron microscopy |
| D. | Confocal microscopy |
| Answer» B. FISH | |
| 6. |
Refsum's disease is a rare neurological disorder caused by - |
| A. | Accumulation of glutamic acid |
| B. | Accumulation of glycine |
| C. | Accumulation of phytonic acid |
| D. | Accumulation of phenylalanine |
| Answer» D. Accumulation of phenylalanine | |
| 7. |
Apoprotein A is found in |
| A. | Chylomicrons |
| B. | VLDL |
| C. | HDL |
| D. | LDL |
| Answer» D. LDL | |
| 8. |
Which of these fatty acids is found exclusively in breast milk: |
| A. | Palmitic |
| B. | Docosahexanoic acid |
| C. | Linolaete |
| D. | Linolenic |
| Answer» C. Linolaete | |
| 9. |
Structurally heparin is a |
| A. | Homopolysaccharide |
| B. | Heteropolysaccharide |
| C. | Glycoprotein |
| D. | Mucoprotein |
| Answer» C. Glycoprotein | |
| 10. |
Which of the statements best characterize glucose? |
| A. | It usually exits in furanose form |
| B. | It is a ketose |
| C. | It forms part of the disaccharide sucrose |
| D. | It is oxidized to form sorbitol |
| Answer» D. It is oxidized to form sorbitol | |
| 11. |
In familial hypercholesterolemia there is deficiency of - |
| A. | LDL receptor |
| B. | Apo protein A |
| C. | Apo protein C |
| D. | Lipoprotein lipase |
| Answer» B. Apo protein A | |
| 12. |
Phospho-dephosphorylation of phosphofructokinase and fructose 1,6 biphosphate by fructose 2,6, Biphosphate regulation is seen in - |
| A. | Liver |
| B. | Bran |
| C. | RBC |
| D. | Adrenal Cortex |
| Answer» B. Bran | |
| 13. |
There are more than 300 variants of human hemoglobin gene.Among these only a few are fatal.Hence,the most important factor to be conserved in a protein for its function is the: |
| A. | Ligand binding residues |
| B. | Amino acid sequence |
| C. | Environment |
| D. | Structure |
| Answer» B. Amino acid sequence | |
| 14. |
True statement about DNA structure - |
| A. | All nucleotides are involved in linkage |
| B. | Antiparallel |
| C. | Bases are perpendicular to DNA |
| D. | All of the above |
| Answer» E. | |
| 15. |
Receptor mediated endocytosis is by - |
| A. | Clathrin |
| B. | Porine |
| C. | Cytocin |
| D. | Vimentin |
| Answer» B. Porine | |
| 16. |
Which of the following acts as co-enzymes and not as co-factors - |
| A. | Pyridoxine |
| B. | Biotin |
| C. | Thiamine |
| D. | All of the above |
| Answer» E. | |
| 17. |
A baby presents with refusal to feed,skin lesions,seizures,ketosis organic acids in urine with normal ammonia;likely diagnosis is: |
| A. | Multiple carboxylase deficiency |
| B. | Proprionic aciduria |
| C. | Urea cycle enzyme deficiency |
| D. | Maple syrup urine disease |
| Answer» B. Proprionic aciduria | |
| 18. |
Characteristics of glycoprotein - |
| A. | Protein linked with glycosidic |
| B. | Core protein |
| C. | Sugar residues are long in carbohydrate portion of glycoprotein |
| D. | All of the above |
| Answer» B. Core protein | |
| 19. |
Among the the following all are hydrophilic hormones that act on cytosolic receptors except one which is lipophilic hormone that acts on nuclear receptor : |
| A. | GH |
| B. | ACTH |
| C. | Thyroxine |
| D. | Epinephrine |
| Answer» D. Epinephrine | |
| 20. |
Eukaryotic plasma membraneis made up of all except: |
| A. | Triglycerides |
| B. | Carbohydrates |
| C. | Cholesterol |
| D. | Lecithin |
| Answer» B. Carbohydrates | |
| 21. |
Termination is caused by all except - |
| A. | Peptidyl transferase |
| B. | 48 s complex |
| C. | RF-1 |
| D. | UAA |
| Answer» C. RF-1 | |
| 22. |
NADPH is generated by the action of - |
| A. | Glucose 6 phosphate dehydrogenase |
| B. | Glucose 1 phosphate dehydrogenase |
| C. | Glucose 1.6 phosphate dehydrogenase |
| D. | All of the above |
| Answer» B. Glucose 1 phosphate dehydrogenase | |
| 23. |
Arachidonic acid is synthesized from ? |
| A. | Linolenic acid |
| B. | Linoleic acid |
| C. | Prostaglandins |
| D. | Oleic acid |
| Answer» C. Prostaglandins | |
| 24. |
Non functional enzymes are all except |
| A. | Acid phosphatase |
| B. | Alkaline phosphatase |
| C. | Gamma glutamyl transpeptidase |
| D. | Lipoprotein lipase |
| Answer» E. | |
| 25. |
What is the substrate for the only physiologically irreversible reaction in the Kreb's Citric acid cycle - |
| A. | Alpha ketoglutarate |
| B. | Citrate |
| C. | Malate |
| D. | Succinate |
| Answer» B. Citrate | |
| 26. |
Transfer of genetic material in 1 meiotic division between 2 non-homologous chromosomes - |
| A. | Invention |
| B. | Isochromose |
| C. | Translocation |
| D. | Non-disjunction |
| Answer» D. Non-disjunction | |
| 27. |
Cystinuria is associated with excretion of which A.A in urine - |
| A. | Cystine, ornithine, lysine and arginine |
| B. | Cystine, ornithine, lysine and arginine |
| C. | Cystine, lysine, Tyrosine and alanine |
| D. | Cystine, lysine, ornithine and alanine |
| Answer» C. Cystine, lysine, Tyrosine and alanine | |
| 28. |
What is true regarding medium chain fatty acids ? |
| A. | Do not require pancreatic lipase |
| B. | Diffuse directly into portal circulation |
| C. | Not deposited in adipose tissue |
| D. | All of the avove |
| Answer» E. | |
| 29. |
Glycosyl transferase of O-glycosylation is found in - |
| A. | SER |
| B. | RER |
| C. | Lysosome |
| D. | Golgi |
| Answer» E. | |
| 30. |
Niemann's pick disease is due to deficiency of which enzyme ? |
| A. | Sphingomyelinase |
| B. | Hexosaminidase-A |
| C. | Aryl suplhatase |
| D. | Galactosidase-A |
| Answer» B. Hexosaminidase-A | |
| 31. |
Energy required for maintenance of body functions of a person weighting 40 kgs is - |
| A. | 2000 kilocalories |
| B. | 2500 kilocalories |
| C. | 1000 kilocalories |
| D. | 15000 kilocalories |
| Answer» D. 15000 kilocalories | |
| 32. |
NADPH is utilized in - |
| A. | Gluconeogenesis |
| B. | Glycogenesis |
| C. | Fatty acid synthesis |
| D. | HMP shunt pathway |
| Answer» D. HMP shunt pathway | |
| 33. |
Which one of the following can be a homologous substitution for isoleucine in a protein sequence? |
| A. | Aspartic acid |
| B. | Methionine |
| C. | Arginine |
| D. | Valine |
| Answer» E. | |
| 34. |
All of the following enzymes are regulated by calcium or calmodulin,except: |
| A. | Glycogen synthase |
| B. | Hexokinase |
| C. | Adenylate cyclase |
| D. | Guanylyl cyclase |
| Answer» C. Adenylate cyclase | |
| 35. |
Which of the following is luminous |
| A. | Porphyrin |
| B. | Zymogen |
| C. | Chromatin |
| D. | Albumin |
| Answer» B. Zymogen | |
| 36. |
In hemoglobin,iron is bound to |
| A. | Histidine |
| B. | Leucine |
| C. | Isoleucine |
| D. | Valine |
| Answer» B. Leucine | |
| 37. |
Cyanide causes inhibition of transfer of reducing equivalents in the respiratory chain in the stage: |
| A. | Between NADH and coenzyme Q |
| B. | Between cytochrome b and cytochrome |
| C. | Between cytochrome oxidase and molecular O2 |
| D. | Between coenzyme Q and cytochrome |
| Answer» D. Between coenzyme Q and cytochrome | |
| 38. |
Molecular size is assesed by - |
| A. | Absorption mass spectroscoy |
| B. | Sidimentation |
| C. | Salting out |
| D. | Liophilization |
| Answer» B. Sidimentation | |
| 39. |
True about MHC - |
| A. | Transplantation reaction |
| B. | Autoimmune disease |
| C. | Involved in T-cell function |
| D. | All of the above |
| Answer» E. | |
| 40. |
Which technique is based on Molecular size? |
| A. | Gel electrophoresis |
| B. | Gel filtration |
| C. | Chromatography |
| D. | Isoelectric focussing |
| Answer» C. Chromatography | |
| 41. |
The enzyme not present in the skeletal muscles - |
| A. | Phosphofructokinase |
| B. | Glucose 6 phosphatase |
| C. | Creatinine phosphokinase |
| D. | Hexokinase |
| Answer» C. Creatinine phosphokinase | |
| 42. |
Vitamin B12 deficiency has A/E - |
| A. | Decreased methyl malonyl CoA |
| B. | Folate trap |
| C. | Megaloblastic anemia |
| D. | SACD |
| Answer» B. Folate trap | |
| 43. |
What is metabolised like xenobiotics - |
| A. | Myoglobin |
| B. | Bilirubin |
| C. | Biliverdin |
| D. | Haemoglobin |
| Answer» C. Biliverdin | |
| 44. |
All steps of N-glycosylation occur in ER except - |
| A. | Protein - oligosacharide transferase |
| B. | Final trimming |
| C. | Dolichol synthesis |
| D. | Glycosyl transferase |
| Answer» C. Dolichol synthesis | |
| 45. |
A child presents with hepatomegaly and bilateral lenticular opacities.Deficiency of which of the following enzymes will not cause such features. |
| A. | Galactose-1-phosphate uridyl transferase |
| B. | UDP-galactose-4 epimerase |
| C. | Galactosekinase |
| D. | Lactase |
| Answer» E. | |
| 46. |
Auto oxidation is seen in ? |
| A. | Cholesterol |
| B. | Arachidonic acid |
| C. | Steric acid |
| D. | Palmitic acid |
| Answer» C. Steric acid | |
| 47. |
Transition mutation of GATCCT is - |
| A. | GABCCT |
| B. | GrUGGT |
| C. | GGTCCT |
| D. | GTTCCT |
| Answer» D. GTTCCT | |
| 48. |
Cobalt forms a component of which vitamin |
| A. | Biotin |
| B. | Vitamin B12 |
| C. | Vitamin A |
| D. | Tocopherol |
| Answer» C. Vitamin A | |
| 49. |
In transcription anticodon is seen in - |
| A. | r-RNA |
| B. | DNA |
| C. | t-RNA |
| D. | m-RNA |
| Answer» D. m-RNA | |
| 50. |
During sexual differentiation in males - |
| A. | Leydig cells produce mullerian inhibiting substance |
| B. | Primitive gonads differentiate into testis due to the presence of SRY gene |
| C. | Androgen binding protein is responsible for the development of male external genitalia |
| D. | Wolffian duct regresses |
| Answer» C. Androgen binding protein is responsible for the development of male external genitalia | |