MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Molecular change in Lysosomes storage disorder is - |
| A. | Increase synthesis of some substrates |
| B. | Defective fusion of lysosomes and phagosomes |
| C. | Membrane defect of lysosomes |
| D. | Mutation of genes encoding lysosomal hydrolase |
| Answer» E. | |
| 2. |
Amino acid used in Carnitine synthesis is ? |
| A. | Alamine |
| B. | Lysine |
| C. | Arginine |
| D. | Tyrosine |
| Answer» C. Arginine | |
| 3. |
Suicidal Enzyme - |
| A. | Cyclooxygenase |
| B. | Lipooxygenans |
| C. | 5-nucleotidase |
| D. | Thrombaxane synthase |
| Answer» B. Lipooxygenans | |
| 4. |
In CRP, the C stands for - |
| A. | Chondoitin sulfate |
| B. | C polysaccharide of streptococcus |
| C. | Canavallin A |
| D. | Cellular |
| Answer» C. Canavallin A | |
| 5. |
Compound that joints glycolysis with glycogenesis and glycogenolysis |
| A. | Glucose 1 PO4 |
| B. | Glucose 6 PO4 |
| C. | Fructose 1,6 bi phosphate |
| D. | Glucose 1,6 bi phosphate |
| Answer» C. Fructose 1,6 bi phosphate | |
| 6. |
In a human genome project, scientist notices that one strand of the DNA molecule contains 20 thymine(T), 25 cytosine(C), 30 guanine(G), and 22 adenine(A) residues. How many of each of the bases are found in the complete double stranded molecule ? |
| A. | T=44, C=60, G=50, A= 40 |
| B. | T=22, C=30, G=25, A= 20 |
| C. | T=40, C=50, G=60, A= 44 |
| D. | T=42, C=55, G=55, A= 42 |
| Answer» D. T=42, C=55, G=55, A= 42 | |
| 7. |
Splicing activity is a function of : |
| A. | snRNA |
| B. | mRNA |
| C. | rRNA |
| D. | tRNA |
| Answer» B. mRNA | |
| 8. |
Which of the following hormones acts through intracellular receptor: |
| A. | Thyroxine |
| B. | Insulin |
| C. | Glucagon |
| D. | Adrenaline |
| Answer» B. Insulin | |
| 9. |
The amino acids producing ammonia in kidney is - |
| A. | Methionine |
| B. | Glycine |
| C. | Glutamine |
| D. | Alanine |
| Answer» D. Alanine | |
| 10. |
True regarding aminoacyl t-RNA synthetase is A/E - |
| A. | Implement genetic code |
| B. | Isoaccepting t-RNA |
| C. | Editing function |
| D. | Attachment of amino group to 5' end |
| Answer» E. | |
| 11. |
Increased risk of Myocardial infarction is associated with which amino acid |
| A. | Methionine |
| B. | Homocystine |
| C. | Ornithine |
| D. | Valine |
| Answer» C. Ornithine | |
| 12. |
Heamoglobin unlike myoglobin shows - |
| A. | Co-operative effect of combine O2 |
| B. | Parabolic curve of oxygen association |
| C. | Hill's coefficient of 1 |
| D. | Cooperative index of 81 |
| Answer» B. Parabolic curve of oxygen association | |
| 13. |
Which form of DNA is predominantly seen |
| A. | A |
| B. | C |
| C. | B |
| D. | Z |
| Answer» D. Z | |
| 14. |
CAP in Lac operon is an example of: |
| A. | Positive regulator |
| B. | Negative regulator |
| C. | Constitutive expression |
| D. | Attenuation |
| Answer» B. Negative regulator | |
| 15. |
Rich source of IgG is - |
| A. | Visceral peritoneum |
| B. | Stomach |
| C. | Large intestine |
| D. | Small intestine |
| Answer» E. | |
| 16. |
The buffering capacity of a buffer is maximum at pH equal to |
| A. | pKa |
| B. | 0.5 pKa |
| C. | 2pKa |
| D. | pKa+1 |
| Answer» B. 0.5 pKa | |
| 17. |
A mother complains that baby's urine turns black on standing likely diagnosis is: |
| A. | Phenyl ketonuria |
| B. | Maple syrup urine disease |
| C. | Alkaptonuria |
| D. | None of the above |
| Answer» D. None of the above | |
| 18. |
Random arrangement of molecule in - |
| A. | Crystalliazation |
| B. | Precipitation |
| C. | Denaturation |
| D. | High solubility |
| Answer» D. High solubility | |
| 19. |
Amber codon refers to - |
| A. | Stop codon |
| B. | Mutant codon |
| C. | Codon for more than one amino acids |
| D. | Initiating codon |
| Answer» B. Mutant codon | |
| 20. |
For PCR which of the following is not required - |
| A. | Primer |
| B. | Radiolabelled DNA probe |
| C. | Taq polymerase |
| D. | d-NTP |
| Answer» C. Taq polymerase | |
| 21. |
True about Sickle cell disease are all, except |
| A. | Sticky patch is generated as a result of replacement of a non polar residue with a polar residue |
| B. | Single nucleotide change results in change of Glutamine to Valine |
| C. | RFLP results from a single base change |
| D. | HbS confers resistance against malaria in heterozygotes |
| Answer» B. Single nucleotide change results in change of Glutamine to Valine | |
| 22. |
Triplex DNA is due to |
| A. | Large no. of guanosine repeats |
| B. | Polypyramidine tracts |
| C. | Hoogsteen pairing |
| D. | Plaindromic sequences |
| Answer» D. Plaindromic sequences | |
| 23. |
The primary role of chaperones is to help in: |
| A. | Protein denaturation |
| B. | Protein folding |
| C. | Protein synthesis |
| D. | Protein degradation |
| Answer» C. Protein synthesis | |
| 24. |
The hormone using an enzyme receptor for its action: |
| A. | Oestrogen |
| B. | Thyroxine |
| C. | Insulin |
| D. | Steroid |
| Answer» D. Steroid | |
| 25. |
Which of the following statement about thiamine is true? |
| A. | Its co-enzyme function is done by thiamine monophosphate |
| B. | It is co-enzyme for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase |
| C. | It is a co-enzyme of lactate dehydrogenase |
| D. | Its deficiency is associated with scurvy |
| Answer» C. It is a co-enzyme of lactate dehydrogenase | |
| 26. |
Not a dietary source of vit. B 12 - |
| A. | Fish |
| B. | Meat |
| C. | Soyabean |
| D. | Liver |
| Answer» D. Liver | |
| 27. |
UV light damage to the DNA leads to - |
| A. | DNA hydrolysis |
| B. | Double stranded breaks |
| C. | Formation of pyrimidine dimmers |
| D. | No damage to DNA |
| Answer» D. No damage to DNA | |
| 28. |
Which of the following has highest electrophoretic mobility and least lipid content - |
| A. | LDL |
| B. | VLDL |
| C. | Chylomicrons |
| D. | HDL |
| Answer» D. HDL | |
| 29. |
True about gaucher disease - |
| A. | Due to deficiency of enzyme Beta-Gluco-cerebrosidase |
| B. | Deposition of glucosylceramide |
| C. | PAS staining positive |
| D. | All of the above |
| Answer» E. | |
| 30. |
Enzymes used in DNA research programme are except - |
| A. | Polymerase |
| B. | Exonuclease |
| C. | Nuclease |
| D. | None of the above |
| Answer» E. | |
| 31. |
Cofactor involve in sulphur containing amino acid metabolism is ? |
| A. | Folic acid |
| B. | Biotin |
| C. | Vitamin B1 |
| D. | Vitamin B12 |
| Answer» E. | |
| 32. |
Which of the following enzymes is obtained from Thermophilus aquaticus bacterium which is heat stable and used in PCR at high temperature ? |
| A. | DNA polymerase III |
| B. | Endonuclease |
| C. | Taq polymerase |
| D. | DNA gyrase |
| Answer» D. DNA gyrase | |
| 33. |
Vitamin K required for - |
| A. | Transmination |
| B. | Carboxylation |
| C. | Hydroxylation |
| D. | Chelation |
| Answer» C. Hydroxylation | |
| 34. |
Ribosome has following enzymatic activity |
| A. | Aminoacyl tRNA synthetase |
| B. | GTPase |
| C. | Peptidyl transferase |
| D. | Peptidase |
| Answer» D. Peptidase | |
| 35. |
Leucine is a aminoacid with a: |
| A. | Negatively charged side chain |
| B. | Positively charged side chain |
| C. | Nonpolar side chain |
| D. | Polar side chain |
| Answer» D. Polar side chain | |
| 36. |
Which of the following is seen in association with membrane raft |
| A. | GTP associated receptor |
| B. | Mannose binding protein |
| C. | - |
| D. | GPI anchored protein |
| Answer» E. | |
| 37. |
Which of the following is/are feature of polymerase used in recombinant synthesis - |
| A. | Thermostable |
| B. | Does not require primer |
| C. | Unusually active |
| D. | All of the above |
| Answer» B. Does not require primer | |
| 38. |
Regarding proteoglycans,false is: |
| A. | Chondroitin sulfate is a Proteoglycan |
| B. | They hold less amount of water |
| C. | They are made up of sugar and aminoacids |
| D. | They carry charge |
| Answer» C. They are made up of sugar and aminoacids | |
| 39. |
Action of 'Telomerase' is - |
| A. | Longetivity of cell- Ageing |
| B. | DNA repair |
| C. | None |
| D. | Breakdown of telmore |
| Answer» B. DNA repair | |
| 40. |
Glycolysis occurs in - |
| A. | Nucleus |
| B. | Lysosomes |
| C. | Cytosol |
| D. | Mitochondria |
| Answer» D. Mitochondria | |
| 41. |
The collagen triple helix structure is not found in: |
| A. | Lumen of endoplasmic reticulum |
| B. | Intracellular vescicles |
| C. | Cytoplasm |
| D. | Golgi apparatus |
| Answer» D. Golgi apparatus | |
| 42. |
Sphingomyelinase Deficiency is seen in: |
| A. | Tay sach's disease |
| B. | Krabbe's disease |
| C. | Niemann - Pick disease |
| D. | Farber's disease |
| Answer» D. Farber's disease | |
| 43. |
Inhibitors of DNA synthesis - |
| A. | Chloramphenicol |
| B. | Actinomycin |
| C. | Penicillin |
| D. | Polymyxin |
| Answer» C. Penicillin | |
| 44. |
Regarding HMP shunt all of the following are true except: |
| A. | Occurs in the cytosol |
| B. | No ATP is produced in the cycle |
| C. | It is active in Adipose tissue,Liver and Gonads. |
| D. | The oxidative phase generates NADPH and the Non oxidative phase generates pyruvate. |
| Answer» E. | |
| 45. |
All of the following assays are used for estimation of total serum protein,Except: |
| A. | Lowry's |
| B. | Bromocresol green |
| C. | Biuret |
| D. | Bradford |
| Answer» C. Biuret | |
| 46. |
True about coding strand of DNA - |
| A. | Minus strand |
| B. | Template strand |
| C. | Runs at 3'--5' direction |
| D. | Runs at 5--3' direction |
| Answer» E. | |
| 47. |
Reverse transcriptase forms: |
| A. | DNA to RNA |
| B. | RNA to DNA |
| C. | DNA to DNA |
| D. | DNA to protein |
| Answer» C. DNA to DNA | |
| 48. |
Reperfusion injury is caused by: |
| A. | Superoxide ion |
| B. | Vitamin E |
| C. | Magnesium ion |
| D. | Calcium ion |
| Answer» B. Vitamin E | |
| 49. |
Cellular oxidation is inhibited by: |
| A. | Chocolate |
| B. | Carbonated beverages |
| C. | Cyanide |
| D. | Carbon dioxide |
| Answer» D. Carbon dioxide | |
| 50. |
Histone has post - translational by all/except - |
| A. | Acylation |
| B. | Methylation |
| C. | Phosphorylation |
| D. | Glycosylation |
| Answer» E. | |