MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which end product of citric acid cycle is used in detoxification of ammonia in brain - |
| A. | Alphaketoglutarate |
| B. | Oxaloacetate |
| C. | Citrate |
| D. | Succinate |
| Answer» B. Oxaloacetate | |
| 2. |
Maximum content of triglycerides are found in - |
| A. | HDL |
| B. | LDL |
| C. | Chylomicrons |
| D. | VLDL |
| Answer» D. VLDL | |
| 3. |
True about DNA methylation - |
| A. | Alters gene expression |
| B. | Genetic code remains intact |
| C. | Role in carcinogenesis |
| D. | All of the above |
| Answer» E. | |
| 4. |
What is not true about gout - |
| A. | Development of arthritis correlates with level of serum uric acid |
| B. | Uric acid crystals are best seen by polarising light microscope |
| C. | Abrupt increase in serum urate levels is more common a cause for acute gout than on abrupt fall in urate levels |
| D. | Patient may be asymptomatic with high serum uric acid for years |
| Answer» D. Patient may be asymptomatic with high serum uric acid for years | |
| 5. |
Sources of the nitrogen in urea cycle are: |
| A. | Arginine and ammonia |
| B. | Uric acid |
| C. | Aspartate and ammonia |
| D. | Glutamate and ammonia |
| Answer» D. Glutamate and ammonia | |
| 6. |
Selenium is co-factor for : |
| A. | Glutathione synthetase |
| B. | Glutathione dehydrogenase |
| C. | Glutathione peroxidase |
| D. | Glutathione reductase |
| Answer» D. Glutathione reductase | |
| 7. |
Energy source used by brain in later days of Starvation is |
| A. | Glucose |
| B. | Ketone bodies |
| C. | Glycogen |
| D. | Fatty acids |
| Answer» C. Glycogen | |
| 8. |
The enzyme lipoprotein lipase is located at the endothelial layer of capillaries of the following tissues except - |
| A. | Adipose tissue |
| B. | Liver |
| C. | Heart |
| D. | Muscles |
| Answer» C. Heart | |
| 9. |
Histone has post - translational modification by all/except - |
| A. | Phosphorylation |
| B. | Glycosylation |
| C. | Acylation |
| D. | Methylation |
| Answer» C. Acylation | |
| 10. |
What is the composition of lugols solution ? |
| A. | 4% iodine and 10% potassium iodine |
| B. | 5% iodine and 10% potassium iodine |
| C. | 2.5% iodine and 5% potassium iodine |
| D. | 10% iodine and 6% potassium iodine |
| Answer» C. 2.5% iodine and 5% potassium iodine | |
| 11. |
DNA microarrays allow detection of Gene mutations using ? |
| A. | Polymerase Chain Reaction |
| B. | Cloning |
| C. | Southern Blotting |
| D. | Hybridization |
| Answer» E. | |
| 12. |
False statement is - |
| A. | IP TG is inducer but not subtrate |
| B. | Regulator gene is inducible |
| C. | Repressor binds operator gene |
| D. | Regulator genes produces repressor subunits |
| Answer» C. Repressor binds operator gene | |
| 13. |
DNA fingerprinting is based on possessing in DNA of - |
| A. | Variable Number Tandem Repeats |
| B. | Constant Tandem Repeat |
| C. | Exon |
| D. | Non-repeatative sequence |
| Answer» B. Constant Tandem Repeat | |
| 14. |
Which one is nonsense codon - |
| A. | UUA |
| B. | UAG |
| C. | UAU |
| D. | All of the above |
| Answer» C. UAU | |
| 15. |
Lp(a)is structurally similar to |
| A. | Plasminogen |
| B. | Apo B 48 |
| C. | LDL |
| D. | Apo B 100 |
| Answer» B. Apo B 48 | |
| 16. |
Blood level of this ketone body will be the maximum during ketosis |
| A. | Alpha ketoglutarate |
| B. | Beta hydroxy butyrate |
| C. | Acetoacetate |
| D. | Acetone |
| Answer» C. Acetoacetate | |
| 17. |
Which test uses oligator with single base pair substitution |
| A. | RFLP |
| B. | PCR |
| C. | None |
| D. | Error coded mutation analysis |
| Answer» B. PCR | |
| 18. |
Vitamin B12 is needed in: |
| A. | Kreb's cycle |
| B. | Fatty acid synthesis |
| C. | Pyruvate dehydrogenase |
| D. | All of the above |
| Answer» B. Fatty acid synthesis | |
| 19. |
Bita oxidation of palmitic acid yields - |
| A. | 129 ATP net |
| B. | 3 acetyl CoA |
| C. | 16 Acetyl CoA |
| D. | 131 ATP net |
| Answer» B. 3 acetyl CoA | |
| 20. |
Rothera's test used for detection of |
| A. | Fatty Acid |
| B. | Ketones |
| C. | Proteins |
| D. | Glucose |
| Answer» C. Proteins | |
| 21. |
Which of the following compounds can not be converted to glucose ? |
| A. | Lactate |
| B. | Glycerol |
| C. | Alpha ketoglutarate |
| D. | Acetyl CoA |
| Answer» E. | |
| 22. |
Non-Essential amino acid is - |
| A. | Lysine |
| B. | Threonine |
| C. | Tyrosine |
| D. | Phenylalanine |
| Answer» D. Phenylalanine | |
| 23. |
Rate limiting enzymes in the synthesis of cholesterol is - |
| A. | Acetyl CoA synthetase |
| B. | Acetyl-CoA caboxylase |
| C. | HMG CoA reductase |
| D. | HMG CoA synthetase |
| Answer» D. HMG CoA synthetase | |
| 24. |
Abzyme is a/an - |
| A. | Abnormal enzyme |
| B. | Antibody with a catalytic activity |
| C. | Isoenzyme |
| D. | Allosteric enzyme |
| Answer» C. Isoenzyme | |
| 25. |
Amino is detoxified in brain by - |
| A. | Glutamine |
| B. | Uric acid |
| C. | Urea |
| D. | Creatinine |
| Answer» B. Uric acid | |
| 26. |
Which of the following liver enzymes is predominantly mitochondrial |
| A. | GGT |
| B. | 5 Nucleotidase |
| C. | SGOT (AST) |
| D. | SGPT(ALT) |
| Answer» D. SGPT(ALT) | |
| 27. |
Menadione is analog of ? |
| A. | Vitamin K |
| B. | Vitamin A |
| C. | Vitamin D |
| D. | Vitamin C |
| Answer» B. Vitamin A | |
| 28. |
Enzyme regulated by phosphorylation - |
| A. | Citrate lyase |
| B. | Glycogen synthetase |
| C. | Pyruvate dehydrogenase |
| D. | All of the above |
| Answer» E. | |
| 29. |
Allosteric inhibition with ATP affects |
| A. | Phosphofructokinase |
| B. | G-PD |
| C. | Phospho-eno-pyruvate |
| D. | Pyruvate Kinase |
| Answer» B. G-PD | |
| 30. |
PFK is allosterically activated by ? |
| A. | Fructose 1, 6 bisphosphate |
| B. | Fructose 2, 6 bisphosphate |
| C. | Phosphoenolpyruvate |
| D. | Pyruvate |
| Answer» C. Phosphoenolpyruvate | |
| 31. |
True statements about PCR - |
| A. | Protein amplification |
| B. | DNA amplification |
| C. | Same as western blot test |
| D. | All of the above |
| Answer» C. Same as western blot test | |
| 32. |
Nonsense codons bring about - |
| A. | Initiation of protein synthesis |
| B. | Termination of protein synthesis |
| C. | Elongation of polypeptide chain |
| D. | Pre-translational modificastion of protein |
| Answer» C. Elongation of polypeptide chain | |
| 33. |
The most important carrier of cholesterol in plasma is: |
| A. | VLDL |
| B. | LDL |
| C. | Chylomicrons |
| D. | HDL |
| Answer» C. Chylomicrons | |
| 34. |
True about revesible non-competitive inhibitors - |
| A. | Not affec Vmax |
| B. | Lower km |
| C. | Not affect km |
| D. | All of the above |
| Answer» D. All of the above | |
| 35. |
Metabolites in HMP shunt are all except |
| A. | Glycerol-3 phosphate |
| B. | Sedoheptulose -7 phosphate |
| C. | Glyceraldehyde-3 phosphate |
| D. | Xylulose-5 phosphate |
| Answer» B. Sedoheptulose -7 phosphate | |
| 36. |
Mechanism of action of Nitric oxide is through: |
| A. | Ca++ |
| B. | Tyrosine |
| C. | cGMP |
| D. | cAMP |
| Answer» D. cAMP | |
| 37. |
At physiological pH, the carboxy-terminal of a peptide is - |
| A. | Positively charged |
| B. | Negatively charged |
| C. | Neural |
| D. | Infinitely charged |
| Answer» C. Neural | |
| 38. |
Malate shuttle is important in - |
| A. | Glycogenolysis |
| B. | Glycolysis |
| C. | Gluconeogenesis |
| D. | HMP shunt |
| Answer» C. Gluconeogenesis | |
| 39. |
Beta-oxidation of odd-chain fatty acids produces: |
| A. | Propionyl CoA |
| B. | Succinyl CoA |
| C. | Malonyl CoA |
| D. | Acetyl CoA |
| Answer» B. Succinyl CoA | |
| 40. |
NADPH is produced from all except: |
| A. | Cytosolic Isocitrate dehydrogenase |
| B. | Succinate dehydrogenase |
| C. | HMP shunt |
| D. | 6-Phosphogluconate dehydrogenase |
| Answer» C. HMP shunt | |
| 41. |
Transfer of an amino group from an amino acid to an Alpha-keto acid is done by: |
| A. | Transketolases |
| B. | Deaminases |
| C. | Transaminases |
| D. | Oxidases |
| Answer» D. Oxidases | |
| 42. |
The following methods can be used to detect the point mutation in the beta-globin gene that causes sickle cell anemia,except: |
| A. | DNA sequencing |
| B. | Northern blot analysis |
| C. | Polymerase chain reaction with allele-specific oligonucleotide hybridization |
| D. | Southern blot analysis |
| Answer» C. Polymerase chain reaction with allele-specific oligonucleotide hybridization | |
| 43. |
Enzyme deficiency seen in genetic disease like - |
| A. | Wilson's disease |
| B. | Family hypercholesterolemia |
| C. | Gaucher's disease |
| D. | Cystic Fibrosis |
| Answer» D. Cystic Fibrosis | |
| 44. |
Which of the following is a non-essential metal/mineral? |
| A. | Iron |
| B. | Lead |
| C. | Sodium |
| D. | Manganese |
| Answer» C. Sodium | |
| 45. |
True about gene library - |
| A. | Computer base with all gene knowledge |
| B. | DNA Nucleotide or fragment |
| C. | Also known as chromosome |
| D. | Library that contains books of gene |
| Answer» C. Also known as chromosome | |
| 46. |
Aromatic amino acids are - |
| A. | Tryptophan |
| B. | Tyrosine |
| C. | Phenylalanine |
| D. | All of the above |
| Answer» E. | |
| 47. |
Which of following substance binds to CoA and condense oxaloacetate to inhibit the TCA cycle: |
| A. | Arsenite |
| B. | Malonate |
| C. | Fumarate |
| D. | Fluoroacetate |
| Answer» E. | |
| 48. |
Vitamin B12 is absorbed in the |
| A. | Stomach |
| B. | Duodenum |
| C. | Ileum |
| D. | Colon |
| Answer» D. Colon | |
| 49. |
Poly(A) tail on translation will give rise to - |
| A. | Polyglycine |
| B. | Polylysine |
| C. | Polyalanine |
| D. | Polyproline |
| Answer» C. Polyalanine | |
| 50. |
True statement about Gkucokinase is/are - |
| A. | Km value is higher than normal blood sugar |
| B. | Found in liver |
| C. | Glucose inter into cells through GLUT-2 |
| D. | All of the above |
| Answer» E. | |