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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Creatinine is formed from - |
| A. | Leucine |
| B. | Histamine |
| C. | Arginine |
| D. | Lysine |
| Answer» D. Lysine | |
| 2. |
Stability of the toxoid in snake's venom is due to - |
| A. | Ionic bonds |
| B. | Van Dar Wall's bond |
| C. | Disulfide bonds |
| D. | Hydrogen bonds |
| Answer» D. Hydrogen bonds | |
| 3. |
The substance present in the gall bladder stones or the kidney stones can be best identified by the following techniques: |
| A. | Nuclear magnetic resonance |
| B. | X-ray diffraction |
| C. | Fluorescence spectroscopy |
| D. | Electron microscopy |
| Answer» C. Fluorescence spectroscopy | |
| 4. |
Which organ does not utilise ketone bodies - |
| A. | Liver |
| B. | Brain |
| C. | Skeletal muscles |
| D. | Cardiac muscles |
| Answer» B. Brain | |
| 5. |
Carbon atoms added in FA synthesis - |
| A. | 4 in Ist cycle and 2 in IInd cycle |
| B. | 2 in Ist cycle and 4 in IInd cycle |
| C. | 4 in Ist cycle and 4 in IInd cycle |
| D. | 2 in Ist cycle and 2 in IInd cycle |
| Answer» B. 2 in Ist cycle and 4 in IInd cycle | |
| 6. |
Sickling in 'HbS' disease is primarily caused by |
| A. | Altered Function |
| B. | Altered O2 binding capacity |
| C. | Decreased Solubility |
| D. | Decreased Stability |
| Answer» D. Decreased Stability | |
| 7. |
In starvation, bran utilizes glucose peferentially but not in the liver because - |
| A. | Low km value of hexokinase |
| B. | Low km glucokinase |
| C. | High blood flow |
| D. | All of the above |
| Answer» B. Low km glucokinase | |
| 8. |
Father to son inheritance is never seen in case of - |
| A. | Autosomal ressive inheritance |
| B. | Autosomal dominant inheritance |
| C. | Multifactorial inheritance |
| D. | X- linked recessive inheritance |
| Answer» E. | |
| 9. |
The amino acid that lacks chirality - |
| A. | Lysine |
| B. | Leucine |
| C. | Histidine |
| D. | Glycine |
| Answer» E. | |
| 10. |
End product purine metabolism is non-primate mammals is - |
| A. | Urea |
| B. | Allantoin |
| C. | Uric acid |
| D. | Ammonia |
| Answer» C. Uric acid | |
| 11. |
The activity of the following enzyme is affected by biotin deficiency: |
| A. | Oxidase |
| B. | Carboxylase |
| C. | Transketolase |
| D. | Dehydrogenase |
| Answer» C. Transketolase | |
| 12. |
Replication and transcription are similar processes in mechanistic terms because both: |
| A. | Use RNA primers for initiation |
| B. | Use deoxyribonucleotides as precursors |
| C. | Are semi conserved events |
| D. | Involve phosphodiester bond formation with elongation occuring in the 5' - 3' direction |
| Answer» E. | |
| 13. |
A newborn infant refuses breast milk since the 2nd day of birth,vomits on force-feeding but accepts glucose-water,develops diarrhea on the third day,by 5th day she is jaundiced with liver enlargement and eyes show signs of cataract.Urinary reducing sugar was positive but blood glucose estimated by glucose oxidation method was found low.The most likely cause is deficiency of: |
| A. | Galactose-1-phosphate uridyl transferase |
| B. | Beta galactosidase |
| C. | Glucose-6-phosphatase |
| D. | Galactokinase |
| Answer» B. Beta galactosidase | |
| 14. |
Most commonly occurring amino acid in the collagen structures is - |
| A. | Serine |
| B. | Glycine |
| C. | Hydroxy proline |
| D. | Proline |
| Answer» C. Hydroxy proline | |
| 15. |
Monoprotic acid are - |
| A. | Formic acid |
| B. | Acetic acid |
| C. | Nitric acid |
| D. | All of the above |
| Answer» E. | |
| 16. |
Gaucher's disease in due to deficiency of enzyme: |
| A. | Beta Glucosidase |
| B. | Sphingomyelinase |
| C. | Beta Galactosidase |
| D. | Hexosaminidase-A |
| Answer» B. Sphingomyelinase | |
| 17. |
Which of the following enzymes is involved in neoglucogenesis all except - |
| A. | Fructose 1,6-biphosphatase |
| B. | Phosphoglycerate kinase |
| C. | Isomerase |
| D. | Phosphoglucomutase |
| Answer» E. | |
| 18. |
In chromatography mass movements of the substances is due to - |
| A. | Paper chromatography |
| B. | Osmosis |
| C. | Diffusion |
| D. | Electrophoresis |
| Answer» D. Electrophoresis | |
| 19. |
Hydrophobic aminoacids are - |
| A. | Methione |
| B. | Tyrosine |
| C. | Isoleucine |
| D. | All of the above |
| Answer» E. | |
| 20. |
5' TTACGTAC-3' after transcription what will be the RNA - |
| A. | 5' CATGCATT-3 |
| B. | 5'-GUACGUAA-3' |
| C. | 5- TTACGTAC-3' |
| D. | 3' -TTACGTAC-5' |
| Answer» C. 5- TTACGTAC-3' | |
| 21. |
Normal role of Micro RNA is: |
| A. | Initiation of Translation |
| B. | DNA conformational change |
| C. | Gene Regulation |
| D. | RNA splicing |
| Answer» D. RNA splicing | |
| 22. |
True regarding conversion of deoxyhemoglobin to oxyhemoglobin is: |
| A. | Binding of O2causes release of H+ |
| B. | One mole of deoxyhemoglobin binds two moles of 2,3DPG |
| C. | pH of blood has no affect on the binding of O2 |
| D. | Binding of O2causes increased binding of 2,3DPG |
| Answer» B. One mole of deoxyhemoglobin binds two moles of 2,3DPG | |
| 23. |
During heme synthesis, which enzyme is responsible for conversion of Coproporphyrinogen III to Protoporphyrinogen III ? |
| A. | Protoporphyrinogen oxidase |
| B. | Coproporphyrinogen reductase |
| C. | Uroporphyrinogen decarboxylase |
| D. | Coproporphyrinogen oxidase |
| Answer» E. | |
| 24. |
HMP shunt is of great importance in cellular metabolism because it produces - |
| A. | Acetyl CoA |
| B. | NADPH |
| C. | ATP |
| D. | ADP |
| Answer» C. ATP | |
| 25. |
Molecular separation of two proteins with same charge can be done by - |
| A. | Dialysis |
| B. | Ion exchange chromatography |
| C. | Electrophoresis |
| D. | Gel diffusion chromatography |
| Answer» E. | |
| 26. |
Which enzymatic mutation is responsible for immortality of cancer cells - |
| A. | RNA polymerase |
| B. | DNA reserve transciptase |
| C. | DNA polymerase |
| D. | Telomerase |
| Answer» E. | |
| 27. |
Transmination of pyruvate with glutamate produces : |
| A. | Oxaloacetate and alpha-ketoglutarate |
| B. | Alanine and alpha-ketoglutarate |
| C. | Oxaloacetate and aspartate |
| D. | Alanine and aspartate |
| Answer» C. Oxaloacetate and aspartate | |
| 28. |
Non coding RNAs are - |
| A. | siRNA |
| B. | miRNA |
| C. | tRNA |
| D. | All of the above |
| Answer» E. | |
| 29. |
Beta alanine is end product of metabolism of / |
| A. | Uracil |
| B. | Thymine |
| C. | Guanine |
| D. | Adenine |
| Answer» B. Thymine | |
| 30. |
Which of the following is a cardioprotective fatty acid: |
| A. | Oleic acid |
| B. | Omega-3 fatty acid |
| C. | Palmitic acid |
| D. | Stearic acid |
| Answer» C. Palmitic acid | |
| 31. |
Which is not a terminal codon: |
| A. | UGG |
| B. | UAA |
| C. | UGA |
| D. | UAG |
| Answer» B. UAA | |
| 32. |
False regarding gout is: |
| A. | Uric acid levels may not be elevated |
| B. | Has a predilection for the great toe |
| C. | Due to increased metabolism of pyrimidines |
| D. | Due to increased metabolism of purines |
| Answer» D. Due to increased metabolism of purines | |
| 33. |
True statement about transgenic mice - |
| A. | Developed from DNA insertion into fertilized egg |
| B. | Have same genome as parents except one or more gene |
| C. | Homozygous are selected |
| D. | All of the above |
| Answer» E. | |
| 34. |
In DNA transfer the vectors used from smallest to large is - |
| A. | Plasmids, Bacteriophage, Cosmid |
| B. | Cosmid, Plasmids, Bacteriophage |
| C. | Cosmid, Bacteriophage, Plasmids |
| D. | Bacteriophage, Cosmid, Plasmids |
| Answer» B. Cosmid, Plasmids, Bacteriophage | |
| 35. |
Study of structure and products of gene is - |
| A. | Bioinformatics |
| B. | Cytogenetics |
| C. | Genomics |
| D. | Protenomics |
| Answer» D. Protenomics | |
| 36. |
Muscles are not involved in which glycogen storage disease - |
| A. | III |
| B. | IV |
| C. | I |
| D. | II |
| Answer» D. II | |
| 37. |
Okazaki fragments are formed during the synthesis of: |
| A. | m RNA |
| B. | t Rna |
| C. | ds DNA |
| D. | ss DNA |
| Answer» D. ss DNA | |
| 38. |
Methods of introducing gene in target cells are all except: |
| A. | Site directed recombination |
| B. | FISH |
| C. | Electroporation |
| D. | Transfection |
| Answer» C. Electroporation | |
| 39. |
Steroids are indicated in |
| A. | Military tuberculosis |
| B. | Tuberculous meningitis |
| C. | Tuberculosis of spine |
| D. | Endobronchial tuberculosis |
| Answer» C. Tuberculosis of spine | |
| 40. |
The ligand-receptor complex dissociates in the endosome because: |
| A. | The vesicle looses its clathrin cost |
| B. | Of its large size |
| C. | Of the basic pH of the vesicle |
| D. | Of the acidic pH of the vesicle |
| Answer» E. | |
| 41. |
Vitamin required for hydroxyproline to proline conversion - |
| A. | Pyrodoxal PO4 |
| B. | Biotin |
| C. | Vitamin C |
| D. | Vitamin E |
| Answer» D. Vitamin E | |
| 42. |
The most important source of reducing equivalents for fatty acid synthesis in the liver is - |
| A. | Uronic acid pathway |
| B. | HMP pathway |
| C. | Glycolysis |
| D. | TCA cycle |
| Answer» C. Glycolysis | |
| 43. |
IRMA(Immuno-Radiomimetic Assay)uses: |
| A. | Antigen |
| B. | Antibody |
| C. | Ligand |
| D. | Radio labelled test tube |
| Answer» C. Ligand | |
| 44. |
The presence of 2 extra pairs of electrons on the oxygen in water molecule results in - |
| A. | Forms covalent bonds in the ice |
| B. | Makes water a non polar solvent |
| C. | Electro positive charge on water molecule |
| D. | Electro negative charge on water molecule |
| Answer» E. | |
| 45. |
Fumarase is a - |
| A. | Oxidoreductase |
| B. | Lyases |
| C. | Transferase |
| D. | Oxidase |
| Answer» C. Transferase | |
| 46. |
Active moiety of CoA is |
| A. | Thiol of beta-alanine |
| B. | Thiol of pantetheine |
| C. | Acetyl group |
| D. | Pantoic acid |
| Answer» C. Acetyl group | |
| 47. |
If there are 4 nucleotides instead of 3 in codon, how many amino acids may be formed - |
| A. | 21 |
| B. | 16 |
| C. | 64 |
| D. | 256 |
| Answer» E. | |
| 48. |
Enzyme deficiency in Tay-Sachs disease is |
| A. | Hexosaminidase A |
| B. | Hexosaminidase B |
| C. | Sphingomyelinase |
| D. | Beta-Glucosidase |
| Answer» B. Hexosaminidase B | |
| 49. |
Steroids act via nuclear receptors which interact with DNA through - |
| A. | Zinc finger motif |
| B. | Helix turn helix |
| C. | Leucine zipper |
| D. | Histidine |
| Answer» B. Helix turn helix | |
| 50. |
Both vitamin K and C are involved in: |
| A. | Post translational modifications. |
| B. | The synthesis of clotting factors. |
| C. | The mcrosomal hydroxylation reactions. |
| D. | Antioxidant mechanisms. |
| Answer» B. The synthesis of clotting factors. | |