MCQOPTIONS
Saved Bookmarks
MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Mousy odour urine is seen in - |
| A. | Phenylketonuria |
| B. | Maple syrup urine |
| C. | Cystinuria |
| D. | Isovalericaciduria |
| Answer» B. Maple syrup urine | |
| 2. |
Which of the following is precursor of adrenalin and thyroxine synthesis - |
| A. | Phenyl alanine |
| B. | Tyrosine |
| C. | Tryptophan |
| D. | None of the above |
| Answer» C. Tryptophan | |
| 3. |
If starvation exceeds 7 days,the major nutritional supply of the brain comes from |
| A. | Fatty acids |
| B. | Ketone bodies |
| C. | Protein breakdown |
| D. | Carbohydrate breakdown |
| Answer» C. Protein breakdown | |
| 4. |
Histone acetylation cause ? |
| A. | Increased Euchromatin formation |
| B. | Increased Heterochromatin formation |
| C. | DNA replication |
| D. | Methylation of cystine |
| Answer» B. Increased Heterochromatin formation | |
| 5. |
Neoglucogenesis precursors are all except- |
| A. | Ornithine |
| B. | Glycerol |
| C. | Lactate |
| D. | Propionate |
| Answer» B. Glycerol | |
| 6. |
A segment of a eukaryotic gene that is not represented in the mature messenger RNA is known as: |
| A. | Plasmid |
| B. | TATA box |
| C. | Intron |
| D. | Exon |
| Answer» D. Exon | |
| 7. |
In chymotrypsine molecule,if serine-195 is substituted for alanine then: |
| A. | Chymotrypsin will blind but will not cleave |
| B. | Chymotrypsin will not blind to substrate but will cleave the substrate |
| C. | Chymotrypsin will blind and cleave both |
| D. | Chymotrypsin will neither blind to substrate nor cleave |
| Answer» B. Chymotrypsin will not blind to substrate but will cleave the substrate | |
| 8. |
In which of the following reactions is Magnesium required: |
| A. | Dismutase |
| B. | ATPase |
| C. | Aldolase |
| D. | Phosphatase |
| Answer» E. | |
| 9. |
Mitochondrial DNA is - |
| A. | Maternally inherited |
| B. | Paternally inherited |
| C. | Mitochondrial myopathy |
| D. | Mendelian inheritance |
| Answer» B. Paternally inherited | |
| 10. |
The 3 dimensional shape of a protein is maintained mainly by: |
| A. | Strong covalent interactions |
| B. | Interactions with other proteins |
| C. | Multiple weak interactions |
| D. | Interactions with prosthetic groups |
| Answer» D. Interactions with prosthetic groups | |
| 11. |
NADPH is produced by: |
| A. | Glycolysis |
| B. | Citric acid cycle |
| C. | Hexose monophosphate shunt |
| D. | Glycogenesis |
| Answer» D. Glycogenesis | |
| 12. |
Tyrosinemics are more susceptible to develop - |
| A. | Retinoblastoma |
| B. | Hepatic carcinoma |
| C. | Adenocarcinoma colon |
| D. | Melanoma |
| Answer» C. Adenocarcinoma colon | |
| 13. |
Which of the following is an Omega-3 fatty acid ? |
| A. | Linoleic acid |
| B. | Alpha-Linolenic acid |
| C. | Oleic acid |
| D. | Arachidonic acid |
| Answer» C. Oleic acid | |
| 14. |
All of the following metabolic functions occur in the mitochondria,Except |
| A. | Biosynthesis of fatty acids |
| B. | Beta-oxidation of fatty acids |
| C. | Citric acid cycle |
| D. | Protein synthesis |
| Answer» B. Beta-oxidation of fatty acids | |
| 15. |
In which of the following tissues,is glycogen incapable of contributing directly to blood glucose? |
| A. | Muscle |
| B. | Liver |
| C. | None |
| D. | Both |
| Answer» B. Liver | |
| 16. |
Phenyl acetic acid is excreted in the urine in conjugation with: |
| A. | Glycine |
| B. | S-adenosyl methionine |
| C. | Glutamine |
| D. | Glucuronic acid |
| Answer» D. Glucuronic acid | |
| 17. |
One of the following enzyme is not a protein - |
| A. | Eco RI |
| B. | Ribozyme |
| C. | DNAase |
| D. | Abzyme |
| Answer» C. DNAase | |
| 18. |
Which of the following enzymes are activated in dephosphorylated state - |
| A. | Glycogen phosphorylase kinase |
| B. | Citrate lyase |
| C. | HMG CoA reductase |
| D. | Glycogen phosphorylase |
| Answer» D. Glycogen phosphorylase | |
| 19. |
Bile acid synthesized in liver(primary bile acids)- |
| A. | Cholic acid |
| B. | Chenodeoxycholic acid |
| C. | Taurocholic acid |
| D. | All of the above |
| Answer» E. | |
| 20. |
Plasminogen domain resembles - |
| A. | Fibribnogen |
| B. | LDL receptor |
| C. | Apolipoprotein (a) |
| D. | Prothrombin |
| Answer» D. Prothrombin | |
| 21. |
The first gene therapy(somatic enzyme) was successfully done in - |
| A. | Thalassemia |
| B. | Cystic fibrosis |
| C. | SCID |
| D. | Phenylketonuria |
| Answer» D. Phenylketonuria | |
| 22. |
Fluoride ion inhibits - |
| A. | Hexokinase |
| B. | Enolase |
| C. | Phosphofructokinase |
| D. | Aldolase |
| Answer» C. Phosphofructokinase | |
| 23. |
Vitamin K is involved in post translation modification of: |
| A. | Lysine |
| B. | Proline |
| C. | Glutamate |
| D. | Aspartate |
| Answer» D. Aspartate | |
| 24. |
Separation of proteins based on size is done by - |
| A. | Affinity chromatography depending on charge |
| B. | Iron exchange chromatography |
| C. | SDS-Polyacrylamide gel electrophoresis |
| D. | High performance liquid chromatography |
| Answer» D. High performance liquid chromatography | |
| 25. |
All are actions of insulin except: |
| A. | Glycogenesis |
| B. | Lipogenesis |
| C. | Gluconeogenesis |
| D. | Glycolysis |
| Answer» D. Glycolysis | |
| 26. |
The most sensitive index of myocardial infarction is a rise in the plasma level of this enzyme |
| A. | Total creatine kinase |
| B. | Creatine kinase MM |
| C. | Creatine kinase MB |
| D. | Creatine kinase BB |
| Answer» D. Creatine kinase BB | |
| 27. |
Acetyl coA can be directly converted to all except: |
| A. | Cholesterol |
| B. | Ketone bodies |
| C. | Glucose |
| D. | Fatty acids |
| Answer» D. Fatty acids | |
| 28. |
The vitamin used for post-translational modification of glutamic acid to gamma Carboxy-glutamate is |
| A. | Vitamin D |
| B. | Vitamin E |
| C. | Vitamin A |
| D. | Vitamin K |
| Answer» E. | |
| 29. |
Which among the following controls is an allosteric inhibitor of TCA cycle - |
| A. | Keto glutarate dehydrogenase |
| B. | Pyruvate dehydrogenase |
| C. | Malate dehydrogenase |
| D. | Isocitrate dehydrogenase |
| Answer» E. | |
| 30. |
The plasma clearance value of glucose in a diabetes mellitus patient will be - |
| A. | Zero |
| B. | Equal to that of insulin clearance |
| C. | Greater than that of PAH clerance |
| D. | Greater than zero |
| Answer» E. | |
| 31. |
Study of multiplication of proteins in disease process is called; |
| A. | Proteomics |
| B. | Genomics |
| C. | Glycomics |
| D. | Nucleomics |
| Answer» B. Genomics | |
| 32. |
FIGLU excretion in the urine, is an index of the deficiency of |
| A. | Thiamine |
| B. | Niacin |
| C. | Pyridoxine |
| D. | Folate |
| Answer» E. | |
| 33. |
Glycolytic enzymes inhibited by fluoride - |
| A. | Enolase |
| B. | Aldolase |
| C. | Pyruvate kinase |
| D. | Hexokinase |
| Answer» B. Aldolase | |
| 34. |
Zinc acts as co-factor in - |
| A. | Lactate dehydrogenase |
| B. | Alkaline phosphatase |
| C. | Superoxide dismutase |
| D. | All of the above |
| Answer» E. | |
| 35. |
A patient was diagnosed with isolated increase in LDL. His father and brother had the same disease with increased cholesterol. The likely diagnosis is |
| A. | Familial lipoprotein lipase deficiency (type I) |
| B. | LDL receptor mutation |
| C. | Familial type III hyperlipoproteinemia |
| D. | Abetalipoproteinemia |
| Answer» C. Familial type III hyperlipoproteinemia | |
| 36. |
CAP in LAC operon is - |
| A. | Positive regulator |
| B. | Negative regulator |
| C. | Attenuation |
| D. | Constitutive expression |
| Answer» B. Negative regulator | |
| 37. |
DNA fingerprinting was found by - |
| A. | Watson |
| B. | Galton |
| C. | Jeffrey |
| D. | All of the above |
| Answer» D. All of the above | |
| 38. |
Which is true about phage DNA - |
| A. | Restriction enzyme sites |
| B. | Antibiotic susceptibility |
| C. | Carries short segment of DNA |
| D. | Hexagonal DNA |
| Answer» B. Antibiotic susceptibility | |
| 39. |
Triple bonds are found between which base pairs: |
| A. | C-G |
| B. | A-T |
| C. | C-T |
| D. | A-G |
| Answer» B. A-T | |
| 40. |
Enzymes mediating transfer of one molecule to another are: |
| A. | Lysases |
| B. | Peptidases |
| C. | Transferases |
| D. | Oxidases |
| Answer» D. Oxidases | |
| 41. |
Hemoglobin electrophoresis is based on - |
| A. | charge |
| B. | Molecular weight |
| C. | Calorimetric properties |
| D. | Solubility |
| Answer» B. Molecular weight | |
| 42. |
CAP in LAC operon is |
| A. | Attenuation |
| B. | Constitutive expression |
| C. | Positive regulator |
| D. | Negative regulator |
| Answer» D. Negative regulator | |
| 43. |
An enzyme that makes double stranded DNA copy from a single stranded RNA template molecule is known as: |
| A. | RNA polymerase |
| B. | DNA polymerase |
| C. | Phosphokinase |
| D. | Reverse transcriptase |
| Answer» E. | |
| 44. |
False about trans fatty acid - |
| A. | Hydrogenation increases TFA |
| B. | Hydrogenation decreases TFA |
| C. | Increase risk of cardiovascular disease |
| D. | Fried foods have right content of TFA |
| Answer» C. Increase risk of cardiovascular disease | |
| 45. |
RELP, true is - |
| A. | It acts at specific site |
| B. | Endonuclease cuts DNA at nucleotide level |
| C. | Only blunt ends are produced |
| D. | Only cohesive ends are produced |
| Answer» B. Endonuclease cuts DNA at nucleotide level | |
| 46. |
Bile acids consist of all except - |
| A. | Lithocholic acid |
| B. | Taurocholic acid |
| C. | Dexycholic acid |
| D. | Chendexycholic acid |
| Answer» C. Dexycholic acid | |
| 47. |
RNA polymerase does not require: |
| A. | Divalent metal ions(Mn2+,Mg2+) |
| B. | Primer |
| C. | Template (ds DNA) |
| D. | Activated precusors(ATP,GTP,UTP,CTP) |
| Answer» C. Template (ds DNA) | |
| 48. |
PKU is a congenital amino acid metabolic disorder. In one of the following rate variants of PKU Dihydro Biopterin synthesis is affected. The enzyme deficient - |
| A. | Phenylalanine hydroxylase |
| B. | Histidine decarboxylase |
| C. | Tyrosine deficiency |
| D. | Dihydropterin reductase |
| Answer» E. | |
| 49. |
Galactosaemia commonly is due to deficiency of - |
| A. | Glucose -1 phosphatase |
| B. | Glucose -6 phosphatase |
| C. | Galactose -1 phosphate uridyl transferase |
| D. | Galactose -1 phosphatase |
| Answer» D. Galactose -1 phosphatase | |
| 50. |
Hbs has defect in aminoacid position - |
| A. | 6 |
| B. | 4 |
| C. | 12 |
| D. | 11 |
| Answer» B. 4 | |