MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Conversion of DNA to RNA, enzyme required - |
| A. | DNA - Polymerase III |
| B. | RNA - Polymerase |
| C. | DNA - Polymerase I |
| D. | DNA Ligase |
| Answer» C. DNA - Polymerase I | |
| 2. |
Optical transmission through a solution depends on - |
| A. | Path length |
| B. | Concentration |
| C. | Time |
| D. | Scale |
| Answer» C. Time | |
| 3. |
Glucose increase plasma insulin by a process involves - |
| A. | GLUT1 |
| B. | GLUT2 |
| C. | GLUT3 |
| D. | SGLT1 |
| Answer» C. GLUT3 | |
| 4. |
Biological role of metallothioneins is to sequester harmful metal ions.These bind - |
| A. | Pt++, As+++ and PO4- |
| B. | Fe+++, Na+ and K+ |
| C. | Cd++, Cu++ and Zn++ |
| D. | Al+++, Hg++ and NH4- |
| Answer» D. Al+++, Hg++ and NH4- | |
| 5. |
Highest amount of cholesterol is present in - |
| A. | LDL |
| B. | HDL |
| C. | IDL |
| D. | VLDL |
| Answer» B. HDL | |
| 6. |
Decreased glycolytic activity impairs oxygen transport by hemoglobin due to: |
| A. | Decreased production of 2,3-bisphosphoglycerate |
| B. | Reduced energy production |
| C. | Low levels of oxygen |
| D. | Reduced synthesis of hemoglobin |
| Answer» B. Reduced energy production | |
| 7. |
A newborn infant refuses breast milk since the 2nd day of birth, vomits on force-feeding but accepts glucose-water, develops diarrhea on the third day, by 5th day she is jaundiced with liver enlargement and eyes show signs of cataract. Urinary reducing sugar was positive but blood glucose estimated by glucose oxidation method was found low. The most likely cause is deficiency of - |
| A. | Glucose -6 phosphatase |
| B. | Galactokinase |
| C. | Galactose -1 phosphate uridyl transferase |
| D. | Beta galactosidase |
| Answer» D. Beta galactosidase | |
| 8. |
House keeping genes are - |
| A. | Mutant |
| B. | Not regulated |
| C. | Inducible |
| D. | Required only when inducer is present |
| Answer» C. Inducible | |
| 9. |
Polypeptide chain termination is enhanced by - |
| A. | Stop codon |
| B. | Pepitidyl transferase |
| C. | UAA |
| D. | All of the above |
| Answer» E. | |
| 10. |
Mutation that completely disrupt the function of the gene used in which of the following technique - |
| A. | Knock-out |
| B. | Non-sense mutation |
| C. | Knock-in |
| D. | All of the above |
| Answer» B. Non-sense mutation | |
| 11. |
DNA finger printing is done by - |
| A. | Splitting DNA |
| B. | DNA of WBC |
| C. | DNA from nucleated cells |
| D. | All of the above |
| Answer» E. | |
| 12. |
In a patient with starvation for 72 hrs which of the following would be seen: |
| A. | Increased glycogenolysis |
| B. | Increased ketosis due to break down of fats |
| C. | Degradation of proteins |
| D. | Increased gluconeogenesis |
| Answer» C. Degradation of proteins | |
| 13. |
Nitrc oxide is synthesized from ? |
| A. | L-arginine |
| B. | L-citrulline |
| C. | Lysine |
| D. | Tryptophan |
| Answer» B. L-citrulline | |
| 14. |
Phosphorylation of amino acid are - |
| A. | Serine |
| B. | Tryptophan |
| C. | Leucine |
| D. | All of the above |
| Answer» B. Tryptophan | |
| 15. |
Optically inactive Amino Acid is |
| A. | Glycine |
| B. | Proline |
| C. | Leucine |
| D. | Lysine |
| Answer» B. Proline | |
| 16. |
Splenomegaly seen in A/E - |
| A. | Krabbe's disease |
| B. | Neimann pick's disease |
| C. | Sailodosis |
| D. | Gaucher's disease |
| Answer» B. Neimann pick's disease | |
| 17. |
Which of these is a denaturating substance - |
| A. | Guanosine |
| B. | Guanidine |
| C. | Glutamate |
| D. | Glycine |
| Answer» C. Glutamate | |
| 18. |
In a mutation if valine is replaced by which of the following would not result in any change in the function of protein: |
| A. | Proline |
| B. | Leucine |
| C. | Glycine |
| D. | Aspartic acid |
| Answer» E. | |
| 19. |
The urea in the brain is derived from - |
| A. | Lactate |
| B. | Uric acid |
| C. | Glutamine |
| D. | Glutamine acid |
| Answer» D. Glutamine acid | |
| 20. |
Cyanide is toxic because it - |
| A. | Inhibits ATP carrier in mitochondria |
| B. | Inhibits Na-K-ATPase |
| C. | Inhibits cytochrome oxidase |
| D. | Forms cyan meth Hb |
| Answer» D. Forms cyan meth Hb | |
| 21. |
Cytochrome C of the bacteria has 50% identity of amino acid sequence with that of human.Which of the following is the most conserved parameter in these two proteins? |
| A. | Tertiary structure |
| B. | Quarternary structure |
| C. | Loop and turn segments |
| D. | Amino acid sequence |
| Answer» B. Quarternary structure | |
| 22. |
A young man finds that every time he eats dairy products he feels very uncomfortable.His stomach becomes distended he develops gas and diarrhea frequently.These symptoms do not appears when he eats foods other than dairy products.Which of the following is the most likely enzyme in which this young man is deficient? |
| A. | ALFA-glucosidase |
| B. | Sucrase |
| C. | ALFA-amylase |
| D. | BETA-galactosidase |
| Answer» C. ALFA-amylase | |
| 23. |
Glucose-6 phosphatase enzyme is absent in ? |
| A. | Liver |
| B. | Kidney |
| C. | Brain |
| D. | Muscles |
| Answer» E. | |
| 24. |
PUFA is: |
| A. | Palmitic Acid |
| B. | Oleic acid |
| C. | Stearic acid |
| D. | Arachidonic acid |
| Answer» E. | |
| 25. |
Within the RBC,hypoxia stimulates glycolysis by which of the following regulating pathways? |
| A. | Hypoxia stimulates pyruvate dehydrogenase by increased 2,3 DPG |
| B. | Hypoxia inhibits hexokinase |
| C. | Hypoxia stimulates release of all Glycolytic enzymes from Band 3 on RBC membrane |
| D. | Activation of the regulatory enzymes by high pH |
| Answer» D. Activation of the regulatory enzymes by high pH | |
| 26. |
A codon consists of - |
| A. | Three consecutive nucleotide units |
| B. | 2 complementary base pairs |
| C. | Four individual nucleotides |
| D. | An individual ribosome |
| Answer» B. 2 complementary base pairs | |
| 27. |
Cyclic GMP act on |
| A. | Thyroxin |
| B. | Insulin |
| C. | Growth harmone |
| D. | Atrial natriuretic peptide |
| Answer» E. | |
| 28. |
Semiesential amino acids are - |
| A. | Phenylalanine |
| B. | Histidine |
| C. | Glycine |
| D. | All of the above |
| Answer» C. Glycine | |
| 29. |
Glutathione peroxidase contain |
| A. | Mo |
| B. | Se |
| C. | Mn |
| D. | Zn |
| Answer» C. Mn | |
| 30. |
Co-enzyme used in transamination - |
| A. | Biotin |
| B. | Nad |
| C. | Riboflavin |
| D. | Pyridoxal phosphate |
| Answer» E. | |
| 31. |
Which of the following enzyme is common to the synthesis of cholesterol and ketone bodies: |
| A. | HMG-Co-A Lyase |
| B. | HMG-Co-A Reductase |
| C. | Thiokinase |
| D. | HMG-Co-A Synthase |
| Answer» E. | |
| 32. |
Keratin of skin and nail differ because of |
| A. | Disulphide bond |
| B. | Covalent bond |
| C. | Vander Waal bond |
| D. | Hydrogen bond |
| Answer» B. Covalent bond | |
| 33. |
Rough endoplasmic reticulum is site of synthesis for - |
| A. | Protein |
| B. | Cholesterol |
| C. | Carbohydrate |
| D. | Fat |
| Answer» B. Cholesterol | |
| 34. |
All of the following are indications of thiazide diuretics,Except: |
| A. | Nephrolithiasis from idiopathic hypercalciuria |
| B. | Hyperlipidemia |
| C. | Hypertension |
| D. | Heart Failure |
| Answer» C. Hypertension | |
| 35. |
The amino acid which serves as a carrier of ammonia from skeletal muscle to liver is: |
| A. | Arginine |
| B. | Glutamine |
| C. | Alanine |
| D. | Methionine |
| Answer» D. Methionine | |
| 36. |
An elderly male presents with history of dysphagia, regurgitation foul breath and cough.Bilateral Lung crepts are noted on examination.The most likely diagnosis is: |
| A. | Zenker's Diverticulum |
| B. | Shatzki Ring |
| C. | Plummer -Vinson Syndrome |
| D. | Corkscrew Esophagus |
| Answer» B. Shatzki Ring | |
| 37. |
Greyish white membrane in throat may be seen in all of the following infections except: |
| A. | Adenovirus |
| B. | Ludwig's angina |
| C. | Streptococcal tonsilitis |
| D. | Diptheria |
| Answer» C. Streptococcal tonsilitis | |
| 38. |
Cotton's grading is used for ? |
| A. | Subglottic stenosis |
| B. | Laryngeal carcinoma |
| C. | Superior nerve palsy |
| D. | Vocal cord misuse |
| Answer» B. Laryngeal carcinoma | |
| 39. |
Fordyce's (Spots) Granules in Oral Cavity arise from: |
| A. | Sebaceous glands |
| B. | Mucous glands |
| C. | Minor salivary glands |
| D. | Taste buds |
| Answer» B. Mucous glands | |
| 40. |
A 38 year old male presented with a suspected diagnosis of suppurative labyrinthitis. A positive Rinne's test and positive fistula test was recorded on initial examination.The patient refused treatment,and returned to the emergency department after 2 weeks complaining of deafness in the affected ear.On complaining of deafness in the affected ear.On examination,fistula test was observed to be negative.What is the likely expected finding on repeating the Rinne's test. |
| A. | True Negative Rinne's Test |
| B. | False Negative Rinne's Test |
| C. | True Positive Rinne's Test |
| D. | False Positive Rinne's Test |
| Answer» C. True Positive Rinne's Test | |
| 41. |
Fisch classification is used for ? |
| A. | Paravertebral tumours |
| B. | Glomus tumor |
| C. | Synovial sarcoma |
| D. | Retroperitoneal tumours |
| Answer» C. Synovial sarcoma | |
| 42. |
Brown sign is seen in: |
| A. | Glomus tumor |
| B. | Meniere's disease |
| C. | Acoustic neuroma |
| D. | Otosclerosis |
| Answer» B. Meniere's disease | |
| 43. |
On otological examination all of the following will have positive fistula test, except - |
| A. | Hypermobile stapes footplate |
| B. | Following fenestration surgery |
| C. | Dead ear |
| D. | Labyrinthine fistula |
| Answer» D. Labyrinthine fistula | |
| 44. |
Which of the following Lasers is most commonly used in Laryngeal surgery |
| A. | Argon laser |
| B. | KTP laser |
| C. | CO2 laser |
| D. | Nd YAG laser |
| Answer» D. Nd YAG laser | |
| 45. |
Phelps sign is seen in: |
| A. | Glomus jugulare |
| B. | Vestibular shwanoma |
| C. | Menniers disease |
| D. | Neurofibromatosis |
| Answer» B. Vestibular shwanoma | |
| 46. |
Horizontal semicircular canal responds to: |
| A. | Horizontal acceleration |
| B. | Rotating acceleration |
| C. | Gravity |
| D. | Anteroposterior acceleration |
| Answer» C. Gravity | |
| 47. |
Dysphagia for fluids but not to solids is seen in - |
| A. | Stricture |
| B. | Achalasia |
| C. | Carcinoma oesophagus |
| D. | Reflux oesopagitis |
| Answer» C. Carcinoma oesophagus | |
| 48. |
Endolymph in yhe inner ear - |
| A. | Is secrated by Stria vascularis |
| B. | Is a filterate of blood serum |
| C. | Is secrated by hair cells |
| D. | Is secrated by Basilar membrane |
| Answer» B. Is a filterate of blood serum | |
| 49. |
A 30 year old female with history of singing,vocal abuse and gastrooesophageal reflux developed nodules at junction of anterior 1/3rd and middle 3rd of her vocal cords.What is treatment of choice? |
| A. | Microlaryngectomy |
| B. | Direct laryngoscopy and biopsy |
| C. | Speech therapy and Proton Pump Inhibitor (PPI) |
| D. | Microlaryngascopic surgery and CO2 laser |
| Answer» D. Microlaryngascopic surgery and CO2 laser | |
| 50. |
The immediate treatment of CSF rhinorrhea is - |
| A. | Plugging the affected nostril with sterile petrolatum gauze |
| B. | Frequent blowing and cleaning of the nose |
| C. | Immediate craniotomy |
| D. | Wait and watch for 7-10 days, give antibiotics |
| Answer» E. | |