MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The finnish type of congenital nephrotic syndrome occurs due to gene mutations the following protein: |
| A. | Alpha - actinin |
| B. | Podocin |
| C. | CD2 activated protein |
| D. | Nephrin |
| Answer» E. | |
| 2. |
Autosplenectomy is seen in ? |
| A. | Herediatry spherocytosis |
| B. | G6 PD deficiency |
| C. | Sickle cell anemia |
| D. | Thalassemia major |
| Answer» D. Thalassemia major | |
| 3. |
Pale infarcts are seen at all of the following sites except: |
| A. | Kidney |
| B. | Lung |
| C. | Heart |
| D. | Spleen |
| Answer» C. Heart | |
| 4. |
Which amongst the following is a marker of carinoma: |
| A. | Calretinin |
| B. | CD45 |
| C. | Cytokeratin |
| D. | Vimentin |
| Answer» D. Vimentin | |
| 5. |
All of the following are true for complete mole EXCEPT - |
| A. | Diffuse circumferential trophoblastic proliferation |
| B. | Hydropic swelling of villi |
| C. | No fetal parts seen |
| D. | Triploid karyotype |
| Answer» E. | |
| 6. |
Apoptosis is - |
| A. | Cell death induced by regulated intracellular program |
| B. | Cell survival by a regulated ultra cellular program |
| C. | Modification and adaptation by the regulated intracellular program |
| D. | Cell death by an extracellular signal |
| Answer» B. Cell survival by a regulated ultra cellular program | |
| 7. |
A young female patient came for routine examination.On examination a mild systolic click was found.There is no history of RHD.The histopathological examination is most likely to show - |
| A. | Myxomatous degeneration and prolapsed of the mitral valve |
| B. | Fibrinous deposition on the tip of papillary muscle |
| C. | Rupture of chordae tendinae |
| D. | Aschoff nodule on the mitral valve |
| Answer» B. Fibrinous deposition on the tip of papillary muscle | |
| 8. |
Caspases are involved in - |
| A. | Apoptosis |
| B. | Necrosis |
| C. | Inflammation |
| D. | Atherosclerosis |
| Answer» B. Necrosis | |
| 9. |
A female patient presented with a firm mass of 2x2 cms in the upper outer quadrant of the breast.She gives a family history of ovarian carcinoma.The investigation that needs to be done to assess for mutation is: |
| A. | p53 |
| B. | BRCA-2 |
| C. | Her 2/Neu gene |
| D. | C-myc gene |
| Answer» C. Her 2/Neu gene | |
| 10. |
Anti GBM is seen in: |
| A. | Goodpasture |
| B. | RPGN |
| C. | MGN |
| D. | Minimal change disease |
| Answer» B. RPGN | |
| 11. |
True about adult polycystic kidney disease is all,except: |
| A. | Autosomal dominant inheritance |
| B. | Hypertension is rare |
| C. | Can be associated with cysts in liver,lungs and pancreas |
| D. | Pyelonephritis is common |
| Answer» C. Can be associated with cysts in liver,lungs and pancreas | |
| 12. |
Rise in hemoglobin levels after one unit of whole blood transfusion is ? |
| A. | 0.55 |
| B. | 0.01 |
| C. | 0.015 |
| D. | 0.02 |
| Answer» C. 0.015 | |
| 13. |
Pheochromocytoma are neoplasm derived from - |
| A. | Clusters of neuroendocrine cells called paraganglia in adrenal gland |
| B. | Paraganglia in neck |
| C. | An adrenal gland tumor due to nephrogenic rest |
| D. | Primitive totipotential cells |
| Answer» B. Paraganglia in neck | |
| 14. |
The following cereals should be avoided in patients with celiac diseases,except: |
| A. | Wheat |
| B. | Barely |
| C. | Maize |
| D. | Rye |
| Answer» D. Rye | |
| 15. |
Tumorogensis in aging is due to |
| A. | Increased apoptosis |
| B. | Suppression of proto-oncogenes |
| C. | Telomerase reactivation |
| D. | Telomerase inactivation |
| Answer» C. Telomerase reactivation | |
| 16. |
Linitis plastica is found in A/E - |
| A. | Syphillis |
| B. | Carcinoma |
| C. | Sarcoid |
| D. | Leiomyosarcoma |
| Answer» E. | |
| 17. |
CA 125 is used for ? |
| A. | Follow up of ovarian cancer |
| B. | Diagnosis of pancreatic cancer |
| C. | Diagnosis of stomach cancer |
| D. | Diagnosis of ovarian cancer |
| Answer» B. Diagnosis of pancreatic cancer | |
| 18. |
A metastatic carcinoma in the brain of an adult, most often comes from a primary in the - |
| A. | Stomach |
| B. | Ovary |
| C. | Oral cavity |
| D. | Lung |
| Answer» E. | |
| 19. |
All of the following are anticoagulant substances except - |
| A. | Antithrombin III |
| B. | Protein S |
| C. | VWF |
| D. | Nitric oxide |
| Answer» D. Nitric oxide | |
| 20. |
Plasmacytoid Lymphomas may be associated with: |
| A. | IgM |
| B. | IgG |
| C. | IgE |
| D. | IgA |
| Answer» B. IgG | |
| 21. |
All of the following about tumor markers are properly matched except: |
| A. | Prostate cancer -PSA |
| B. | Colon cancer -CEA |
| C. | Ovarian cancer -C.A125 |
| D. | Cholangiocarcinoma -AFP |
| Answer» E. | |
| 22. |
The primary function of Toll like Receptors is ? |
| A. | Vasodilation |
| B. | Activation of Immune System |
| C. | Regarding of Calcium channel |
| D. | Secondary Messenger |
| Answer» C. Regarding of Calcium channel | |
| 23. |
Stem cells are taken from ? |
| A. | Skin |
| B. | Bone marrow |
| C. | Oral mucosa |
| D. | Elementary tract |
| Answer» C. Oral mucosa | |
| 24. |
Which of the following is the most commonly used fixative in diagnostic pathology |
| A. | Mercuric chloride |
| B. | Picric acid |
| C. | Formaldehyde |
| D. | Ethyl alcohol |
| Answer» D. Ethyl alcohol | |
| 25. |
Inflammatory mediator of generalized systemic inflammation: |
| A. | IL-1 |
| B. | IL-2 |
| C. | Interferon a |
| D. | TNF |
| Answer» B. IL-2 | |
| 26. |
A patient has the following findings-splenomegaly,low RBC count,normal WBC,and platelet count and peripheral blood smear shows target cells.Repeated BM aspiration is unsuccessful.The probable diagnosis is: |
| A. | Thalassemia |
| B. | Chronic myeloid leukemia |
| C. | Iron deficiency anaemia |
| D. | Myelofibrosis |
| Answer» E. | |
| 27. |
Gastric carcinoma is associated with all except - |
| A. | Inactivation of p53 |
| B. | Over expression of C -erb |
| C. | Over expression of C -met |
| D. | Activation of RAS |
| Answer» C. Over expression of C -met | |
| 28. |
Which of the following regarding Bombay blood group is false ? |
| A. | Lack of H, A and B antigen on RBCs |
| B. | Lack of H, A and B substance in saliva |
| C. | Lack of antigen of several blood group systems |
| D. | H, A and B antibody will always be present in serum |
| Answer» D. H, A and B antibody will always be present in serum | |
| 29. |
Sap spleen is seen in |
| A. | Gaucher's disease |
| B. | Malaria |
| C. | Amyloidosis |
| D. | Felty's disease |
| Answer» D. Felty's disease | |
| 30. |
Marker of bone formation are all except - |
| A. | Osteocalcin |
| B. | Alkaline phosphatase |
| C. | Procollagen residue |
| D. | Hydroxyproline |
| Answer» E. | |
| 31. |
Commonest histological finding in Benign Hypertension is: |
| A. | Necrotizing arteriolitis |
| B. | Proliferated endarteritis |
| C. | Cystic Medial Necrosis |
| D. | Hyaline arteriosclerosis |
| Answer» E. | |
| 32. |
True about Minimal change disease is: |
| A. | Tram Track appearance |
| B. | Gross haematuria |
| C. | Appears normal under light microscopy but electron microscope shows loss of foot processes |
| D. | Mesangial deposits |
| Answer» D. Mesangial deposits | |
| 33. |
Orbital metastasis is most common in - |
| A. | Hepatoma |
| B. | Melanoma |
| C. | Neuroblastoma |
| D. | Hypernephroma |
| Answer» D. Hypernephroma | |
| 34. |
Extraocular muscles develops from ? |
| A. | Neuroectoderm |
| B. | Mesoderm |
| C. | Ectoderm |
| D. | Endoderm |
| Answer» C. Ectoderm | |
| 35. |
Which component of the eye has maximum refreactive index - |
| A. | Posterior surface of the lens |
| B. | Anterior surface of the lens |
| C. | Cornea |
| D. | Centre of the lens |
| Answer» E. | |
| 36. |
After cataract refers to - |
| A. | Refractive error following cataract surgery |
| B. | Opacity following extra-capsular lens extraction |
| C. | A complication following intra-capsular lens extraction |
| D. | Intraocular implants after cataract extraction |
| Answer» C. A complication following intra-capsular lens extraction | |
| 37. |
Best intraocular lens is placed in - |
| A. | Iris clip |
| B. | Anterior chamber |
| C. | Posterior chamber |
| D. | Any of the above |
| Answer» D. Any of the above | |
| 38. |
Treatment of choice for amblyopia is - |
| A. | Convergent exercise |
| B. | Spectacles |
| C. | Surgery |
| D. | Conventional occlusion |
| Answer» E. | |
| 39. |
The WHO definition of low vision children: |
| A. | Visual acuity 3/60 to 6/18 in better eye with best correction |
| B. | Visual acuity 6/60 to 3/60 in better eye with best correction |
| C. | Visual acuity <3/60 in better eye with best available correction |
| D. | Visual acuity 6/18 to 6/60 in better eye with best correction |
| Answer» E. | |
| 40. |
Angle of strabismus measured by - |
| A. | Forced duction test |
| B. | Prism cover test |
| C. | Lister's perimeter |
| D. | Bruchner's test |
| Answer» C. Lister's perimeter | |
| 41. |
First sign of optic nerve disease is - |
| A. | Papilloedema |
| B. | Colour blindness |
| C. | Afferent pupillary defect |
| D. | Efferent pupillary defect |
| Answer» D. Efferent pupillary defect | |
| 42. |
Which action of extra-ocular muscle is spared in involvement of Occulomotor nerve: |
| A. | Elevation |
| B. | Adduction |
| C. | Abduction |
| D. | Depression |
| Answer» D. Depression | |
| 43. |
Blow out fracture of the orbit,most commonly leads to fracture of - |
| A. | Lateral wall of orbit |
| B. | Roof of orbit |
| C. | Posteromedial floor of orbit |
| D. | Medial wall of orbit |
| Answer» D. Medial wall of orbit | |
| 44. |
Exudative retinal detachment occurs in |
| A. | Myopia |
| B. | Diabetes mellitus |
| C. | Pregnancy induced hypertension |
| D. | Trauma |
| Answer» D. Trauma | |
| 45. |
An 18 year old boy comes to the eye casuality with history of injury with a tennis ball.On examination there is no perforation but there is hyphaema.The most likely source of the blood is |
| A. | Circulus iridis major. |
| B. | Iris vessels. |
| C. | Short posterior ciliary vessels. |
| D. | Circulus iridis minor. |
| Answer» B. Iris vessels. | |
| 46. |
A patient with clinically signifacant diabetic macular edema with non progressive diabetic retinopathy was treated with Macular grid photocoagulation.The patient still has vitreo macular traction.What is the preferred treatment? |
| A. | Pars plana vitrectomy |
| B. | Intravitreal bevacizumab |
| C. | Augmented macula photocoagulation |
| D. | Repeat macular grid photocoagulation |
| Answer» B. Intravitreal bevacizumab | |
| 47. |
In a patient with AIDS chorioretinitis is typically caused by |
| A. | Cytomegalovirus |
| B. | Toxoplasma gondii |
| C. | Cryptococcus neoformans |
| D. | Histoplasma capsulatum |
| Answer» B. Toxoplasma gondii | |
| 48. |
Extra retinal fibrovascular proliferation at ridge between normal and avascular retina is which grade of ROP ? |
| A. | ROP 1 |
| B. | ROP 2 |
| C. | ROP 3 |
| D. | ROP 4 |
| Answer» D. ROP 4 | |
| 49. |
Fluorescein angiography is used to identify lesions in all except: |
| A. | Retina |
| B. | Lens |
| C. | Optic nerve head |
| D. | Iris |
| Answer» C. Optic nerve head | |
| 50. |
Leucokoria can be seen in all except: |
| A. | Persistant hyperplastic primary vitreous |
| B. | Congenital glaucoma |
| C. | Fungal endopthalmitis |
| D. | Retinoblastoma |
| Answer» C. Fungal endopthalmitis | |