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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
New drug study and development can be done by: |
| A. | Pharmacogenetics |
| B. | Molecular modelling |
| C. | Pharmaco library |
| D. | Neo pharmacy |
| Answer» B. Molecular modelling | |
| 2. |
Iron Deficiency Anemia which statement is not true - |
| A. | Latent stage is most common in India |
| B. | Can Be Detected Early By Serum Ferritin Levels |
| C. | Decreased Transferritin Saturation less Than 16% |
| D. | Asymptomatic Clinically But Lab Findings Increased |
| Answer» E. | |
| 3. |
An undifferentiated malignant tumour on immunohistochemical stain shows cytoplasmic positivity of most of the tumour cells for cytokeratin.The most probable diagnosis of the tumour is - |
| A. | Lymphoma |
| B. | Sarcoma |
| C. | Malignant melanoma |
| D. | Carcinoma |
| Answer» E. | |
| 4. |
McCallum's patch is diagnostic of |
| A. | Infective endocarditis |
| B. | Rheumatic endocarditis |
| C. | Myocardial infarction |
| D. | Tetralogy of Fallot (ToF) |
| Answer» C. Myocardial infarction | |
| 5. |
Liquefactive necrosis is typically seen in - |
| A. | Ischemic necrosis of the heart |
| B. | Ischemic necrosis of the brain |
| C. | Ischemic necrosis of the intestine |
| D. | Tuberculosis |
| Answer» C. Ischemic necrosis of the intestine | |
| 6. |
The following host tissue responses can be seen in acute infection,except: |
| A. | Margination |
| B. | Granuloma formation |
| C. | Exudation |
| D. | Vasodilation |
| Answer» C. Exudation | |
| 7. |
Which is not a 2nd generation antihistamine? |
| A. | Cyclizine |
| B. | Cetrizine |
| C. | Fexofenadine |
| D. | Loratidine |
| Answer» B. Cetrizine | |
| 8. |
All are endogenous catecholamines except - |
| A. | Dopamine |
| B. | Dobutamine |
| C. | Epinephrine |
| D. | Norepinephrine |
| Answer» C. Epinephrine | |
| 9. |
Tamm Horsfall protein is produced by - |
| A. | Ureter |
| B. | Collecting duct |
| C. | Loop of Henle |
| D. | Distal tubule |
| Answer» D. Distal tubule | |
| 10. |
Propanalol is indicated in all of the following conditions except: |
| A. | Varientangina |
| B. | Thyrotoxicosis |
| C. | Hypertension |
| D. | Migraine |
| Answer» B. Thyrotoxicosis | |
| 11. |
One of the potent microsomal enzymes inducer drug is |
| A. | Captopril |
| B. | Erythromycin |
| C. | Rifampicin |
| D. | Cimetidine |
| Answer» D. Cimetidine | |
| 12. |
Advantages of 3rd generation cephalosporins over 1st and 2nd generation cephalosporins is that they are |
| A. | Beta-lactamase sensitive |
| B. | Not orally administered |
| C. | Effective against Gram +ve bacteria |
| D. | Effective against Gram -ve bacteria |
| Answer» E. | |
| 13. |
Partial agonist of opioid receptors: |
| A. | Buprenorphine |
| B. | Morphine |
| C. | Methadone |
| D. | Naloxone |
| Answer» B. Morphine | |
| 14. |
In Marfan's syndrome,Aortic aneurysm occurs most commonly in: |
| A. | Ascending aorta |
| B. | Descending aorta |
| C. | Abdominal aorta |
| D. | Arch of aorta |
| Answer» B. Descending aorta | |
| 15. |
All the following characteristics are true of Liposarcoma except that it - |
| A. | Is commonly found in the retro-peritoneum |
| B. | Frequently gives rise to embolization in lymphatics |
| C. | Is the most common soft tissue sarcoma |
| D. | Arises very rarely in subcutaneous tissue |
| Answer» C. Is the most common soft tissue sarcoma | |
| 16. |
Bacitracin acts on: |
| A. | Nucleic Acid |
| B. | Ribosome |
| C. | Cell Wall |
| D. | Cell Membrane |
| Answer» D. Cell Membrane | |
| 17. |
Adverse effects of losartan are all except - |
| A. | Angioedema |
| B. | Cough |
| C. | Hyperkalemia |
| D. | Headache |
| Answer» C. Hyperkalemia | |
| 18. |
Misoprostol is a: |
| A. | Prostaglandin antagonist |
| B. | Antiprogestin |
| C. | Prostaglandin E1 analogue |
| D. | Prostaglandin E2 analogue |
| Answer» D. Prostaglandin E2 analogue | |
| 19. |
Peripheral neuropathy may occur with the use of all the following except: |
| A. | Vincristine |
| B. | Cisplatine |
| C. | L-Asparaginase |
| D. | Procarbazine |
| Answer» D. Procarbazine | |
| 20. |
When a drug is evaluated for its usefulness in controlled conditions, it is termed as a trial signifying: |
| A. | Efficiency |
| B. | Effect modification |
| C. | Efficacy |
| D. | Effectiveness |
| Answer» D. Effectiveness | |
| 21. |
Not used in erectile dysfunction ? |
| A. | Vardalafil |
| B. | PGE-2 |
| C. | Alprostadil |
| D. | Phenylephrine |
| Answer» E. | |
| 22. |
The most common side effect of chronic use of phenothiazines is |
| A. | Akathisia |
| B. | Tardive akinesia |
| C. | Tardive dyskinesia |
| D. | Muscular dystonia |
| Answer» D. Muscular dystonia | |
| 23. |
A patient with sinusitis,on terfenadine for a long time,develops cough and URTI.His physician prescribes him erythromycin.The expected side effect is: |
| A. | Cardiac arrhythmia |
| B. | Allergic reaction |
| C. | Low terfenadine level |
| D. | Rashes all over body |
| Answer» B. Allergic reaction | |
| 24. |
Which of the following statements is not true about Tacrolimus? |
| A. | Glucose intolerance is a well Recognized side effect |
| B. | It can be safely administered with any Nephrotoxic drug |
| C. | It is macrolide Antibiotic |
| D. | It is indicated for the prophylaxis of organ transplant rejection |
| Answer» C. It is macrolide Antibiotic | |
| 25. |
Which of the following is TRUE for morphine: |
| A. | Tolerate to all its actions except sedation and euphoria |
| B. | Tolerate to all side effects except conpitation and miosis |
| C. | It is a peripherally acting analgesic |
| D. | It has no abuse potential |
| Answer» C. It is a peripherally acting analgesic | |
| 26. |
All are true regarding antiarrhythmic,except: |
| A. | Verapamil belongs to second group drugs |
| B. | It is drug of choice for PSVT |
| C. | It is contraindicated in complete heart block |
| D. | It depresses heart rate |
| Answer» B. It is drug of choice for PSVT | |
| 27. |
Pneumopathy is a side effect of all, except - |
| A. | Alpha methyldopa |
| B. | Busulphan |
| C. | Melphalan |
| D. | Nitrofurantoin |
| Answer» B. Busulphan | |
| 28. |
Amphoterecin B toxicity can be lowered by |
| A. | Decreasing the dose |
| B. | Giving it with Glucose |
| C. | Combining with flucytosine |
| D. | Using Liposomal delivery systems |
| Answer» E. | |
| 29. |
Which non depolarizing agent is a ganglion blocker - |
| A. | Atracurium |
| B. | Pancuronium |
| C. | D-TC |
| D. | Gallamine |
| Answer» D. Gallamine | |
| 30. |
RPGN occurs in A/E - |
| A. | SLE |
| B. | Post streptococcal glomerulonephritis |
| C. | Diabetic nephropathy |
| D. | Good pastures syndromes |
| Answer» D. Good pastures syndromes | |
| 31. |
Macrophages are found in - |
| A. | Phase of scar formation |
| B. | Phase of repair |
| C. | Late phase of inflammation |
| D. | Early phase of inflammation |
| Answer» D. Early phase of inflammation | |
| 32. |
A mylocardial infarct showing early granulation tissue has most likely occured |
| A. | Within 24 hrs |
| B. | Less than 1 hours |
| C. | Within 1 month |
| D. | Within 1 week |
| Answer» E. | |
| 33. |
Which component of HBV causes glomerul-onephritis: |
| A. | HbeAg |
| B. | HBcAg |
| C. | HBsAg |
| D. | Anti HBsAg antibody |
| Answer» D. Anti HBsAg antibody | |
| 34. |
Which of these is true regarding CML: |
| A. | Size of splenomegaly indicates prognosis |
| B. | Phagocytic activity of WBC is reduced |
| C. | Sudan black stain is specific for myeloblast |
| D. | Myeloblast,granuloblast and lymphoblast are PH chromosome +ve. |
| Answer» B. Phagocytic activity of WBC is reduced | |
| 35. |
Retrovirus is used for gene therapy because- |
| A. | They have sequences common to human genome |
| B. | They integrate rapidly into human genome |
| C. | Economically viable |
| D. | Easy to perform in labs |
| Answer» C. Economically viable | |
| 36. |
Fasciculations are caused by - |
| A. | Vecuronium |
| B. | Suxamethonium |
| C. | Atracurium |
| D. | Pancuronium |
| Answer» C. Atracurium | |
| 37. |
Most common benign tumour of liver is - |
| A. | Papilloma |
| B. | Hepatic adenoma |
| C. | Amoeboma |
| D. | Hemangioma |
| Answer» E. | |
| 38. |
Drug used in treatment of carcinoma thyroid is - |
| A. | Doxorubicin |
| B. | 5-Flurouracil |
| C. | Methotrexate |
| D. | Vinblastine |
| Answer» B. 5-Flurouracil | |
| 39. |
All are inotropic agents, except - |
| A. | Isoprenaline |
| B. | Amiodarone |
| C. | Dopamine |
| D. | Amrinone |
| Answer» C. Dopamine | |
| 40. |
BAL is used for chelation of all except |
| A. | Lead |
| B. | Mercury |
| C. | Cadmium |
| D. | Arsenic |
| Answer» D. Arsenic | |
| 41. |
Deficiency of this hemophilic factor during early pregnancy will result in neural tube defect - |
| A. | Folic acid |
| B. | Iron |
| C. | Cynocobalamine |
| D. | Antioxidants |
| Answer» B. Iron | |
| 42. |
Imatinib used in CML acts by - |
| A. | Blocking the action of P-glycoprotein |
| B. | Inhibiting Bcr/abl translocation via tyrosine kinase |
| C. | C-kit kinase inhibition |
| D. | Competitive inhibition of ATP binding site of Abl kinase |
| Answer» E. | |
| 43. |
Which of the following statements is true about ketorolac ? |
| A. | It has potent anti inflammatory activity |
| B. | It's analgesic efficacy is equal to morphine in post operative pain |
| C. | Is used as preanesthetic medication |
| D. | It interacts with opioid receptors |
| Answer» C. Is used as preanesthetic medication | |
| 44. |
Regarding adverse reaction,all are correct,EXCEPT: |
| A. | Methysergide - Retroperitoneal fibrosis |
| B. | Rifampicin - Optic neuritis |
| C. | Saralasin - AT2 receptor antagonist |
| D. | Ethambutol - Retrobulbar neuritis |
| Answer» C. Saralasin - AT2 receptor antagonist | |
| 45. |
Which of the following cephalosporins does not need dose modifications even in presence of raised levels of GFR |
| A. | Cefoperazone |
| B. | Cefipime |
| C. | Cefuroxime |
| D. | Cefotaxim |
| Answer» B. Cefipime | |
| 46. |
Haemorrhage secondary to human administration can be corrected by administration of: |
| A. | Whole blood |
| B. | Vitamin K |
| C. | Ascorbic acid |
| D. | Protamine |
| Answer» E. | |
| 47. |
In drug metabolism, hepatic cytochrome P450 system is responsible for - |
| A. | Phase I reactions (hydrolysis, oxidation, reduction, etc.) only |
| B. | Phase II reactions (conjugation, synthesis, etc.) only |
| C. | Both phase I and phase II reactions |
| D. | Converting hydrophilic metabolites to lipophilic metabolites |
| Answer» B. Phase II reactions (conjugation, synthesis, etc.) only | |
| 48. |
Which of the following drug is used in sickle cell anemia- |
| A. | Paclitaxel |
| B. | Bleomycin |
| C. | Hydroxyurea |
| D. | Carmustine |
| Answer» D. Carmustine | |
| 49. |
Side effects of a drug arise due to the interactions of the drug to molecules other than the target.These effects of a drug can be minimized by its high - |
| A. | Specificity |
| B. | Affinity |
| C. | Solubility |
| D. | Hydrophobicity |
| Answer» B. Affinity | |
| 50. |
Cerebellar toxicity is seen with |
| A. | Cytarabine |
| B. | Cisplatin |
| C. | Actinomycin D |
| D. | Bleomycine |
| Answer» B. Cisplatin | |