MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
With chronic use in seizure state, the adverse effects of this drug include coarsening of facial features, hirsutism, gingival hyperplasia and osteomalacia - |
| A. | Carbamazepine |
| B. | Ethosuccimide |
| C. | Gabapentin |
| D. | Phenytoin |
| Answer» E. | |
| 2. |
Food does not interfere in absorption of |
| A. | Cimetidine |
| B. | Ranitidine |
| C. | Famotidine |
| D. | None of the above |
| Answer» B. Ranitidine | |
| 3. |
Which of the following is associated with adult polycystic kidney disease? |
| A. | Berry aneurysms in Circle of Willis |
| B. | Saccular aneurysms of aorta |
| C. | Fusiform aneurysms of aorta |
| D. | Leutic aneurysms |
| Answer» B. Saccular aneurysms of aorta | |
| 4. |
A testicular tumor marker is |
| A. | Alpha-Fetoprotein |
| B. | Ectopic hormones |
| C. | CEA |
| D. | Testosterone |
| Answer» B. Ectopic hormones | |
| 5. |
Caspases are involved in: |
| A. | Necrosis |
| B. | Cell division |
| C. | Inflammation |
| D. | Apoptosis |
| Answer» E. | |
| 6. |
Amiodarone causes all,EXCEPT: |
| A. | Hyperthyroidism |
| B. | Pulmonary fibrosis |
| C. | Hyperuricemia |
| D. | Hypothyroidism |
| Answer» D. Hypothyroidism | |
| 7. |
Extrapyramidal syndrome is least in: |
| A. | Chlorpromazine |
| B. | Haloperidol |
| C. | Olanzepine |
| D. | Fluphenazine |
| Answer» D. Fluphenazine | |
| 8. |
All are TRUE, EXCEPT |
| A. | Bronchiolitis in infant is caused by respiratory syncytial virus |
| B. | ECHO virus cause haemorrhagic conjunctivitis |
| C. | CMV retinitis and esophagitis is seen in immuno-compromised patients |
| D. | Marburg virus causes-haemorrhagic fever |
| Answer» C. CMV retinitis and esophagitis is seen in immuno-compromised patients | |
| 9. |
Chronic venous congestion of lung is characterized by following features EXCEPT |
| A. | Necrosis of alveolar septae |
| B. | Congested capillaries |
| C. | Heart failure cells |
| D. | Congested alveoli |
| Answer» B. Congested capillaries | |
| 10. |
In low doses aspirin acts on: |
| A. | PGI2 |
| B. | Lipoxygenase |
| C. | Cyclo-oxygenase |
| D. | Thromboxane A2 |
| Answer» D. Thromboxane A2 | |
| 11. |
If a diabetic patient being treated with an oral hypoglycemic agent,develops dilutional hyponatremia-which one of the following could be responsible for this effect: |
| A. | Chlorpropamide |
| B. | Tolazamide |
| C. | Glyburide |
| D. | Glimepiride |
| Answer» B. Tolazamide | |
| 12. |
Thiazides false is - |
| A. | Increases uric acid concentration in serum |
| B. | Increases calcium excretion in urine |
| C. | Used in CCF |
| D. | Causes hyperglycemia |
| Answer» C. Used in CCF | |
| 13. |
Drug used for common cold that can cause stroke is ? |
| A. | Phenylpropanolamine |
| B. | Oxametazoline |
| C. | Phenylephrine |
| D. | All of the avove |
| Answer» B. Oxametazoline | |
| 14. |
Which drug is not Cardiotoxic |
| A. | Cyclophosphamide |
| B. | 5-FU |
| C. | Adriamycin |
| D. | Cisplatin |
| Answer» E. | |
| 15. |
Drug absolutely contraindicated in pregnancy - |
| A. | Nifedipine |
| B. | Enalapril |
| C. | Diazoxide |
| D. | Atenolol |
| Answer» C. Diazoxide | |
| 16. |
If Theophylline is used with Ciprofloxacin |
| A. | Toxicity of Theophylline increases |
| B. | Efficacy decreases |
| C. | Activity of Ciprofloxacin increases |
| D. | It decreases absorption of Theophylline |
| Answer» B. Efficacy decreases | |
| 17. |
Which of the following statements about anti-epileptics is false - |
| A. | Phenytoin and carbamazepine act by prolonging Na+ channel activation |
| B. | Carbamazepine is also used in trigeminal neuralgias |
| C. | Diazepam is an anti-epileptics |
| D. | Lamotrrigine acts by GABA mediated Cl- channel opening |
| Answer» E. | |
| 18. |
Most potent antiemetic used in pre medications is - |
| A. | Atropine |
| B. | Hyoscine |
| C. | Glycopyrrolate |
| D. | Chlorpromazine |
| Answer» C. Glycopyrrolate | |
| 19. |
Drugs of choice for the treatment of neurocysticercosis are |
| A. | Hydroquinone and metronidazole |
| B. | Metronidazole and pyrantel palmoate |
| C. | Albendazole and praziquantel |
| D. | Praziquantel and chloroquine |
| Answer» D. Praziquantel and chloroquine | |
| 20. |
True about imipenem is ? |
| A. | It is a narrow spectrum antibiotic |
| B. | It is easily broken by beta lactam |
| C. | It can be used with cilastatin |
| D. | It is used with sulbactam |
| Answer» D. It is used with sulbactam | |
| 21. |
The epitheloid cell and multinucleated gaint cells of Granulomatous inflammation are derived from: |
| A. | CD4-T lymphocytes |
| B. | Monocytes - Macrophages |
| C. | Basophils |
| D. | Eosinophils |
| Answer» C. Basophils | |
| 22. |
A parent is homozygous and a parent heterozygous for an autosomal recessive gene. What will be outcome ? |
| A. | 75% children affected |
| B. | No children affected, but all are carriers |
| C. | 50% children affected, rest are carriers |
| D. | 25% children affected, rest are carriers |
| Answer» D. 25% children affected, rest are carriers | |
| 23. |
Most common fixative used in electron microscopy |
| A. | Picric acid |
| B. | Absolute Alcohol |
| C. | Glutaraldehyde |
| D. | Formalin |
| Answer» D. Formalin | |
| 24. |
Osteoclastic giant cells are seen in all except: |
| A. | Osteoclastoma |
| B. | Osteoblastoma |
| C. | Aneurysmal bone cyst |
| D. | Chondroblastoma |
| Answer» C. Aneurysmal bone cyst | |
| 25. |
The extent to which ionization of a drug takes place is dependent upon pKa of the drug and the pH of the solution in which the drug is dissolved. Which of the following statements is not correct: |
| A. | Small changes of pH near the pKa of a weak acidic drug will not affect its degree of ionization. |
| B. | pKa of a drug is the pH at which the drug is 50% ionized |
| C. | Phenobarbitone with a pKa of 7.2 is largely ionized at acid pH and will be about 40% non-ionized in plasma. |
| D. | Knowledge of pKa of a drug is useful in predicting its behaviour in various body fluids. |
| Answer» B. pKa of a drug is the pH at which the drug is 50% ionized | |
| 26. |
Which of the following antiepileptic agents acts on the GABAergic system to decrease the uptake of GABA into neurons and glial cells - |
| A. | Vigabatrin |
| B. | Progabide |
| C. | Gabapentin |
| D. | Tiagabine |
| Answer» E. | |
| 27. |
The blood culture from a patient of febrile neutropenia has grown Pseudomonas aeruginosa, It was found to be a producer of extended spectrum beta lactamase enzyme.The best choice of antimicrobial therapy should be - |
| A. | Ceftazidine + Amikacin |
| B. | Aztreonam + Amikacin |
| C. | Cefpirome + Amikacin |
| D. | Imipenem + Amikacin |
| Answer» E. | |
| 28. |
Which of the following is False about Pentazocine |
| A. | Decreased vomiting and constipation as compared to morphine |
| B. | Risk of addiction is less than that with morphine |
| C. | Risk of addiction is more than that with morphine |
| D. | It is agonist-antagonist |
| Answer» D. It is agonist-antagonist | |
| 29. |
The antiretroviral drug which is also effective in chronic active hepatitis-B infection is - |
| A. | Zidovudine |
| B. | Nelfinavir |
| C. | Efavirenz |
| D. | Lamivudine |
| Answer» E. | |
| 30. |
Which of the following drugs is known to cause vaginal adenocarcinoma in female offspring when given to a pregnant woman |
| A. | Chlorpropamide |
| B. | Progesterone |
| C. | Diethylstilbestrol |
| D. | Chloramphenicol |
| Answer» D. Chloramphenicol | |
| 31. |
All are true about Cotrimoxazole, except - |
| A. | Resistance is delayed due to drug in combination |
| B. | Trimethoprim : Sulphamethoxazole = 1:5 |
| C. | Similar pharmacokinetics for both components |
| D. | Trimethoprim increases absorption of Sulphamethoxazole |
| Answer» E. | |
| 32. |
Bremelanotide used for - |
| A. | Erectile dysfunction |
| B. | LUTS |
| C. | Prostate cancer |
| D. | Metastatic renal cancer |
| Answer» B. LUTS | |
| 33. |
Commonest site of lytic lesion in multiple myeloma is: |
| A. | Clavicle |
| B. | Pelvis |
| C. | Vertebral column |
| D. | Femur |
| Answer» D. Femur | |
| 34. |
Syncytial osteoclastic giant cells are seen in all except: |
| A. | Osteosarcoma |
| B. | Ewing's sarcoma |
| C. | Chondroblastoma |
| D. | Aneurysmal bone cyst |
| Answer» B. Ewing's sarcoma | |
| 35. |
True about cell ageing- |
| A. | Free radicals injury |
| B. | Mitochondria are increased |
| C. | Lipofuscin accumulation in the cell |
| D. | Size of cell increased |
| Answer» D. Size of cell increased | |
| 36. |
Laminin is found in the |
| A. | Outer nuclear membrane |
| B. | Inner nuclear membrane |
| C. | Basement membrane |
| D. | Endothelium |
| Answer» D. Endothelium | |
| 37. |
Characteristic of protective epithelium is - |
| A. | Regeneration of membrane |
| B. | Microvilli |
| C. | Thinness |
| D. | Pinocytic vesicle |
| Answer» B. Microvilli | |
| 38. |
Gene instability associated with malignancy in- |
| A. | Ataxia telangiectasia |
| B. | Klippel field syndrome |
| C. | Sickle cell disease |
| D. | Marfan's syndrome |
| Answer» B. Klippel field syndrome | |
| 39. |
A patient develops hypoglycemia. He was on insulin and acarbose. For treatment of above what is to be given - |
| A. | Sucrose |
| B. | Starch |
| C. | Glucose |
| D. | Maltose |
| Answer» D. Maltose | |
| 40. |
Drug which causes hypothyroidism is - |
| A. | Carbamezapine |
| B. | Lithium |
| C. | Sulphur |
| D. | Methotrexate |
| Answer» C. Sulphur | |
| 41. |
Severe alcoholic for 15 years, not taking for 2 days developed tremors, on first day and Tonic clonic seizures on second day. Which drug should be given to treat seizures ? |
| A. | Valproate |
| B. | Phnytoin |
| C. | Diazepam |
| D. | Carbamazepine |
| Answer» D. Carbamazepine | |
| 42. |
Which of the following is not a therapeutic use of prostaglandins ? |
| A. | Therapeutic abortion |
| B. | Gastric cytoprotection |
| C. | Crohn's disease |
| D. | Impotent patients who do not have disorders of the vascular system |
| Answer» D. Impotent patients who do not have disorders of the vascular system | |
| 43. |
Pupil fails to dilate by giving cocaine in: |
| A. | Central sympathetic paralysis |
| B. | Central parasympathetic paralysis |
| C. | Peripheral parasympathetic paralysis |
| D. | Peripheral sympathetic paralysis |
| Answer» E. | |
| 44. |
All of the following drugs cause hyperprolactenemia except - |
| A. | Methyldopa |
| B. | Chlorpromazine |
| C. | Bromocriptine |
| D. | Metoclopramide |
| Answer» D. Metoclopramide | |
| 45. |
In treatment of cardiac failure,dobutamine acts by all of the following mechanisms except: |
| A. | Beta adrenergic receptors agonism |
| B. | Alpha receptors agonism |
| C. | Increasing force of contraction |
| D. | Dopamine receptor agonism |
| Answer» E. | |
| 46. |
Which of the following has X-linked recessive inheritance ? |
| A. | G6PD deficiency |
| B. | Sickle cell anaemia |
| C. | Thalassemia |
| D. | Hereditary spherocytosis |
| Answer» B. Sickle cell anaemia | |
| 47. |
All are true regarding prazosin, except - |
| A. | First dose effect |
| B. | Impaired glucose tolerance |
| C. | Selective alpha-1 blocker |
| D. | Is an antihypertensive drug |
| Answer» C. Selective alpha-1 blocker | |
| 48. |
Most common side effect of 5-Fluoro-uracil is: |
| A. | Cardiotoxicity |
| B. | Neurotoxicity |
| C. | G.I.toxicity |
| D. | Bone marrow depression |
| Answer» D. Bone marrow depression | |
| 49. |
The treatment of contacts of meningococcal meningitis is by: |
| A. | Penicillin |
| B. | Cephalosporins |
| C. | Rifampicin |
| D. | Erythromycin |
| Answer» D. Erythromycin | |
| 50. |
Pancreatitis is a known side effect with administration of |
| A. | Cyclophosphamide |
| B. | Vincristine |
| C. | L-Asparaginase |
| D. | Corticosteroid |
| Answer» D. Corticosteroid | |