MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Ammonia is detoxified in brain to: |
| A. | Glutamine |
| B. | Urea |
| C. | Uric acid |
| D. | GABA |
| Answer» B. Urea | |
| 2. |
Nitric Oxide Synthase: |
| A. | Accepts electrons from NADH |
| B. | Requires NADPH,FAD,FMN and Heme iron |
| C. | Is inhibited by Ca++ |
| D. | Catalyzes a dioxygenase reaction |
| Answer» C. Is inhibited by Ca++ | |
| 3. |
Thiamine acts as a cofactor in: |
| A. | Oxidation in respiratory chain |
| B. | Conversion of pyridoxal to pyridoxal phosphate |
| C. | Conversion of pyruvate to acetyl-CoA |
| D. | Transamination reactions |
| Answer» D. Transamination reactions | |
| 4. |
All are true about glutathione except - |
| A. | It converts hemoglobin to methemoglobin |
| B. | It is tripeptide |
| C. | It scavenges free radicals and superoxide ions |
| D. | It conjugates xenobiotics |
| Answer» B. It is tripeptide | |
| 5. |
Excessive ultraviolet(uv) radiation is harmful to life. The damage caused to the biological system by ultraviolet radiation I by - |
| A. | Formation of thymidine dimmers |
| B. | Inhibition of DNA synthesis |
| C. | DNA fragmentation |
| D. | Ionization |
| Answer» B. Inhibition of DNA synthesis | |
| 6. |
Tyrosinase is - |
| A. | Lyase |
| B. | Isomerase |
| C. | Oxidase |
| D. | Transferase |
| Answer» D. Transferase | |
| 7. |
Which of the following statements about faciliated diffusion is true |
| A. | It requires a carrier protein |
| B. | It is a form of active transport |
| C. | Requires creating phosphate |
| D. | Rate of transport is proportionate to the concentration gradient |
| Answer» B. It is a form of active transport | |
| 8. |
Transport of ADP in and ATP out of mitochondria is inhibited by- |
| A. | rotenone |
| B. | cyanide |
| C. | atractyloside |
| D. | oligomycin |
| Answer» D. oligomycin | |
| 9. |
In a solution the concentration of hydrogen ion(H+) is 1 x 10-6 moles/litre.The pH of the solution will be - |
| A. | Six |
| B. | Three |
| C. | Twelve |
| D. | Nine |
| Answer» B. Three | |
| 10. |
Basement membrane is abundant in: |
| A. | Type I collagen |
| B. | Type II collagen |
| C. | Type III collagen |
| D. | Type IV collagen |
| Answer» E. | |
| 11. |
A protein with molecular weight of 100 kD is subjected to SDS PAGE electrophoresis.The SDS PAGE electrophoresis pattern show two widely separated bands of 20kD and 30kD after addition of Mercaptoethanol.The true statement regarding this will be. |
| A. | The protein is a dimer of two 20kD and 30kD proteins |
| B. | The protein is a tetramer of two 20kD and 30kD proteins |
| C. | The protein has undergone complete lysis |
| D. | The protein is a monomer of 20kD and 30kD protein |
| Answer» D. The protein is a monomer of 20kD and 30kD protein | |
| 12. |
The pain products of HMP shunt are all except - |
| A. | 1-Glyceraldehyde-3-PO4 |
| B. | 1-CO2 |
| C. | 6-NADPH |
| D. | 2-Fructose -6-PO4 |
| Answer» C. 6-NADPH | |
| 13. |
Following organelles are involved in the formation of N-glycosylated product - |
| A. | Nucleolus |
| B. | SER |
| C. | Peroxisomes |
| D. | RER |
| Answer» E. | |
| 14. |
A nucleic acid was analyzed and found to contain 32% adenine, 18% guanine, 17% cytosine end 33% thymine.The nucleic acid must be - |
| A. | Double-stranded RNA |
| B. | Double-stranded DNA |
| C. | Single-stranded RNA |
| D. | Single-stranded DNA |
| Answer» C. Single-stranded RNA | |
| 15. |
Which of the following amino acids is involved in the synthesis of thyroxine - |
| A. | Threonine |
| B. | Tyrosine |
| C. | Glycine |
| D. | Methionine |
| Answer» C. Glycine | |
| 16. |
Acetyl CoA necessary for - |
| A. | Amino acid synthesis |
| B. | Fatty acid synthesis |
| C. | Glucose storage |
| D. | All of the above |
| Answer» C. Glucose storage | |
| 17. |
True about ATP synthase is all except - |
| A. | One rotation produce 3 ATP |
| B. | Alfa and Bita subunits roted |
| C. | Fo unit functions as proton channel |
| D. | All of the above |
| Answer» C. Fo unit functions as proton channel | |
| 18. |
An enzyme involved in the catabolism of fructose to pyruvate in the liver is: |
| A. | Lactate-dehydrogenase |
| B. | Glucokinase |
| C. | Glyceraldehyde-3-phosphate Dehydrogenase |
| D. | Phosphoglucomutase |
| Answer» D. Phosphoglucomutase | |
| 19. |
All biological active proteins are - |
| A. | L-forms |
| B. | D-forms |
| C. | Mostly D form |
| D. | D and L form |
| Answer» B. D-forms | |
| 20. |
The amino acid producing(major source of) ammonia in kidney is - |
| A. | Methionine |
| B. | Glycine |
| C. | Glutamine |
| D. | Alanine, Aspartate |
| Answer» D. Alanine, Aspartate | |
| 21. |
Which of the following factors is responsible for deciding whether an antibody/immunoglobulin will remain membrane bound or get secreted: |
| A. | Class Switching |
| B. | RNA Splicing |
| C. | Allelic Exclusion |
| D. | Differential RNA Processing |
| Answer» E. | |
| 22. |
One of the following mutation is potentially lethal -a) |
| A. | Substitution of guanine for cytosine |
| B. | Insertion of one base |
| C. | Substitution of adenine for cytosine |
| D. | Substitution of methycytosine for cytosine |
| Answer» C. Substitution of adenine for cytosine | |
| 23. |
Poly(A) tail translates into - |
| A. | Polylysine |
| B. | Polyproline |
| C. | Polyglycine |
| D. | Polylanine |
| Answer» B. Polyproline | |
| 24. |
In TCA cycle, citrate is covered into, after losing a molecule of H2O - |
| A. | Cis-aconitate |
| B. | Isocitrate |
| C. | Glutarate |
| D. | Oxaloacelate |
| Answer» B. Isocitrate | |
| 25. |
Pyrimidine synthesis rate limiting enzyme is ? |
| A. | Aspartate transcarbomylase |
| B. | Carbamoyl phosphate synthetase II |
| C. | Dihydro orotase dehydrogenase |
| D. | OMP. decarboxylase |
| Answer» C. Dihydro orotase dehydrogenase | |
| 26. |
Structural proteins are |
| A. | Fibrous |
| B. | Globular |
| C. | Branched |
| D. | Compound |
| Answer» B. Globular | |
| 27. |
Vitamin that is produced in the body: |
| A. | Thiamine |
| B. | Riboflavin |
| C. | Niacin |
| D. | Folate |
| Answer» D. Folate | |
| 28. |
Gene for major histocompatibility complex is located on: |
| A. | Long arm of chromosome 8 |
| B. | Short arm of chromosome 8 |
| C. | Long arm of chromosome 6 |
| D. | Short arm of chromosome 6 |
| Answer» E. | |
| 29. |
The primary structure of a protein refers to - |
| A. | Complete three-dimensional structure of the polypeptide units of a given protein |
| B. | Subunit structure of the protein |
| C. | Linear structure and order of the amino acids present |
| D. | Regular confirmational forms of a protein |
| Answer» D. Regular confirmational forms of a protein | |
| 30. |
Acidic amino acids are - |
| A. | Asparagine |
| B. | Arginine |
| C. | Lysine |
| D. | All of the above |
| Answer» B. Arginine | |
| 31. |
All of the following abbreviations are true except - |
| A. | GMP - Guanosine monophosphate |
| B. | TMP - Thymine monophosphate |
| C. | AMP - Adenosine monophosphate |
| D. | CMP - Cytidine monophosphate |
| Answer» C. AMP - Adenosine monophosphate | |
| 32. |
Test to differentiate in the chromosome of normal and cancer cells |
| A. | Comparative genomic hybridization |
| B. | PCR |
| C. | Southern Blotting |
| D. | Western Blotting |
| Answer» B. PCR | |
| 33. |
Detoxification of drugs is controlled by - |
| A. | Cytochrome P450 |
| B. | Cytochrome |
| C. | Cytochrome A |
| D. | Cytochrome C |
| Answer» B. Cytochrome | |
| 34. |
Amino acid secreted from muscles and producing glucose in liver: |
| A. | Glycine |
| B. | Valine |
| C. | Alanine |
| D. | Arginine |
| Answer» D. Arginine | |
| 35. |
A person on a fat free carbohtdrate rich diet continues to grow obese.Which of the following lipoproteins is likely to be elevated in his blood? |
| A. | VLDL |
| B. | Chylomicrons |
| C. | HDL |
| D. | LDL |
| Answer» B. Chylomicrons | |
| 36. |
Ischemia of the myocardium |
| A. | Increase in the resting membrane potential |
| B. | Decreases the resting membrane potential |
| C. | No change in RMP |
| D. | Alters the threshold potential |
| Answer» C. No change in RMP | |
| 37. |
Autosomal recessive disease are - |
| A. | Duchenne muscular dystrophy |
| B. | Tuberous sclerosis |
| C. | Factor VIII deficiency |
| D. | Cystic fibrosis |
| Answer» E. | |
| 38. |
Proteins are separated on the basis of size by - |
| A. | Affinity chromatography |
| B. | Ion-exchange chromatography |
| C. | SDS-PAGE |
| D. | HPLC |
| Answer» D. HPLC | |
| 39. |
An infant has hepatorenomegaly, hypoglycemia hyperlipidemia, acidosis and normal structured glycogen deposition in liver. what is the diagnosis - |
| A. | Von gierke's disease |
| B. | Her's disease |
| C. | Cori's disease |
| D. | Anderson's disease |
| Answer» B. Her's disease | |
| 40. |
Northern blot test is used for |
| A. | DNA analysis |
| B. | RNA analysis |
| C. | Analysis of proteins |
| D. | Enzyme analysis |
| Answer» C. Analysis of proteins | |
| 41. |
Glucose may be synthesised from: |
| A. | Guanine |
| B. | Palmitic acid |
| C. | Glycerol |
| D. | Adenine |
| Answer» D. Adenine | |
| 42. |
Glutamine in blood acts as - |
| A. | Stored energy |
| B. | Abnormal metabolite |
| C. | NH3 transporter |
| D. | Toxic element |
| Answer» D. Toxic element | |
| 43. |
After digestion by restriction endonucleases DNA strands can be joined again by- |
| A. | DNA ligase |
| B. | DNA polymerase |
| C. | DNA gyrase |
| D. | DNA topoisomerase |
| Answer» B. DNA polymerase | |
| 44. |
Antigen antiboey reaction is detected by - |
| A. | Northern blot |
| B. | Eastern blot |
| C. | FLISA |
| D. | Southern blot |
| Answer» C. FLISA | |
| 45. |
Defect in folding of the protein result in which of the following clinical disease - |
| A. | Hypothyroidism |
| B. | Myopia |
| C. | Kuru |
| D. | Migraine |
| Answer» D. Migraine | |
| 46. |
Amino acids secreted in cystinuria are all except- |
| A. | Ornithine |
| B. | Histidine |
| C. | Arginine |
| D. | Lysine |
| Answer» C. Arginine | |
| 47. |
Which of the following amino acids is involved in the synthesis of thyroxine |
| A. | Glycine |
| B. | Methionine |
| C. | Threortine |
| D. | Tyrosine |
| Answer» E. | |
| 48. |
Saturated aceyl enzyme formation causes - |
| A. | Freeing of PAN-SH site |
| B. | Freeing of Cyst-SH site |
| C. | Both |
| D. | None of the above |
| Answer» B. Freeing of Cyst-SH site | |
| 49. |
Which of the following statements regarding mature cytoplasmic messenger RNA is true: |
| A. | Sugar is DeoxyRibose |
| B. | Its molecular weight is more than hn-RNA |
| C. | Transcribed from Nuclear DNA |
| D. | Has Thiamine in place of Uracil |
| Answer» D. Has Thiamine in place of Uracil | |
| 50. |
Enzymes of Calvin cycle are - |
| A. | Sedoheptulose-1-7-bisphosphatase |
| B. | Glyceraldehyde 3-PO4 dehydrogenase |
| C. | Phosphoribulose kinase |
| D. | All of the above |
| Answer» E. | |