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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
About peptidyl transferase true is - |
| A. | Used in initiation and cause 43s complex formation |
| B. | Used in initiation and cause 48s complex formation |
| C. | Used in elongation and cause attachment of peptide chain to A-site of t RNA |
| D. | Used in elongation and cause attachment of peptide chain to P-site |
| Answer» D. Used in elongation and cause attachment of peptide chain to P-site | |
| 2. |
Inheritance of Familial Hypercholesterolemia is ? |
| A. | Autosomal resessive |
| B. | Autosomal dominant |
| C. | X-linked resessive |
| D. | X-linked dominant |
| Answer» C. X-linked resessive | |
| 3. |
The enzymes which increase or decrease in amount according to the need is called: |
| A. | Constitutive enzyme |
| B. | House keeping enzyme |
| C. | Allosteric enzyme |
| D. | Adaptive enzyme |
| Answer» E. | |
| 4. |
Glycosphingolipidis made up of - |
| A. | Glucose |
| B. | Sphingosine |
| C. | Fatty acids |
| D. | All of the above |
| Answer» E. | |
| 5. |
True about polymerase chain reaction - |
| A. | Carried out by thermostable DNA polymerase |
| B. | Exponential |
| C. | Specific |
| D. | All of the above |
| Answer» E. | |
| 6. |
Mitochondria is involved in all of the following,except: |
| A. | ATP production |
| B. | Apoptosis |
| C. | Tricarboxylic acid cycle |
| D. | Fatty acid biosynthesis |
| Answer» E. | |
| 7. |
Which of the following acts as cofactor after it's modification - |
| A. | Pantothenic acid |
| B. | Vit-C |
| C. | Copper |
| D. | Biotin |
| Answer» B. Vit-C | |
| 8. |
Which organs does not utilise ketone bodies - |
| A. | Skeletal muscles |
| B. | Cardiac muscles |
| C. | Liver |
| D. | Brain |
| Answer» D. Brain | |
| 9. |
The hydrolytic step leading to release of polypeptide chain from ribosomes in catalysed by - |
| A. | Stop codon |
| B. | Pepitidyl transferase |
| C. | AUG codon |
| D. | All of the above |
| Answer» C. AUG codon | |
| 10. |
The presence of 2 extra pairs of electrons on the oxygen in watere molecule results in: |
| A. | Makes water a non-polar solvent |
| B. | Forms covalent bonds in the ice |
| C. | Electro negative charge on water molecule |
| D. | Electro positive charge on water molecule |
| Answer» D. Electro positive charge on water molecule | |
| 11. |
Substrate level phosphorylation is seen in the conversion of: |
| A. | Succinyl CoA to Succinate |
| B. | Acetoacetate to a-keto glutarate |
| C. | Succinate to fumarate |
| D. | Fumarate to malate |
| Answer» B. Acetoacetate to a-keto glutarate | |
| 12. |
False positive test of protein in dipstick test seen in - |
| A. | IV administration of drugs |
| B. | IV contrast agent |
| C. | Vtral infection |
| D. | All of the above |
| Answer» C. Vtral infection | |
| 13. |
Substrate level phosphorylation in Glycolysis is seen in which step ? |
| A. | Glyceraldehyde 3 Phosphate dehydrogenase |
| B. | Pyruvate kinase |
| C. | Phosphofructokinase |
| D. | Enolase |
| Answer» C. Phosphofructokinase | |
| 14. |
True about translation of protein is - |
| A. | It has 3 steps initiation, elongation and termination |
| B. | IF-2 prevents reassociation of ribosomal subunit |
| C. | IF-3 and 1A cause binding of initiation codon |
| D. | All of the above |
| Answer» B. IF-2 prevents reassociation of ribosomal subunit | |
| 15. |
Sulphur containing amino acids are - |
| A. | Cysteine |
| B. | Asparagine |
| C. | Glycine |
| D. | All of the above |
| Answer» B. Asparagine | |
| 16. |
Which enzyme is active when insulin : Glucagon ratio is low - |
| A. | Glucokinase |
| B. | Hexo kinase |
| C. | Glucose-6-phosphatase |
| D. | Pyruvate carbosxylase |
| Answer» D. Pyruvate carbosxylase | |
| 17. |
A 10-year-old child with aggressive behavior and poor concentration is brought with presenting complaints of joint pain and reduced urinary output.Mother gives history of self mutilitative behavior stating that he tends to mutilate his fingers.Which of the following enzymes is likely to be deficient in this child? |
| A. | APRTase |
| B. | Acid Maltase |
| C. | HGPRTase |
| D. | Adenosin Deaminase |
| Answer» D. Adenosin Deaminase | |
| 18. |
Alpha oxidation of fatty acid takes place in ? |
| A. | ER |
| B. | Golgi apparatus |
| C. | Mitochondria |
| D. | Peroxisomes |
| Answer» E. | |
| 19. |
Bile acids are derived from |
| A. | Proteins |
| B. | Cholesterol |
| C. | Bilirubin |
| D. | Fatty acids |
| Answer» C. Bilirubin | |
| 20. |
Sequence in a long chain of protein is identified by - |
| A. | Restriction fragment length polymorphism(RFLP) |
| B. | Chromosome walking |
| C. | Leucine Zipper |
| D. | SSOP |
| Answer» C. Leucine Zipper | |
| 21. |
Wobble hypothesis - regarding the variation true is - |
| A. | 5 - end of anticodon |
| B. | 3 - end of anticodon |
| C. | t-RNA |
| D. | m-RNA |
| Answer» B. 3 - end of anticodon | |
| 22. |
Regarding Cytosolic Eukaryotic gene expression false is: |
| A. | Capping helps in attachment of mRNA to 40 S Ribosome |
| B. | N formyl methionine tRNA will be the first tRNA to come into action |
| C. | EF2 shifts between GDP and GTP |
| D. | Releasing factor releases the polypeptide chain from the P site. |
| Answer» C. EF2 shifts between GDP and GTP | |
| 23. |
Strongest bond amongst the following is |
| A. | Hydrophobic |
| B. | Electrostatic |
| C. | Hydrogen bond |
| D. | Wan der wall's |
| Answer» C. Hydrogen bond | |
| 24. |
All of the following statements about apoproteins are true Except: |
| A. | Apoprotein C-I activates lipoprotein lipase |
| B. | Apoprotein A-I activates LCAT |
| C. | Apoprotein C-II activates lipoprotein lipase |
| D. | Apoprotein C-II inhibits lipoprotein lipase |
| Answer» E. | |
| 25. |
UV ray causes: |
| A. | Single base pair change |
| B. | Triple base pair break |
| C. | DNA breakage |
| D. | Cross linkage |
| Answer» E. | |
| 26. |
True about enzyme specificity - |
| A. | Amount of enzyme binding with various substrates |
| B. | Amount of enzyme causing transformation of U mol of substrate per minute under standard conditions |
| C. | Amount of enzyme required per second, per mole or product formaton |
| D. | Number of sites per substrate |
| Answer» C. Amount of enzyme required per second, per mole or product formaton | |
| 27. |
The immediate precursor in the formation of acetoacetate from acetyl Co A in the liver is - |
| A. | HMG CoA |
| B. | Mevalonate |
| C. | 3-hydroxy-butyryl |
| D. | Acetoacetyl CoA |
| Answer» B. Mevalonate | |
| 28. |
What result due to incomplete oxidation of phenylpyruvic acid - |
| A. | Alkaptonuria |
| B. | Albinism |
| C. | Tyrosinemia |
| D. | Phenylketonuria |
| Answer» E. | |
| 29. |
True about IgM - |
| A. | Fix complement |
| B. | Increased in primary response |
| C. | Fab region is composed of variable region |
| D. | All of the above |
| Answer» E. | |
| 30. |
Starting material for production of insulin from bacteria is - |
| A. | Genomic DNA from beta pancreatic cells of human |
| B. | Genomic DNA from lymphocytes of human |
| C. | mRNA beta pancreatic cells of human |
| D. | mRNA from lymphocytes of human |
| Answer» D. mRNA from lymphocytes of human | |
| 31. |
Specific poison for succinate dehydrogenase is - |
| A. | Malonate |
| B. | Cyanide |
| C. | Fluoride |
| D. | Arsenite |
| Answer» B. Cyanide | |
| 32. |
In PCR Acquaticus thermophilus is preferred over E.coli. because - |
| A. | Done in more precisely |
| B. | Does not requier primer |
| C. | Thermostable at temperature at which DNA liquefies |
| D. | Proof reading one |
| Answer» D. Proof reading one | |
| 33. |
Thiamin requirement increases in excessive intake of |
| A. | Fat |
| B. | Lecithin |
| C. | Carbohydrates |
| D. | Amino acid |
| Answer» D. Amino acid | |
| 34. |
Oxaloacetate Acetyl CoA----- > Citrate CoASH This reaction is: |
| A. | Reversible |
| B. | Irreversible |
| C. | Can be reversed by catalase |
| D. | Competitive |
| Answer» C. Can be reversed by catalase | |
| 35. |
Bile salts are responsible for |
| A. | Protein digestion |
| B. | Fat digestion |
| C. | Bile secretion |
| D. | Calcium reabsorption |
| Answer» C. Bile secretion | |
| 36. |
Detergent action of bile salt is due to - |
| A. | Hydropathic |
| B. | Acts as a zwitter ion |
| C. | Amphipathic |
| D. | All of the above |
| Answer» D. All of the above | |
| 37. |
Leucine-Ziopper complex is - |
| A. | DNA binding protein |
| B. | Membrane attack complex |
| C. | B cell epitomes |
| D. | Receptor ligand protein |
| Answer» B. Membrane attack complex | |
| 38. |
Which of the following is a membrane bound enzyme that catalyzes the formation of cyclic AMP from ATP? |
| A. | ATP synthase |
| B. | Adenylate cyclase |
| C. | Tyrosine Kinase |
| D. | Polymerase |
| Answer» C. Tyrosine Kinase | |
| 39. |
In human body,the action of surfactant is done by- |
| A. | Sugar and salt |
| B. | Soap and water |
| C. | Lipid and protein |
| D. | Base and lipid |
| Answer» D. Base and lipid | |
| 40. |
The sigma subunit of prokaryotic RNA polymerase: |
| A. | Is inhibited by ALFA-amanitin |
| B. | Binds the antibiotic rifampicin |
| C. | Is part of the core enzyme |
| D. | Specifically recognizes the promoter site |
| Answer» E. | |
| 41. |
Increased levels of alanine in serum after fasting suggest - |
| A. | Increased released of alanine from muscle |
| B. | Reduce amino acid utilisation for gluconeogenesis |
| C. | Break in community of plasma membrane resulting in leakage of amino acids |
| D. | Decreased uptake of alanine by liver |
| Answer» B. Reduce amino acid utilisation for gluconeogenesis | |
| 42. |
The major of 2,3 bisphosphoglycerate in RBCs is ? |
| A. | Acid-base balance |
| B. | Reversal of glycolysis |
| C. | Release of Oxygen |
| D. | Binding of Oxygen |
| Answer» D. Binding of Oxygen | |
| 43. |
Which of the following is an example of reverse transcriptase ? |
| A. | Gyrase |
| B. | Helicase |
| C. | Telomerase |
| D. | RNA polymerase |
| Answer» D. RNA polymerase | |
| 44. |
Which one of the following enzymes use NADP as coenzyme - |
| A. | Lactate dehydrogenase |
| B. | Glyceraldehyde -3 phosphate dehydrogenase |
| C. | Beta hydroxy acyl CoA dehydrogenase |
| D. | Glucose -6- phosphate dehydrogenase |
| Answer» E. | |
| 45. |
NADPH is produced by - |
| A. | Citric acid cycle |
| B. | Glycolysis |
| C. | Glycogenesis |
| D. | Hexose monophosphate shunt |
| Answer» E. | |
| 46. |
In the following food items,which one has the highest 'Glycemic Index'? |
| A. | Corn-flakes |
| B. | Brown rice |
| C. | Ice-cream |
| D. | Whole wheat bread |
| Answer» B. Brown rice | |
| 47. |
A mutation in the codon which causes a change in the coded amino acid,is known as: |
| A. | Mitogenesis |
| B. | Somatic mutation |
| C. | Missense mutation |
| D. | Recombination |
| Answer» D. Recombination | |
| 48. |
TCA cycle and urea cycle is connected: |
| A. | Fumarate |
| B. | Malate |
| C. | Pyruvate |
| D. | Citrate |
| Answer» B. Malate | |
| 49. |
Site of proteins synthesis ? |
| A. | Nucleus |
| B. | Cytoplasm |
| C. | Peroxisomes |
| D. | Mitochondria |
| Answer» C. Peroxisomes | |
| 50. |
Which of the following lipoproteins does not move towards charged end in electrophoresis |
| A. | HDL |
| B. | Chylomicrons |
| C. | VLDL |
| D. | LDL |
| Answer» C. VLDL | |