MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Sequence of events glycogenolysis ? |
| A. | Transfearse, Phosphorylase, Debranching, Phosphorylase |
| B. | Any of the above |
| C. | Phosphorylase, glucan transfearse, Debranching, Phosphorylase |
| D. | Debranching, Phosphorylase, transfearse, Phosphorylase |
| Answer» D. Debranching, Phosphorylase, transfearse, Phosphorylase | |
| 2. |
An alfa helix of a protein is most likely to be disrupted if a missense mutation introduces the following amino acid with in the alpha helical structure |
| A. | Alamine |
| B. | Aspartic acid |
| C. | Tyrosine |
| D. | Glycine |
| Answer» C. Tyrosine | |
| 3. |
Ultrviolet absorption is maximum for |
| A. | Tryptophan |
| B. | Alanine |
| C. | Lysine |
| D. | Aspartic acid |
| Answer» B. Alanine | |
| 4. |
Negative nitrogen balance is produced in humans by elimination from the diet of all of the following amino acids except - |
| A. | Lysine |
| B. | Serine |
| C. | Leucine |
| D. | Methionine |
| Answer» C. Leucine | |
| 5. |
Difference between High mannose and complex glycoprotein - |
| A. | Asparagine |
| B. | Presence of GIC - NAc - Gal - NANA in complex glycoprotein |
| C. | Core pentasacharide |
| D. | Protein chain |
| Answer» C. Core pentasacharide | |
| 6. |
Okazaki segments are required for: |
| A. | DNA synthesis |
| B. | RNA synthesis |
| C. | Protein synthesis |
| D. | None of the above |
| Answer» B. RNA synthesis | |
| 7. |
Co-factor of Carbonic anhydrase is ? |
| A. | Molybdenum |
| B. | Zinc |
| C. | Copper |
| D. | Selenium |
| Answer» C. Copper | |
| 8. |
Which enzyme involved in translation is often referred to as 'Fidelity enzyme': |
| A. | RNA polymerase |
| B. | DNA polymerase |
| C. | Amino acyl-reductase |
| D. | Amino acyl-t RNA synthetase |
| Answer» E. | |
| 9. |
All are true of the genetic code except - |
| A. | Universal |
| B. | Punctuation |
| C. | Degenerate |
| D. | Non overlapping |
| Answer» C. Degenerate | |
| 10. |
Replacing alanine by which amino acid will increase UV absorbance of protein at 280 nm wavelength? |
| A. | Arginine |
| B. | Tryptophan |
| C. | Leucine |
| D. | Proline |
| Answer» C. Leucine | |
| 11. |
Farber,s disease is due to the deficiency of - |
| A. | Ceraminidase |
| B. | Sphingomyelinase |
| C. | Glucocerebrosidase |
| D. | Neuraminidase |
| Answer» B. Sphingomyelinase | |
| 12. |
Which of the following side chains is least polar |
| A. | Amino |
| B. | Phosphate |
| C. | Methyl |
| D. | Carboxyl |
| Answer» D. Carboxyl | |
| 13. |
True about cell membrane permeability- |
| A. | Water and electrolytes are freely permeable |
| B. | Fat soluble substances are freely permeable |
| C. | Water soluble substances are freely permeable |
| D. | Impermeable to all |
| Answer» C. Water soluble substances are freely permeable | |
| 14. |
The conjugation of bilirubin to glucuronic acid in the liver - |
| A. | Converts a hydrophilic compound to hydrophilic one |
| B. | Converts a hydrophilic compound to hydrophobic one |
| C. | Is increased during neonatal jaundice |
| D. | Enables the bilirubin molecule to cross the cell membrane |
| Answer» B. Converts a hydrophilic compound to hydrophobic one | |
| 15. |
At physiological pH buffering action in blood is caused by - |
| A. | Hemocysteine |
| B. | Glycine |
| C. | Histidine |
| D. | Methionine |
| Answer» D. Methionine | |
| 16. |
Maximum influence of local milieu on ionization is on - |
| A. | Glycine |
| B. | Lysine |
| C. | Histidine |
| D. | Protine |
| Answer» D. Protine | |
| 17. |
Which of the following statement characterize both Hemoglobin and Myoglobin - |
| A. | Binds with 2 Heme |
| B. | Heme at hydrophobic pockets |
| C. | Non-helical |
| D. | Subunits which are held together by hydrogen bonds |
| Answer» C. Non-helical | |
| 18. |
P50 is increased by decrease of ? |
| A. | CO2 |
| B. | Body temperature |
| C. | pH |
| D. | 2,3 DPG |
| Answer» D. 2,3 DPG | |
| 19. |
Rate limiting step in bilirubin metabolism- |
| A. | Conjugation of bilirubin with glucuronic acid |
| B. | Heme oxygenase |
| C. | Uptake of bilirubin by hepatocyte |
| D. | Secretion of conjugated bilirubin into the bile |
| Answer» E. | |
| 20. |
Vitamin B12 and folic acid supplementation in megaloblastic anemia leads to the improvement of anemia due to: |
| A. | Erythroid hyperplasia |
| B. | Increased iron absorption |
| C. | Increased DNA synthesis in bone marrow |
| D. | Increased Hemoglobin production |
| Answer» D. Increased Hemoglobin production | |
| 21. |
Dietary fibre contains: |
| A. | Collagen |
| B. | Pectin |
| C. | Proteoglycans |
| D. | Starch |
| Answer» C. Proteoglycans | |
| 22. |
Neuropathy and cataract in diabetic patients are believed to result from accumulation of |
| A. | Glucose |
| B. | Fructose |
| C. | Glycosylated hemoglobin |
| D. | Sorbitol |
| Answer» E. | |
| 23. |
The comparison of the amino acid sequence of Cytochrome C from different species shows many variations.Most of these variations are found: |
| A. | Only in strand regions |
| B. | Mainly in loop regions |
| C. | Randomly |
| D. | Only in helical regions |
| Answer» D. Only in helical regions | |
| 24. |
First substrate of Kreb's cycle is - |
| A. | HCL |
| B. | Lipoprotein |
| C. | Pyruvate |
| D. | Glycine |
| Answer» D. Glycine | |
| 25. |
Alkaline phosphatase is produced by |
| A. | Liver |
| B. | Bone |
| C. | Placenta |
| D. | All of the above |
| Answer» E. | |
| 26. |
Lesch Nyhan syndrome is due to deficiency of - |
| A. | Purine phosphorylase |
| B. | Adenosine deaminase |
| C. | Hypoxanthine phosphoribosyl transferase |
| D. | Xanthine oxidase |
| Answer» D. Xanthine oxidase | |
| 27. |
Thiamine is not used in which of the following reactions |
| A. | Lactate to pyruvate |
| B. | Alphaketoglutarate to succinyl CoA |
| C. | Glucose to pentose |
| D. | Oxidative decarboxylation of alpha keto amino acids |
| Answer» B. Alphaketoglutarate to succinyl CoA | |
| 28. |
True about 'X' Chromosome inactivation - |
| A. | X gene |
| B. | RNA interference |
| C. | Seen in Male |
| D. | All of the above |
| Answer» B. RNA interference | |
| 29. |
Most stable amino acid at the physiological pH is |
| A. | Histidine |
| B. | Lysine |
| C. | Arginine |
| D. | Glycine |
| Answer» B. Lysine | |
| 30. |
Intact peptide bond is necessary for which test - |
| A. | UV diffraction |
| B. | Ninhydrin |
| C. | Diazo reaction |
| D. | All of the above |
| Answer» C. Diazo reaction | |
| 31. |
Test for ketone bodies is: |
| A. | Benedict's test |
| B. | Hay's test |
| C. | Rothera's test |
| D. | Salinawoff test |
| Answer» D. Salinawoff test | |
| 32. |
False about hereditary fructose intolerance is - |
| A. | Accumulation of fructose 1- phosphate tissue |
| B. | Deficiency of fructose 1- phosphate aldolase |
| C. | Liver and kidneys are involved |
| D. | Hyperglycemia |
| Answer» E. | |
| 33. |
A hypothetical gene contains coding strand of 5' -TGGAATTGTATG-3. What would be the sequence of the resultant mRNA following transcription ? |
| A. | 3' - ACCTTAACATAC - 5' |
| B. | 5' - ACCUUAACAUAC -3' |
| C. | 5' - UGGAAUUGUAUG - 3' |
| D. | 3' - UCCTTUUCAUAC - 5' |
| Answer» D. 3' - UCCTTUUCAUAC - 5' | |
| 34. |
Karyotyping under light microscopy is done by - |
| A. | Q banding |
| B. | R banding |
| C. | C banding |
| D. | G banding |
| Answer» E. | |
| 35. |
All of the following statements about Lambda phage are true,Except: |
| A. | In Lytic phase it fuses with host Chromosomes and replicates |
| B. | In Lysogenic phase it fuses with host chromosome and remains dormant |
| C. | In Lytic phase it causes cell lysis and releases virus particles |
| D. | Both Lytic and Lysogenic phases occur together |
| Answer» E. | |
| 36. |
Of the following groups of amino acids produce common component of the TCA cycle is - |
| A. | Serine, asparagines, glycine, glutamate |
| B. | Alaine, isoleucine, leucine, lysine |
| C. | Prolane, leucine, tryptophan |
| D. | Isoleucine, valine, methionine |
| Answer» E. | |
| 37. |
Protein that precipitates on heating to 450C and redissolves on boiling is: |
| A. | Bence Jones Protein |
| B. | Gamma globulin |
| C. | Albumin |
| D. | Myosin |
| Answer» B. Gamma globulin | |
| 38. |
Active form of vitamin D is - |
| A. | 24, 25 (OH)2 vit-D |
| B. | Cholecalciferol |
| C. | 25-OH vit-D |
| D. | 1,25 (OH)2 vit-D |
| Answer» E. | |
| 39. |
Detergent action of bile salts is due to - |
| A. | Hydropathic |
| B. | Acts as a zwitter ion |
| C. | Amphipathic |
| D. | All of the above |
| Answer» D. All of the above | |
| 40. |
Cholesterol is transported to extrahepatic tissues by - |
| A. | HDL |
| B. | LDL |
| C. | IDL |
| D. | VLDL |
| Answer» C. IDL | |
| 41. |
Some aminoacid is codded by multiple codons d/t folloing - |
| A. | Transcription |
| B. | Mutation |
| C. | Degeneracy |
| D. | Frame-shift mutation |
| Answer» D. Frame-shift mutation | |
| 42. |
All are statements regarding LDL receptors are true except - |
| A. | Present only in the extra-hepatic tissues |
| B. | Clathrin-coated pits contain the receptor on cell membrane |
| C. | It is taken into the cells by endocytosis |
| D. | Increased cellular cholesterol down-regulates the synthesis of LDL receptors |
| Answer» B. Clathrin-coated pits contain the receptor on cell membrane | |
| 43. |
Function of Metabolism includes all except |
| A. | Extraction of nutrients from food |
| B. | Breakdown of substrate |
| C. | Equilibrium of biochemical with intracellular components |
| D. | Using building blocks for synthesis |
| Answer» B. Breakdown of substrate | |
| 44. |
Chymotrypsinogen is a - |
| A. | Transaminase |
| B. | Carboxypeptidase |
| C. | Elastase |
| D. | Zymogen |
| Answer» E. | |
| 45. |
Non Polar Amino Acids are - |
| A. | Alanine |
| B. | Tryptophan |
| C. | Isoleucine |
| D. | All of the above |
| Answer» E. | |
| 46. |
All of the following statements are true regarding lipoproteins except: |
| A. | LDL transports lipids to the tissues |
| B. | VLDL transports endogenous lipids |
| C. | Increased HDL is associated with decreased risk of coronary disease |
| D. | Increased blood cholesterol is associated with increased LDL receptors |
| Answer» E. | |
| 47. |
A transporter has a Km for glucose of 45 mM and a V max of 36 micro-moles glucose sec/mg of transporter. If the glucose concentration in peripheral blood is 15 mM, what will the rate of glucose transport (in micro-moles glucose/sec/mg transporter) be ? |
| A. | 6 |
| B. | 3 |
| C. | 12 |
| D. | 9 |
| Answer» D. 9 | |
| 48. |
Intermediate metabolic in TCA cycle are A/E - |
| A. | Pyruvate |
| B. | Malonate |
| C. | Nitric oxide |
| D. | All of the above |
| Answer» E. | |
| 49. |
All of the following are true regarding DNA except: |
| A. | Coplementary base pairing present |
| B. | Antiparallel chain |
| C. | Hydrogen bond connects adenine with thymine and guanine with cytosine |
| D. | Ribonucleoprotein is present |
| Answer» E. | |
| 50. |
After overnight facing,levels of glucose tranporters reduced in: |
| A. | RBCs |
| B. | Brain cells |
| C. | Hepatocytes |
| D. | Adipocytes |
| Answer» E. | |