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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Treatment of Multiple Carboxylase Deficiency is: |
| A. | Biotin |
| B. | Pyridoxine |
| C. | Thiamine |
| D. | Folic acid |
| Answer» B. Pyridoxine | |
| 2. |
The main enzyme responsible for activation of xenobiotics is |
| A. | NADPH cytochrome P-450-reductase |
| B. | Glucuronyl transferase |
| C. | Cytochrome P-450 |
| D. | Glutathione S-transferase |
| Answer» D. Glutathione S-transferase | |
| 3. |
RBC membrane is maintained by: |
| A. | Spectrin |
| B. | Laminin |
| C. | Collagen |
| D. | Elastin |
| Answer» B. Laminin | |
| 4. |
A mutation in the codon which causes a change in the coded amino acid, is known as - |
| A. | Somatic mutation |
| B. | Mitogenesis |
| C. | Recombination |
| D. | Missence mutation |
| Answer» E. | |
| 5. |
If a 4 nucleotide sequence code for an amino acid instead of 3, then theoretically how many unique amino acids could be code by such a system ? |
| A. | 16 |
| B. | 64 |
| C. | 128 |
| D. | 256 |
| Answer» E. | |
| 6. |
The first step in fatty acid synthesis involves |
| A. | Acetyl CoA carboxylase |
| B. | Beta Hydroxyl CoA dehydrogenase |
| C. | Acetyl dehydrogenase |
| D. | Pyruvate kinase |
| Answer» B. Beta Hydroxyl CoA dehydrogenase | |
| 7. |
Proteins targeted for destruction in eukaryotes are covalently linked to: |
| A. | Laminin |
| B. | Ubiquitin |
| C. | Clathrin |
| D. | Pepsin |
| Answer» C. Clathrin | |
| 8. |
Acetyl coA can be directly converted to all except |
| A. | Cholesterol |
| B. | Ketone bodies |
| C. | Glucose |
| D. | Fatty acids |
| Answer» D. Fatty acids | |
| 9. |
Which of the following is increased in lipoprotein lipase deficiency |
| A. | VLDL |
| B. | LDL |
| C. | HDL |
| D. | Chylomicrons |
| Answer» E. | |
| 10. |
Which of an allosteric protein - |
| A. | Phosphofructokinase |
| B. | Heamoglobin |
| C. | Transferrin |
| D. | Ceruloplasmin |
| Answer» C. Transferrin | |
| 11. |
The attachment site of DNA dependent RNA polymerase to a gene is the - |
| A. | Promoter |
| B. | Operator |
| C. | Regulatory gene |
| D. | Structural gene |
| Answer» B. Operator | |
| 12. |
True about isoenzymes is - |
| A. | Same quaternary structure |
| B. | Same distribution in different organs |
| C. | Same enzyme classification with same numbers |
| D. | Catalyze the same reaction |
| Answer» E. | |
| 13. |
Melatonin is synthesised from - |
| A. | Phenylalanine |
| B. | Histidine |
| C. | Tryprophan |
| D. | Serotonin |
| Answer» D. Serotonin | |
| 14. |
What is meant by melting of double stranded DNA - |
| A. | Splitting of double strands into single strands |
| B. | Splitting of DNA into fragments |
| C. | Formation of triple helix |
| D. | Separation of bases |
| Answer» B. Splitting of DNA into fragments | |
| 15. |
Which one of the following vitamins has antioxidant property ? |
| A. | Vitamin K |
| B. | Vitamin C |
| C. | Vitamin D |
| D. | Vitamin B |
| Answer» C. Vitamin D | |
| 16. |
Membrane integrity of RBC is due to - |
| A. | G-protein |
| B. | Haemoglobin |
| C. | Spectrin |
| D. | Ankyrin |
| Answer» D. Ankyrin | |
| 17. |
In starvation, nitrogen is carried from muscle to liver and kidney by - |
| A. | Glycine |
| B. | Asparagines |
| C. | Alanine |
| D. | Aspartic acid and Serine |
| Answer» D. Aspartic acid and Serine | |
| 18. |
Hemoglobin is a buffer because of - |
| A. | Weak acidic nature |
| B. | Iron molecule |
| C. | Histidine residue |
| D. | Glycoprotein nature |
| Answer» D. Glycoprotein nature | |
| 19. |
Enzyme replacement therapy can be done in: |
| A. | Gaucher's disease |
| B. | Nieman-Pick's disease |
| C. | Tay-Sach's disease |
| D. | Krabbe's disease |
| Answer» B. Nieman-Pick's disease | |
| 20. |
Coenzymes are....organic compounds - |
| A. | Lipoprotein |
| B. | Proteinaceous |
| C. | Non-protein |
| D. | All of the above |
| Answer» D. All of the above | |
| 21. |
In a DNA the coding region reads 5'-CGT-3'.This would code in the RNA as: |
| A. | 5'-CGU-3' |
| B. | 5'-GCA-3' |
| C. | 5'-ACG-3' |
| D. | 5'-UGC-3' |
| Answer» B. 5'-GCA-3' | |
| 22. |
In which package form dietary fat is |
| A. | Free fatty acid |
| B. | Monoacyl glycerol |
| C. | Chylomicron |
| D. | Micelles |
| Answer» E. | |
| 23. |
Fluorescence means - |
| A. | Spontaneous illumination indark |
| B. | Release of longer wavelength light on absorbing light on shorter wavelength |
| C. | Release of shorter wavelength light on absorbing light on longer wavelength |
| D. | Release on equal wavelength light on constant rate |
| Answer» C. Release of shorter wavelength light on absorbing light on longer wavelength | |
| 24. |
Concentration of DNA is measured by - |
| A. | Infrared examination |
| B. | Ultrasound examination |
| C. | Absorption at 260 nm |
| D. | D-oxyribose estimation |
| Answer» D. D-oxyribose estimation | |
| 25. |
After 50 gm glucose is feed orally - |
| A. | Increased lactate production upon exercise |
| B. | Decrease ketone body production |
| C. | Increased gluconeogenesis |
| D. | Decreased gluconeogenesis |
| Answer» E. | |
| 26. |
Gene for major histocompatibility complex is located on - |
| A. | Long arm of chromosome 6 |
| B. | Short arm of chromosome 6 |
| C. | Long arm of chromosome 8 |
| D. | Short arm of chromosome 8 |
| Answer» C. Long arm of chromosome 8 | |
| 27. |
Which among the following is not an example of a steroid hormone ? |
| A. | Aldosterone |
| B. | Testosterone |
| C. | Thyroxine |
| D. | Cortisol |
| Answer» D. Cortisol | |
| 28. |
Which of these is a conservative mutator - |
| A. | Histidine - glycine |
| B. | Glutamic acid - glutamine |
| C. | Arginine - aspartic acid |
| D. | Alanine - Leucine |
| Answer» E. | |
| 29. |
Nothern blot is used for the separation of: |
| A. | mRNA |
| B. | DNA |
| C. | Protein |
| D. | Protein DNA interaction |
| Answer» B. DNA | |
| 30. |
Which of the following does not undergo phosphorylation by protein kinase in Eukaryotes: |
| A. | Serine |
| B. | Asparagine |
| C. | Threonine |
| D. | Tyrosine |
| Answer» C. Threonine | |
| 31. |
Vit. K is needed for which of these transational modification process - |
| A. | Carboxylation |
| B. | Methylation |
| C. | Transketolation |
| D. | Hydroxylation |
| Answer» B. Methylation | |
| 32. |
Peroxidase enzyme is used in estimating - |
| A. | Creatinine |
| B. | Glucose |
| C. | Haemoglobin |
| D. | Ammonia |
| Answer» C. Haemoglobin | |
| 33. |
In a mutation if valine is replaced by which of the following would not result in any change in the function of protein - |
| A. | Glycine |
| B. | Aspartic acid |
| C. | Proline |
| D. | Leucine |
| Answer» C. Proline | |
| 34. |
True regarding electrophoresis are all except - |
| A. | Adversly affect structure and function |
| B. | Isoelectric focusing use ampholytes and pI |
| C. | Use electric field and quickly estimate no. of proteins |
| D. | Depends on size not on shape |
| Answer» E. | |
| 35. |
Northern bolt test is used for - |
| A. | RNA analysis |
| B. | DNA analysis |
| C. | Enzyme analysis |
| D. | Analysis of proteins |
| Answer» B. DNA analysis | |
| 36. |
NO is synthesized by |
| A. | Guanodine |
| B. | Arginine |
| C. | Uracil |
| D. | Aspartate |
| Answer» C. Uracil | |
| 37. |
Aminoacid containing indole ring is - |
| A. | Tryptophan |
| B. | Arginine |
| C. | Histidine |
| D. | Tyrosine |
| Answer» B. Arginine | |
| 38. |
Following constitute dietary fibres except: |
| A. | Hemicellulose |
| B. | Riboflavin |
| C. | Pectine |
| D. | Cellulose |
| Answer» C. Pectine | |
| 39. |
Which process separates the fragments of DNA - |
| A. | High speed centrifugation |
| B. | Thin layer chromatography |
| C. | Gel centrifugation |
| D. | Paper chromatography |
| Answer» D. Paper chromatography | |
| 40. |
Nucleosome consists of - |
| A. | DNA and RNA both |
| B. | Carbohydrate |
| C. | Histone |
| D. | RNA |
| Answer» D. RNA | |
| 41. |
Mallate shuttle is seen to occur in: |
| A. | HMP shunt |
| B. | Gluconeogenesis |
| C. | Glycolysis |
| D. | Glycogenolysis |
| Answer» D. Glycogenolysis | |
| 42. |
Reverse transcription involve conversion of: |
| A. | --RNA -->DNA |
| B. | --DNA -->RNA |
| C. | --DNA-->Protein |
| D. | --RNA -->Protein |
| Answer» B. --DNA -->RNA | |
| 43. |
Increased copper excretion in urine is seen in all except - |
| A. | Primary biliary cirrhosis |
| B. | Hepatocellular carcinoma |
| C. | Primary sclerosing cholangitis |
| D. | Wilson's disease |
| Answer» C. Primary sclerosing cholangitis | |
| 44. |
Hemoglobin acts as buffer because of - |
| A. | Histidine |
| B. | Glycine |
| C. | Valine |
| D. | Alanine |
| Answer» B. Glycine | |
| 45. |
Fireflies produce light due to |
| A. | GTP |
| B. | NADH |
| C. | Phosphocreatinine |
| D. | ATP |
| Answer» E. | |
| 46. |
The two strands of DNA are held together by - |
| A. | Van-der-Wall bond |
| B. | Hydrogen bond |
| C. | Covelent bond |
| D. | Ionic interaction |
| Answer» C. Covelent bond | |
| 47. |
True about polymerase chain reaction is: |
| A. | Separation of protein fragments is serum |
| B. | None |
| C. | Enzymatic DNA amplification |
| D. | Recombinent DNA amplification |
| Answer» D. Recombinent DNA amplification | |
| 48. |
All of the following can determine the protein structure, except |
| A. | X-ray crystallography |
| B. | NMR spectrometry |
| C. | High performance liquid chromatography |
| D. | Mass spectrometry |
| Answer» D. Mass spectrometry | |
| 49. |
Transition temperature of lipid bilayers of cell membrane is increased by- |
| A. | Cholesterol |
| B. | Saturated fatty acids |
| C. | Hydrocarbons |
| D. | Unsaturated fatty acids |
| Answer» C. Hydrocarbons | |
| 50. |
Which of the following estimates blood creatinine level most accurately - |
| A. | Technicon method |
| B. | Enzyme assay |
| C. | Jaffe method |
| D. | Kinetic jaffe method |
| Answer» D. Kinetic jaffe method | |