MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In maple syrup urine disease the amino acids. excreted in the urine are - |
| A. | Leucine |
| B. | Isoleucine |
| C. | Valine |
| D. | All of the above |
| Answer» E. | |
| 2. |
The following hormone does not have any intracellular receptor |
| A. | Vitamin D3 |
| B. | Cortisone |
| C. | Adrenaline |
| D. | Thyroxine |
| Answer» D. Thyroxine | |
| 3. |
Steroid hormone receptors have attachment site for all except - |
| A. | Transcription repressors |
| B. | Steroid hormone |
| C. | Transcription activators |
| D. | Hormone responsive element |
| Answer» B. Steroid hormone | |
| 4. |
For reducing of cholesterol, the best management includes - |
| A. | Diet with high unsaturated FA and low saturaed FA |
| B. | Cholesterol restricted diet, high fever and diet with low saturaed FA to unsaturated FA ratio |
| C. | Cholesterol restricted diet |
| D. | High fever diet |
| Answer» C. Cholesterol restricted diet | |
| 5. |
mRNA is a complimentary copy of - |
| A. | Ribosomal DNA |
| B. | A single strand of DNA |
| C. | TRNA |
| D. | RRNA |
| Answer» C. TRNA | |
| 6. |
Neutral molecules are transported by |
| A. | Porin channels |
| B. | Ionophores |
| C. | Simple Diffusion |
| D. | None of the above |
| Answer» D. None of the above | |
| 7. |
An alfa helix of a protein is most likely to be disrupted if a missense mutation introdues the following amino acid with in the alpha helical structure - |
| A. | Aspartic acid |
| B. | Alanine |
| C. | Glycine |
| D. | Tyrosine |
| Answer» B. Alanine | |
| 8. |
In glycolytic pathway, products formed are - |
| A. | Fructose 2,6-Biphosphate |
| B. | Fructose 1,6-Biphosphate |
| C. | Glyceraldehyde-3-Phosphate |
| D. | All of the above |
| Answer» E. | |
| 9. |
Rate limiting enzyme in the synthesis of cholesterol is |
| A. | HmG CoA reductase |
| B. | HmG CoA synthetase |
| C. | Acetyl CoA synthetase |
| D. | Acetyl CoA carboxylase |
| Answer» B. HmG CoA synthetase | |
| 10. |
At the physiological ph the DNA molecules are |
| A. | Positively charged |
| B. | Negatively charged |
| C. | Neutral |
| D. | Amphipathic |
| Answer» C. Neutral | |
| 11. |
Hydroxyethyl starch is a |
| A. | Vasodilator |
| B. | Inotrope |
| C. | Plasma expander |
| D. | Diuretic |
| Answer» D. Diuretic | |
| 12. |
Which of the following is true about glutathione - |
| A. | Contain sulfhydral group |
| B. | Transport aminoacid across cell membrane |
| C. | Part of enzyme |
| D. | All of the above |
| Answer» E. | |
| 13. |
Patient present with skin bullae on sun exposure. The defect is of? |
| A. | Sugar changes |
| B. | DNA methylation |
| C. | Thymidine dimmers |
| D. | Trinucleotide repeats |
| Answer» C. Thymidine dimmers | |
| 14. |
Random arrangement of molecule result in - |
| A. | Crystallization |
| B. | Denaturation |
| C. | High solubility |
| D. | All of the above |
| Answer» C. High solubility | |
| 15. |
Which is true for glucoronidation ? |
| A. | Water solubility decreased |
| B. | Phase II reaction |
| C. | Phase I reaction |
| D. | Done by CYP enzymes |
| Answer» C. Phase I reaction | |
| 16. |
Conversion of glycine to serine requires - |
| A. | Vit. C |
| B. | Pyridoxal phosphate |
| C. | Folic acid |
| D. | Thiamine |
| Answer» D. Thiamine | |
| 17. |
In cytochrom P-450, P stands for: |
| A. | Substrate protein |
| B. | Pigment |
| C. | Structural protein |
| D. | Polymer |
| Answer» C. Structural protein | |
| 18. |
True about Ig gene rearrangement and Ig diversity - |
| A. | Somatic mutations theory |
| B. | DNA rearrangement |
| C. | Appropriate class switching |
| D. | All of the above |
| Answer» E. | |
| 19. |
Prenatal diagnosis of Hemophilia is best done by |
| A. | Cytometry |
| B. | Microarray |
| C. | PCR |
| D. | Linkage analysis |
| Answer» D. Linkage analysis | |
| 20. |
Protein is purified using ammonium sulfate by |
| A. | Mass chromatography |
| B. | Molecular size exclusion |
| C. | Salting out |
| D. | Ion exchange chromatography |
| Answer» D. Ion exchange chromatography | |
| 21. |
Sulphur containing amino acid is/are - |
| A. | Glutamine |
| B. | Aspartic acid |
| C. | Glycine |
| D. | Methionine |
| Answer» E. | |
| 22. |
Which of the following is not synthesised from tyrosine - |
| A. | Melatonin |
| B. | Norepinephrine |
| C. | Dopamine |
| D. | Thyroxine |
| Answer» B. Norepinephrine | |
| 23. |
All of the following are essential aminoacids except - |
| A. | Lysine |
| B. | Methionine |
| C. | Leucine |
| D. | Alanine |
| Answer» E. | |
| 24. |
Refsums disease is due to deficiency of which of the following enzyme? |
| A. | Succinate thiokinase |
| B. | Phytanic alpha oxidase |
| C. | Malonate dehydrogenase |
| D. | Thiophorase |
| Answer» C. Malonate dehydrogenase | |
| 25. |
The substance from which ammonia is produce by the kidney is - |
| A. | Alanine |
| B. | Glycine |
| C. | Methionine |
| D. | Glutamine |
| Answer» E. | |
| 26. |
Which of the following anticoaguatant used in estimating blood glucose prevents glycolysis - |
| A. | Citrate |
| B. | Oxalate |
| C. | Heparin |
| D. | NaF |
| Answer» E. | |
| 27. |
NADPH is used in |
| A. | Fatty acid synthesis |
| B. | Ketone synthesis |
| C. | Gluconeogenesis |
| D. | Glycolysis |
| Answer» B. Ketone synthesis | |
| 28. |
DNA fragments formed by the action of Restriction Endonucleases,are separated by: |
| A. | Paper Chromatography |
| B. | High pressure liquid Chromatography |
| C. | Gel electrophoresis |
| D. | Agarose gel electrophoresis |
| Answer» D. Agarose gel electrophoresis | |
| 29. |
Pyruvate dehydrogenase complex has all enzyme components except - |
| A. | Dehydrogenase |
| B. | Phosphatase |
| C. | Decarboxylase |
| D. | Transcetylase |
| Answer» C. Decarboxylase | |
| 30. |
Von-Gierke's disease is due to deficiency of - |
| A. | Muscle glycogen phosphorylase |
| B. | Liver glycogen phosphorylase |
| C. | Glucose - 6- Phosphatase |
| D. | Debranching enzyme |
| Answer» D. Debranching enzyme | |
| 31. |
Pentosuria is due to defect in which pathway ? |
| A. | Glycolysis |
| B. | Polyo pathway |
| C. | Uronic acid apthway |
| D. | Kreb's cycle |
| Answer» D. Kreb's cycle | |
| 32. |
Fluroide ions act by inhibiting - |
| A. | Cytochrome oxidase |
| B. | Carbonic anydrase |
| C. | Enolase |
| D. | Hexokinase |
| Answer» D. Hexokinase | |
| 33. |
A small Ca+2 binding protein that modifies the activity of many enzymes and other proteins in response to changes of Ca2concentration,is known as: |
| A. | Calmodulin |
| B. | Cycline |
| C. | Kinesin |
| D. | Collagen |
| Answer» B. Cycline | |
| 34. |
Amino acid involve in 1 carbon metabolism - |
| A. | Folic acid |
| B. | Thiamine |
| C. | Pyridoxine |
| D. | All of the above |
| Answer» B. Thiamine | |
| 35. |
True about competitive inhibitions is ? |
| A. | Increases VMax |
| B. | Increased KM |
| C. | Decreased VMax |
| D. | Decreased KM |
| Answer» C. Decreased VMax | |
| 36. |
Shine-Dalgarno sequence in bacterial mRNA is near: |
| A. | UAG codon |
| B. | UGA codon |
| C. | AUG codon |
| D. | UAA codon |
| Answer» D. UAA codon | |
| 37. |
Amino acids secreted in cystinuria are all except - |
| A. | Histidine |
| B. | Ornithine |
| C. | Lysine |
| D. | Arginine |
| Answer» B. Ornithine | |
| 38. |
In starvation,nitrogen is carried from muscle to liver and kidney by: |
| A. | Alanine |
| B. | Glycine |
| C. | Asparagines |
| D. | Aspartic acid and Serine |
| Answer» B. Glycine | |
| 39. |
True about 2,4-Dinitrophenol is ? |
| A. | Prevents ATP synthesis and Electron transport chain |
| B. | Prevents ATP synthesis but Electron transport chain is increased |
| C. | Blocks electron transport chain but ATP synthesis is normal |
| D. | Blocks ATP synthesis but electron transport chain is normal |
| Answer» C. Blocks electron transport chain but ATP synthesis is normal | |
| 40. |
At the physiological pH the DNA molecules are - |
| A. | Neagitively charged |
| B. | Positively charged |
| C. | Amphipathic |
| D. | Neutral |
| Answer» B. Positively charged | |
| 41. |
Fatty acid entry into mitochondria requires - |
| A. | Fatty acid binding protein |
| B. | Carnitine |
| C. | Creatine |
| D. | Creatinine |
| Answer» C. Creatine | |
| 42. |
An vivo control of citric acid cycle is effected by - |
| A. | Coenzyme A |
| B. | Acetyl CoA |
| C. | Citrate |
| D. | ATP |
| Answer» E. | |
| 43. |
Among the following the maximum redox potential is for - |
| A. | Ubiquinone |
| B. | Fe+3 / Fe+2 |
| C. | NADH/NAD |
| D. | Succinate / Fumarate |
| Answer» C. NADH/NAD | |
| 44. |
Chylomicrons core is formed by ? |
| A. | Triglyceride and Cholesterol |
| B. | Triglyceride and Cholesterol |
| C. | Triglyceride, Cholesterol and Phospholipids |
| D. | Free fatty acids |
| Answer» C. Triglyceride, Cholesterol and Phospholipids | |
| 45. |
Km value defined as - |
| A. | Substrate concentration of thrice Vmax |
| B. | Substrate concentration of one third Vmax |
| C. | Substrate concentration at Vmax / 2 |
| D. | Substrate concentration of twice Vmax |
| Answer» D. Substrate concentration of twice Vmax | |
| 46. |
True about genetic code except - |
| A. | Alpha rays |
| B. | Beta rays |
| C. | UV rays |
| D. | All of the above |
| Answer» B. Beta rays | |
| 47. |
In familial hypercholesterolemia there is deficiency of- |
| A. | Apo protein C |
| B. | Lipoprotein lipase |
| C. | LDL receptors |
| D. | Apo protein A |
| Answer» D. Apo protein A | |
| 48. |
Mlecular change in Lysosomal storage disorder - |
| A. | Increased sythesis of some substrates |
| B. | Defective fusion of lysosomes and phagosomes |
| C. | Membrane defect of lysosomes |
| D. | Mutation of genes encoding lysosomal hydrolase |
| Answer» E. | |
| 49. |
Which of the following elements is known to influence the body's ability to handle oxidative stress? |
| A. | Potassium |
| B. | Selenium |
| C. | Calcium |
| D. | Iron |
| Answer» C. Calcium | |
| 50. |
Gluconeogenesis in Fasting state is indicated by - |
| A. | Citrate activation by acetyl co-A carboxylase |
| B. | Pyruvate Carboxylase activation by acetyl coA |
| C. | Fructose 1,6 bisphosphate activates Pyruvate Kinase |
| D. | Fructose 2,6 bisphosphate activates PFK-1 |
| Answer» C. Fructose 1,6 bisphosphate activates Pyruvate Kinase | |