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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Urinary excretion of FIGLU is increased in deficiency of: |
| A. | Folic Acid |
| B. | Vit B12 |
| C. | Nicotinic acid |
| D. | Ascorbic acid |
| Answer» B. Vit B12 | |
| 2. |
Intron is not found in which DNA? |
| A. | Mitochondrial DNA |
| B. | Nuclear DNA |
| C. | Z DNA |
| D. | B DNA |
| Answer» B. Nuclear DNA | |
| 3. |
Lac operon transcription is induced by - |
| A. | Glucose |
| B. | Glucose with inducer |
| C. | Inducer without glucose |
| D. | All of the above |
| Answer» D. All of the above | |
| 4. |
Elongation arrest occurs due to - |
| A. | SRP |
| B. | SRP-R |
| C. | Docking protein |
| D. | Signal peptide |
| Answer» B. SRP-R | |
| 5. |
In gene cloning, largest fragment can be incorporated in - |
| A. | Plasmid |
| B. | Bacteriophage |
| C. | Cosmid |
| D. | Retrovirus |
| Answer» D. Retrovirus | |
| 6. |
NADPH actions in rbc are a/e - |
| A. | Produce ATP |
| B. | Stabilizes the membrane |
| C. | Reductive biosynthesis |
| D. | GP6D deficiency causes decreased synthesis of NADPH |
| Answer» B. Stabilizes the membrane | |
| 7. |
In which type of chromatography,the proteins are bound to another substance |
| A. | Hydrophobic chromatography |
| B. | Affinity chromatography |
| C. | Paper chromatography |
| D. | Gel chromatography |
| Answer» C. Paper chromatography | |
| 8. |
In a patient with starvation for 72 hrs which of the following would be seen - |
| A. | Degradation of proteins |
| B. | Increased gluconeogenesis |
| C. | Increased glycogenolysis |
| D. | Increased ketosis due to break down of fats |
| Answer» C. Increased glycogenolysis | |
| 9. |
Which of these amino acids will migrate slowest to the anode end at the physiological pH- |
| A. | Aspartic acid |
| B. | Glycine |
| C. | Lysine |
| D. | Valine |
| Answer» D. Valine | |
| 10. |
TCA cycle does not take place in - |
| A. | Neuron |
| B. | Erythrocyte |
| C. | Hepatocyte |
| D. | Osteocyte |
| Answer» C. Hepatocyte | |
| 11. |
False about folic acid - |
| A. | It is present in all the green leafy vegetables |
| B. | It is proven to decrease the occurrence of neural tube defects when taken preconceptionally |
| C. | Wheat flour in India is fortified with folate as in USA |
| D. | Methyl folate trap is because of methionine synthase defect |
| Answer» D. Methyl folate trap is because of methionine synthase defect | |
| 12. |
What is not given in fructose intolerance patient ? |
| A. | Glucose + Fructose |
| B. | Fructose + Galactose |
| C. | Fructose + Sucrose |
| D. | Fructose + Maltose |
| Answer» D. Fructose + Maltose | |
| 13. |
Eukaryotic plasma membrane us made up of all except |
| A. | Triglycerides |
| B. | Carbohydrates |
| C. | Cholesterol |
| D. | Lecithin |
| Answer» B. Carbohydrates | |
| 14. |
The Tertiary structure of protein is most commonly detected by |
| A. | X-ray crystallography |
| B. | Spectrophotometry |
| C. | Electrophoresis |
| D. | Chromatography |
| Answer» B. Spectrophotometry | |
| 15. |
Which of the following enzyme is inhibited by fluoride: |
| A. | Enolase |
| B. | Hexokinase |
| C. | Glucokinase |
| D. | Glucose-6- phophate |
| Answer» B. Hexokinase | |
| 16. |
Which coenzyme is responsible for carboxylation reaction? |
| A. | NADH |
| B. | Thiamine pyrophosphate |
| C. | Biotin |
| D. | FAD |
| Answer» D. FAD | |
| 17. |
Which of the following is not a rate limiting enzyme - |
| A. | Acetyl CoA carboxylase |
| B. | Malanote dehydrogenase |
| C. | HMG CoA reductase |
| D. | Phosphofructokinase |
| Answer» C. HMG CoA reductase | |
| 18. |
A person who is running the main source of energy he will using in 1st minute is ? |
| A. | Glycogen |
| B. | FFA |
| C. | Phosphagen |
| D. | Glucose |
| Answer» B. FFA | |
| 19. |
All are true about selenocystiene except - |
| A. | Considered 21st Amino acid |
| B. | Coded by UGA |
| C. | Occurs in glutathione peroxidase |
| D. | Made of cystine and methionine |
| Answer» E. | |
| 20. |
Acetyl CoA can be converted into all of the following,Except |
| A. | Cholesterol |
| B. | Ketone bodies |
| C. | Glucose |
| D. | Fatty Acids |
| Answer» D. Fatty Acids | |
| 21. |
Which one of the following pairs of lipids and related compounds exhibit opposite biological activities? |
| A. | 5-HPETE and leukotriene D4 |
| B. | Cholic acid and lithocholic acid |
| C. | Thromboxane A2 and prostocyclin (PGI2) |
| D. | Acetone and beta-hydroxybutyrate |
| Answer» D. Acetone and beta-hydroxybutyrate | |
| 22. |
Good cholesterol found in - |
| A. | VLDL |
| B. | IDL |
| C. | HDL |
| D. | LDL |
| Answer» D. LDL | |
| 23. |
Phosphofructokinase is the key enzyme of |
| A. | Glycolysis |
| B. | Gluconeogenesis |
| C. | Beta oxidation |
| D. | TCA cycle |
| Answer» B. Gluconeogenesis | |
| 24. |
Which amino acid can protonate and deprotonate at neutral pH - |
| A. | Glycine |
| B. | Arginine |
| C. | Histidine |
| D. | Leucine |
| Answer» D. Leucine | |
| 25. |
The 40 nm gap in between the tropocollagen molecule in collagen which serve as the site of bone formation is occupied by which of the following - |
| A. | Carbohydrate |
| B. | Ligand moiety |
| C. | Ca++ |
| D. | Fe+++ |
| Answer» D. Fe+++ | |
| 26. |
In a human genome project, scientist notice that one strand of the DNA molecule contains 20 thymine(T), 25 cytosine(C), 30 guanine(G), and 22 adenine(A) residues. How many of each of the base are found in the complete double-stranded molecule ? |
| A. | T=44, C=60, G=50, A= 40 |
| B. | T=22, C=30, G=25, A= 20 |
| C. | T=40, C=50, G=50, A= 44 |
| D. | T=42, C=55, G=55, A= 42 |
| Answer» E. | |
| 27. |
True regarding conversion of deoxyhemoglobin to oxyhemoglobin is - |
| A. | pH of blood has no affect on the binding of O2 |
| B. | Binding of O2 causes increased binding of 2,3, DPG |
| C. | Binding of O2 causes release of H+ |
| D. | One mole of deoxyhemoglobin binds with two moles of 2,3, DPG |
| Answer» D. One mole of deoxyhemoglobin binds with two moles of 2,3, DPG | |
| 28. |
The amino acid residue having an iminoside chain is: |
| A. | Tyrosine. |
| B. | Proline. |
| C. | Lysine. |
| D. | Histidine. |
| Answer» C. Lysine. | |
| 29. |
Which is smallest fundamental unit coding for DNA synthesis - |
| A. | Replican |
| B. | Anticodon |
| C. | Cistron |
| D. | Operon |
| Answer» D. Operon | |
| 30. |
Succinyl Co-A is formed by - |
| A. | Leucine |
| B. | Histidine |
| C. | Lysine |
| D. | Valine |
| Answer» E. | |
| 31. |
Creatinine is produced from: |
| A. | Aspartate |
| B. | Alanine |
| C. | Lysine |
| D. | Glycine |
| Answer» E. | |
| 32. |
Fructokinase is necessary for - |
| A. | Fructose 6 phosphate |
| B. | Glyceraldehyde |
| C. | Fructose 1-PO4 |
| D. | Ructose 1,6 diphosphate |
| Answer» D. Ructose 1,6 diphosphate | |
| 33. |
HDN is seen due to deficiency of vitamin - |
| A. | C |
| B. | A |
| C. | E |
| D. | K |
| Answer» E. | |
| 34. |
Which of the following does not contain carotene - |
| A. | Potato |
| B. | Tomato |
| C. | Carrot |
| D. | Spinach |
| Answer» B. Tomato | |
| 35. |
Cancer cells derive nutrition from |
| A. | Glycolysis |
| B. | Oxydative phosphorylation |
| C. | Increase in mitochondria |
| D. | From a fast food joint |
| Answer» B. Oxydative phosphorylation | |
| 36. |
Eukaryotic DNA polymerase involved in proof reading and DNA repair during replication is - |
| A. | alpha |
| B. | beta |
| C. | epsilon |
| D. | gamma |
| Answer» D. gamma | |
| 37. |
Post prandial utilization of glucose is by which enzyme ? |
| A. | Hexokinase |
| B. | Glucokinase |
| C. | Fructokinase |
| D. | All of the above |
| Answer» C. Fructokinase | |
| 38. |
Action of alpha-subunit of G protein is |
| A. | Internalization of receptors |
| B. | Binding of agonist |
| C. | Breakdown of GTP to GDP |
| D. | Conversion of GDP to GTP |
| Answer» D. Conversion of GDP to GTP | |
| 39. |
In the feed state, major fate of Glucose6-PO4 in tissue is - |
| A. | Enters HMP shunt via Ribulose 5-PO4 |
| B. | Storage as glycogen |
| C. | Storage as Fructose |
| D. | Storage as Glyceraldehyde 3-PO4 |
| Answer» C. Storage as Fructose | |
| 40. |
Which is the smallest fundamental unit coding for DNA synthesis: |
| A. | Operon |
| B. | Replican |
| C. | Cistron |
| D. | Anticodon |
| Answer» D. Anticodon | |
| 41. |
Major contribution towards gluconeogenesis is by - |
| A. | Ketones |
| B. | Alanine |
| C. | Lactate |
| D. | Glyeror |
| Answer» C. Lactate | |
| 42. |
What is meant by melting of double stranded by DNA - |
| A. | Formation of triple helix |
| B. | Separation of bases |
| C. | Splitting of double strands into single strand |
| D. | Splitting of DNA into fragments |
| Answer» D. Splitting of DNA into fragments | |
| 43. |
The cost in high-energy phosphate bonds for the formation of 1 mole of glucose from pyruvate is - |
| A. | 8 moles of ATP |
| B. | 6 moles of ATP |
| C. | 4 moles of ATP |
| D. | 2 moles of ATP |
| Answer» C. 4 moles of ATP | |
| 44. |
Following modification occurs in Gs submit which leads to watery diarrhea in cholera |
| A. | phosphorylation |
| B. | Dephosphorylation |
| C. | ADP ribosylation |
| D. | ATP-ADP transfer |
| Answer» D. ATP-ADP transfer | |
| 45. |
False about eukaryotic protein synthesis is |
| A. | Ef2 shifts between GDP to GTP |
| B. | Capping helps in attachment of mRNA to 40S ribosome |
| C. | N formyl Met is the first t-RNA to come into action |
| D. | mRNA read 5' to 3' |
| Answer» D. mRNA read 5' to 3' | |
| 46. |
Part of M-RNA removed during protein synthesis - |
| A. | Exon |
| B. | Suistron |
| C. | Interon |
| D. | Codon |
| Answer» D. Codon | |
| 47. |
Which is not pyridoxine dependent - |
| A. | Homocystinuria |
| B. | Male syrup urine disease |
| C. | Oxaluria |
| D. | Xanthinuria |
| Answer» C. Oxaluria | |
| 48. |
43s preinitiation complex include all except - |
| A. | IF2 beta |
| B. | IF-4F |
| C. | IF3 |
| D. | IF1A |
| Answer» C. IF3 | |
| 49. |
Aminoacid that enters the TCA cycle for gluconeogenesis and ketogenin in nature - |
| A. | Glycine |
| B. | Serine |
| C. | Pheylalanine |
| D. | Alanine |
| Answer» D. Alanine | |
| 50. |
Which of the following tests is not used for detection of specific aneuploidy |
| A. | QF-PCR |
| B. | Microarray |
| C. | FISH |
| D. | RT-PCR |
| Answer» C. FISH | |