MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The serine proteases do not include - |
| A. | Pepsin |
| B. | Trypsin |
| C. | Elastase |
| D. | Chymotrypsin |
| Answer» B. Trypsin | |
| 2. |
True about polymorphism is - |
| A. | Single locus - multiple abnormal alleles |
| B. | Single locus - multiple normal alleles |
| C. | Single phenotype : Single locus - multiple abnormal alleles |
| D. | Single phenotype : Single locus - multiple normal alleles |
| Answer» E. | |
| 3. |
Trans-amination of pyruvate and glutamic acid leads to the formation of |
| A. | Oxaloacetate |
| B. | Alpha-ketoglutarate |
| C. | Aspartate |
| D. | Malate |
| Answer» C. Aspartate | |
| 4. |
True statement regarding Nitric Oxide is: |
| A. | NO causes vasoconstriction |
| B. | NO is released from mytochondria |
| C. | NO is synthesized from arginine |
| D. | NO is spontaneou produced from NO2 |
| Answer» D. NO is spontaneou produced from NO2 | |
| 5. |
Glucose-6 Phosphate inhibits: |
| A. | Hexokinase |
| B. | Glucokinase |
| C. | Phosphofructokinase |
| D. | Pyruvate kinase |
| Answer» B. Glucokinase | |
| 6. |
All is true about fragment cleavage one degree structure determination except - |
| A. | Trypsin cleaves arginine next to proline |
| B. | Trypsin cleaves lysine residue(C) |
| C. | Performic acid break disulfide bond |
| D. | Trypsin and lysyl endoproteinase cleave C terminal of lysune |
| Answer» B. Trypsin cleaves lysine residue(C) | |
| 7. |
Pyrimidine metabolism features a/e - |
| A. | DHOA-dehydrogenase in mitochondrial |
| B. | Reye syndrome decrease cytosolic carbamoyl phosphate |
| C. | Require CAD polypeptide chain |
| D. | 6-azauridine l/t oritidinuria |
| Answer» C. Require CAD polypeptide chain | |
| 8. |
In muscle, phosphorylase b is inactivated by |
| A. | Glucose |
| B. | ATP |
| C. | cAMP |
| D. | Ca ions |
| Answer» C. cAMP | |
| 9. |
In which organelle of hepatocyte, the elongation of long chain fatty acid takes place - |
| A. | Mitochondria |
| B. | Golgi body |
| C. | Ribosome |
| D. | Lysosomes |
| Answer» B. Golgi body | |
| 10. |
All are involved in non toxic transport of ammonia except - |
| A. | Glutaminase |
| B. | Glutamine synthetase |
| C. | SGPT |
| D. | Alanine cycle |
| Answer» B. Glutamine synthetase | |
| 11. |
hn RNA seen in: |
| A. | Hutchinson chorea |
| B. | Alpha Thallasemia |
| C. | Spinal muscular dystrophy |
| D. | Sickle cell disease |
| Answer» D. Sickle cell disease | |
| 12. |
During gluconeogensis reducing equivalents from mitochondria to cytosol are transported by - |
| A. | Glutamate |
| B. | Oxaloacetate |
| C. | Malate |
| D. | Aspartate |
| Answer» D. Aspartate | |
| 13. |
Which of the following plant components is not fermented by gastrointestinal microorganisms |
| A. | Hemicellulose |
| B. | Pectin |
| C. | Lignin |
| D. | Cellulose |
| Answer» D. Cellulose | |
| 14. |
Km increased and Vmax same enzyme is - |
| A. | Irreversible |
| B. | Uncompetitive |
| C. | Competitive |
| D. | Non competitive |
| Answer» D. Non competitive | |
| 15. |
Correct pair of Ig subclass with their heavy chain - |
| A. | IgM - Delta |
| B. | IgE - Gamma |
| C. | IgM - Alpha |
| D. | IgG - Gamma |
| Answer» D. IgG - Gamma | |
| 16. |
The key regulatory enzyme in hepatic biosynthesis of heme is - |
| A. | Decarboxylase |
| B. | ALA synthesis |
| C. | Coproporphyrinogen oxidase |
| D. | Protoporphyrinogen oxidase |
| Answer» C. Coproporphyrinogen oxidase | |
| 17. |
Sequence which is responsible for retaining proteins in membrane - |
| A. | Sec 61 complex |
| B. | Translocon |
| C. | Docking protein |
| D. | Halt signal |
| Answer» E. | |
| 18. |
Which of the following is not required for protein synthesis in eukaryotes - |
| A. | RNA polymerase |
| B. | Ribosome |
| C. | Peptidyl transferase |
| D. | Amino acyl tRNA synthesis |
| Answer» B. Ribosome | |
| 19. |
Regarding Newtonian force,true is: |
| A. | Viscocity is equal to the velocity |
| B. | There is no relation between the two |
| C. | Viscocity is directly proportional to velocity |
| D. | Viscocity is inversly proportional to velocity |
| Answer» C. Viscocity is directly proportional to velocity | |
| 20. |
Vitamin A is present in all except - |
| A. | Sunflower seeds |
| B. | Egg |
| C. | Milk |
| D. | Tomato |
| Answer» B. Egg | |
| 21. |
Vitamin A intoxication causes injury to - |
| A. | Endoplasmic reticulum |
| B. | Microtubules |
| C. | Lysosomes |
| D. | Mitochondria |
| Answer» D. Mitochondria | |
| 22. |
All the following amino acid carry ammonia(NH3),participate in urea cycle except: |
| A. | Glycine |
| B. | Glutamate |
| C. | Aspartate |
| D. | Arginine |
| Answer» B. Glutamate | |
| 23. |
Sites where HMP shunt can occur include - |
| A. | Liver |
| B. | Lactating mammary gland |
| C. | Testes |
| D. | All of the above |
| Answer» E. | |
| 24. |
All of the following are true about Sickle cell disease,Except: |
| A. | RFLP results from a single base change |
| B. | Single nucleotide change results in change of Glutamine to Valine |
| C. | HbS confers resistance against malaria in heterozygotes |
| D. | Sticky patch' is generated as a result of replacement of a non polar residue with a polar residue |
| Answer» E. | |
| 25. |
The structural proteins are involved in maintaining the shape of a cell or in the formation of matrices in the body.The shape of these proteins is : |
| A. | Fibrous |
| B. | Globular |
| C. | Planar |
| D. | Stretch of beads |
| Answer» B. Globular | |
| 26. |
Weakest bond is - |
| A. | Covalent |
| B. | Hydrogen |
| C. | Electrolytic |
| D. | Vander wall |
| Answer» E. | |
| 27. |
Chargaff rule state that- |
| A. | A = U = T = G = C |
| B. | A + G = T + C |
| C. | A + T = G + C |
| D. | A/T = G/C |
| Answer» E. | |
| 28. |
Hydrolysis occurs at which step of urea cycle ? |
| A. | Cleavage of Arginine |
| B. | Formation of Argininosuccinate |
| C. | Formation of Citrulline |
| D. | Formation of ornithine |
| Answer» B. Formation of Argininosuccinate | |
| 29. |
Nucleoside is made up of - |
| A. | Pyrimidine |
| B. | Purine |
| C. | Sugar |
| D. | All of the above |
| Answer» E. | |
| 30. |
Reasons for ketone body synthesis in Von Gierkes Disease except - |
| A. | Hypoglycemia |
| B. | Oxaloacetate is necessary for gluconeognesis |
| C. | Low blood glucose less than 40 mg% |
| D. | Fatty acid mobilization is low |
| Answer» E. | |
| 31. |
Cation used in PCR is - |
| A. | Lithium |
| B. | Calcium |
| C. | Sodium |
| D. | Magnesium |
| Answer» E. | |
| 32. |
Coenzyme, in an enzymatic reaction usually functions to - |
| A. | Enhance the specificity of apoenzyme |
| B. | Accept one of the cleavage products |
| C. | Activate the substrate |
| D. | Increase the active sites of apoenzyme |
| Answer» C. Activate the substrate | |
| 33. |
SYBR Green Dye is used for - |
| A. | Immunoflurescence |
| B. | HPLC |
| C. | ELISA |
| D. | PCR |
| Answer» E. | |
| 34. |
Ribonuclease-P is ? |
| A. | Ligase |
| B. | Lyase |
| C. | Ribozyme |
| D. | Hydrolase |
| Answer» D. Hydrolase | |
| 35. |
Total number of genes in a human begin is - |
| A. | 100000 |
| B. | 30000 |
| C. | 800000 |
| D. | 50000 |
| Answer» C. 800000 | |
| 36. |
Cytochrome oxidase in oxidative phosphorylation is inhibited by - |
| A. | CO |
| B. | H2S |
| C. | Cyanide |
| D. | All of the above |
| Answer» E. | |
| 37. |
Bromodeoxyuridine is related to DNA in |
| A. | Uracil |
| B. | Adenosine |
| C. | Cytosine |
| D. | Thymidine |
| Answer» E. | |
| 38. |
All of the following are true regarding oxygenases except: |
| A. | Incorporate 2 atoms of oxygen |
| B. | Incorporate 1 atom of oxygen |
| C. | Required for hydroxylation of steriods |
| D. | Required for carboxylation of drugs. |
| Answer» E. | |
| 39. |
Y-chromosome is - |
| A. | Sub-metacentric |
| B. | Metacentric |
| C. | Longer than the X-chromosome |
| D. | Acrocentric |
| Answer» E. | |
| 40. |
In Eukaryotes,the number of polypeptides synthesized from one m-RNA is: |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 5 |
| Answer» B. 2 | |
| 41. |
About t-RNA, true is - |
| A. | No intrabasal pairing |
| B. | Clover leaf pattern |
| C. | Inverted T appearance |
| D. | Each specific for m-RNA |
| Answer» C. Inverted T appearance | |
| 42. |
Which of these is NOT an essential amino acid ? |
| A. | Histidine |
| B. | Homocysteine |
| C. | Lysine |
| D. | Valine |
| Answer» C. Lysine | |
| 43. |
In Metabolic alkalosis, which is true about excretion in urine - |
| A. | Betahydroxy butyric acid |
| B. | Less ammonia |
| C. | More of NH3 |
| D. | Less of aceto acetic acid |
| Answer» C. More of NH3 | |
| 44. |
Acetyl Co-A acts as a substrate for all the enzymes except: |
| A. | HMG-Co A synthetase |
| B. | Malic enzyme |
| C. | Malonyl Co A synthetase |
| D. | Fatty acid synthetase |
| Answer» C. Malonyl Co A synthetase | |
| 45. |
Hemoglobin estimation is done by all except - |
| A. | Wintrobes |
| B. | Drabkin's |
| C. | Spectrophotometry |
| D. | Sahli's |
| Answer» B. Drabkin's | |
| 46. |
Following required for normal growth - |
| A. | Protooncogenes |
| B. | Tumour suppressor genes |
| C. | DNA repair genes |
| D. | All of the above |
| Answer» E. | |
| 47. |
Basement membrane degeneration is mediated by: |
| A. | Metalloproteinases |
| B. | Oxidases |
| C. | Elastases |
| D. | Hydroxylases |
| Answer» B. Oxidases | |
| 48. |
The most common enzyme deficiency in man is - |
| A. | Glucose-6-phosphate |
| B. | Glucose-1.6-phosphate |
| C. | Glucose-6-phosphate dehydrogenase |
| D. | Hexokinase |
| Answer» D. Hexokinase | |
| 49. |
True about isoenzymes is/are - |
| A. | Different km value |
| B. | Consists of multimeric complex |
| C. | Have different physical properties |
| D. | All of the above |
| Answer» E. | |
| 50. |
For measurement of long DNA molecules(50-100KB) following is used - |
| A. | Nitch |
| B. | Chromosome walking |
| C. | SSLP |
| D. | RFLP |
| Answer» E. | |