MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
One of the following enzyme is not a protein: |
| A. | DNAase |
| B. | Abzyme |
| C. | EcoRI |
| D. | Ribozyme |
| Answer» E. | |
| 2. |
Liver enzyme dephosphorylation to phosphorylation true is- |
| A. | More commonly seen in fasting state than in fed state |
| B. | Always activated by cAMP dependent Protein kinase |
| C. | Always activates the enzyme |
| D. | Catecholamines stimulate it |
| Answer» C. Always activates the enzyme | |
| 3. |
Which DNA polymerase is/are involved in repair of mammalian DNA - |
| A. | Beta |
| B. | Alpha |
| C. | Both A and B |
| D. | None |
| Answer» B. Alpha | |
| 4. |
All of the following statements about LDL are true except - |
| A. | It is a marker for cardiovascular disease |
| B. | It contains Apo-B4 |
| C. | It delivers cholesterol to cells |
| D. | It contains only one Apoprotein |
| Answer» C. It delivers cholesterol to cells | |
| 5. |
Pyruvate can be converted directly into all of the following except: |
| A. | Acetyl CoA |
| B. | Lactate |
| C. | Phosphoenol pyruvate |
| D. | Alanine |
| Answer» D. Alanine | |
| 6. |
In noncompetitive antagonism the true statement is - |
| A. | Km value decreased; V max decreased |
| B. | Km value decreased; V max normal |
| C. | Km value decreased; V max increased |
| D. | Km value normal; V max decreased |
| Answer» E. | |
| 7. |
Which of the following is a functional enzyme ? |
| A. | LDH |
| B. | Amylase |
| C. | Prothrombin |
| D. | Acid phosphatase |
| Answer» D. Acid phosphatase | |
| 8. |
Which of the following is a derived lipid ? |
| A. | Triacylglycerol |
| B. | b-hydroxybutyrate |
| C. | Sphingomyelin |
| D. | Phosphatidyl serine |
| Answer» C. Sphingomyelin | |
| 9. |
Microsatellite sequence is: |
| A. | Extra chromosomal DNA |
| B. | Small satellite |
| C. | Looped-DNA |
| D. | Short sequence (2-5) repeat DNA |
| Answer» E. | |
| 10. |
Ferric chloride test is PKU gives - |
| A. | Green |
| B. | Red |
| C. | Yellow |
| D. | Blue |
| Answer» B. Red | |
| 11. |
Triglycerides are maximum in - |
| A. | LDL |
| B. | HDL |
| C. | Chylomicrons |
| D. | VLDL |
| Answer» D. VLDL | |
| 12. |
Enzyme involved in Von Grike disease is ? |
| A. | Muscle glycogen phosphorylase |
| B. | Glucose 6 Phosphatase |
| C. | Debranching enzyme |
| D. | Branching enzyme |
| Answer» C. Debranching enzyme | |
| 13. |
Which vitamin is required for carboxylation of clotting factors? |
| A. | Vitamin E |
| B. | Vitamin K |
| C. | Vitamin A |
| D. | Vitamin D |
| Answer» C. Vitamin A | |
| 14. |
In glutathione which amino acid is reducing agent - |
| A. | Glycine |
| B. | Glutamic acid |
| C. | Alanine |
| D. | Cysteine |
| Answer» E. | |
| 15. |
Steroid receptor regulatory protein - |
| A. | Leucine zippor |
| B. | RNA |
| C. | Zinc finger |
| D. | Heliz -turn - helix |
| Answer» D. Heliz -turn - helix | |
| 16. |
Vitamin which is excreted in urine is - |
| A. | Vitamin C |
| B. | Vitamin A |
| C. | Vitamin K |
| D. | Vitamin D |
| Answer» B. Vitamin A | |
| 17. |
Defect in folding of the protein result in which of the following clinical disease: |
| A. | Kuru |
| B. | Migraine |
| C. | Hypothyroidism |
| D. | Myopia |
| Answer» B. Migraine | |
| 18. |
Definition of Ribozyme - |
| A. | m-RNA |
| B. | Ribosome |
| C. | RNA molecular that acts catalytically to change it self or another RNA molecular |
| D. | t-RNA |
| Answer» D. t-RNA | |
| 19. |
Which of the following enzymes are associated with break down H2O2 - |
| A. | Oxygenase |
| B. | Hydrolase |
| C. | Catalase |
| D. | Oxidase |
| Answer» D. Oxidase | |
| 20. |
Enzymes fond in CSF |
| A. | ALP + CK - MB |
| B. | GGT + ALP |
| C. | Deaminase and Peroxidase |
| D. | CK + LDH |
| Answer» E. | |
| 21. |
Which of these amino acids does not have anomeric carbon atom: |
| A. | Valine |
| B. | Alanine |
| C. | Tyrosine |
| D. | Glycine |
| Answer» E. | |
| 22. |
Activator of enzyme sulfite oxidase is ? |
| A. | Copper |
| B. | Zinc |
| C. | Molybdenum |
| D. | Iron |
| Answer» D. Iron | |
| 23. |
1st product of tryptophan catabolism is ? |
| A. | Kynerunine |
| B. | Bradykinin |
| C. | PAF |
| D. | Xantheurenate |
| Answer» B. Bradykinin | |
| 24. |
Which of the following is a denaturing substance? |
| A. | Guanosine |
| B. | Guanidine |
| C. | Glutamate |
| D. | Glycine |
| Answer» C. Glutamate | |
| 25. |
'All enzymes are not proteins'.This statement is justified by: |
| A. | RNAs act as ribozymes |
| B. | All enzymes do not follow the Michaelis Menton hypothesis |
| C. | Metals are involved in attachment to enzymes and catalysis |
| D. | Antibodies take part in the catalysis of many reactions |
| Answer» B. All enzymes do not follow the Michaelis Menton hypothesis | |
| 26. |
Fluoride inhibits which enzyme - |
| A. | Aldolase |
| B. | Succinate hydrogenase |
| C. | Pyruvate kinase |
| D. | Enolase |
| Answer» E. | |
| 27. |
In the body, metabolism of 10 grams of protein would produce approximately - |
| A. | 1 K calorie |
| B. | 41 K calories |
| C. | 410 K calories |
| D. | 41 calories |
| Answer» C. 410 K calories | |
| 28. |
POlyamine like putrescine is derived from ? |
| A. | Arginine |
| B. | Ornithine |
| C. | Yohimibine |
| D. | Arginosuccine |
| Answer» C. Yohimibine | |
| 29. |
True about PCR - |
| A. | Primers required |
| B. | DNA depend RNA polymerase |
| C. | RNA depend DNA polymerase |
| D. | All of the above |
| Answer» B. DNA depend RNA polymerase | |
| 30. |
The pathway that can produce energy even in the absence of O2 is - |
| A. | TCA cycle |
| B. | Glycolysis |
| C. | Fatty acid oxidation |
| D. | Respiratory chain |
| Answer» C. Fatty acid oxidation | |
| 31. |
Compounds that joints glycolysis with glycogenesis and glycogenolysis - |
| A. | Glucose 1 PO4 |
| B. | Glucose 1,6-bi phosphate |
| C. | Fructose 1, 6-bi phosphate |
| D. | Glucose 6 PO4 |
| Answer» E. | |
| 32. |
Gene transmitted but not translated - |
| A. | t-RNA |
| B. | Glycosyl transferase |
| C. | Histone |
| D. | Keratin |
| Answer» B. Glycosyl transferase | |
| 33. |
A child presents with hepatomegaly and bilateral lenticular opacities. Deficiency of which of the following enzymes will not cause such features - |
| A. | Galactosekinase |
| B. | Lactase |
| C. | Galactose -1 phosphate uridyl transferase |
| D. | UDP Galactose -4- epimerase |
| Answer» C. Galactose -1 phosphate uridyl transferase | |
| 34. |
All of the following are associated with increased risk of atherosclerotic plaque formation except: |
| A. | Increased homocysteine |
| B. | Increased Alpha 2 macroglobulin |
| C. | Apo E mutation |
| D. | Oxidized LDL |
| Answer» C. Apo E mutation | |
| 35. |
In Phenyliketonuria the main main of first line therapy is: |
| A. | Replacement of the defictive product |
| B. | Replcement of the defictive enzyme |
| C. | Giving the missing amino acid by diet |
| D. | Limiting the substrate for defictive enzyme |
| Answer» E. | |
| 36. |
Phosphorylase b is maintained in an inactivated state by |
| A. | Calcium |
| B. | Insulin |
| C. | ATP |
| D. | c AMP |
| Answer» C. ATP | |
| 37. |
In SDS-PAGE(sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis) proteins are separated on basis of - |
| A. | Density |
| B. | Solubility |
| C. | Mass |
| D. | Charge |
| Answer» D. Charge | |
| 38. |
The gaps between segments of DNA on the lagging strand produced by restriction enzymes are rejoined/sealed by |
| A. | DNA topoisomerase |
| B. | DNA phosphorylase |
| C. | DNA Ligases |
| D. | DNA Helicase |
| Answer» D. DNA Helicase | |
| 39. |
True regarding Glycogenolysis is/are A/E - |
| A. | Vasopressin increases it |
| B. | PP1 is a dephosphorylating enzyme |
| C. | Ca++is a synchronizer and allosteric activator |
| D. | Oxytocin decrease it |
| Answer» E. | |
| 40. |
Catabolism of H2O2 is carried out by |
| A. | Peroxisomes |
| B. | Mitochondria |
| C. | Endoplasmic reticulum |
| D. | Lysosomes |
| Answer» B. Mitochondria | |
| 41. |
Which of the following enzymes is a constituent of HMP shunt - |
| A. | Hexokinase |
| B. | Glucose 6 phosphate |
| C. | Phosphorylase |
| D. | G-6-P dehydrogenase |
| Answer» E. | |
| 42. |
Ribozymes is/are - |
| A. | Recognition of codons in introns |
| B. | RNA polymerase |
| C. | Splicing of polypeptide chain and mRNA |
| D. | Transcription of mRNA |
| Answer» C. Splicing of polypeptide chain and mRNA | |
| 43. |
Enzymes that move a molecular group from one molecule to another are known as: |
| A. | Oxido-reductases. |
| B. | Ligases. |
| C. | Dipeptidases. |
| D. | Transferases. |
| Answer» E. | |
| 44. |
Mitochondrial DNA is: |
| A. | Linear |
| B. | Open circular |
| C. | Closed circular |
| D. | Nicked circular |
| Answer» D. Nicked circular | |
| 45. |
Which of the glucose transport receptor is associated with glucose absorption in small intestine: |
| A. | GLUT 2 |
| B. | GLUT 3 |
| C. | GLUT 4 |
| D. | GLUT 5 |
| Answer» B. GLUT 3 | |
| 46. |
End product of purine metabolism is ? |
| A. | Alamine |
| B. | Uric acid |
| C. | Ammonia |
| D. | Allantoin |
| Answer» C. Ammonia | |
| 47. |
Steroid receptor superfamily is present in - |
| A. | Vitamin D3 |
| B. | Insulin |
| C. | Glucagon |
| D. | Thyroid |
| Answer» B. Insulin | |
| 48. |
Secretory proteins are synthesized in - |
| A. | Cytoplasm |
| B. | Endoplasmic reticulum |
| C. | First in cytoplasm and then in endoplasmic reticulum |
| D. | First in endoplasmic reticulum and then in cytoplasm |
| Answer» C. First in cytoplasm and then in endoplasmic reticulum | |
| 49. |
All are processing reactions in tRNA except - |
| A. | Poly(A) tailing |
| B. | CCA tailing |
| C. | Trimming of 5' end |
| D. | Methylation of bases |
| Answer» B. CCA tailing | |
| 50. |
Endogenous triglycerides in plasma are maximally carried in: |
| A. | LDL |
| B. | HDL |
| C. | VLDL |
| D. | Chylomicrons |
| Answer» D. Chylomicrons | |