MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Scurvy is caused by deficiency of |
| A. | Vitamin D |
| B. | Vitamin C |
| C. | Vitamin E |
| D. | Vitamin B complex |
| Answer» C. Vitamin E | |
| 2. |
Gluconeogenesis does not occur sighnificantly from ....in humans - |
| A. | Fatty acids |
| B. | Lactate |
| C. | Amino acid |
| D. | Pyruvate |
| Answer» B. Lactate | |
| 3. |
All taken place in mitochondria except - |
| A. | EMP pathway |
| B. | Fatty acid oxidation |
| C. | Citric acid cycle |
| D. | Electron transport chain |
| Answer» B. Fatty acid oxidation | |
| 4. |
In G-6PD deficient patient haemolysis is due to decrease in - |
| A. | H+ |
| B. | TPP |
| C. | NADH |
| D. | NADPH |
| Answer» E. | |
| 5. |
Lactose produced by glycolysis is used by ? |
| A. | Gluconeogenesis and Glycolysis |
| B. | Cori cyle and TCA cycle |
| C. | TCA cycle and Glycogenolysis |
| D. | Cori cycle only |
| Answer» C. TCA cycle and Glycogenolysis | |
| 6. |
True about RIBOZYME |
| A. | Portiapate in DNA synthesis |
| B. | GTPase |
| C. | Pepitdyl transfuse activity |
| D. | Cut DNA at specific site |
| Answer» D. Cut DNA at specific site | |
| 7. |
No loss of genetic material occurs in |
| A. | Substitution |
| B. | Inversion |
| C. | Deletion |
| D. | Insertion |
| Answer» C. Deletion | |
| 8. |
Gluconeogenesis can occur from all except - |
| A. | Aceto acetate |
| B. | Lactic acid |
| C. | Alanine |
| D. | Glycerol |
| Answer» B. Lactic acid | |
| 9. |
Muscle can not make use of glycogen for energy because of deficiency of - |
| A. | Phosphoglucomutase |
| B. | Glucokinase |
| C. | Muscle phosphorylase |
| D. | G-6 phosphatase |
| Answer» E. | |
| 10. |
Restriction endonuclease is: |
| A. | Break double stranded DNA |
| B. | Break single stranded DNA |
| C. | Break RNA |
| D. | Break peptide chain |
| Answer» B. Break single stranded DNA | |
| 11. |
Cholesterol presents in LDL - |
| A. | Binds to a receptor and diffuses across the cell membrance |
| B. | Represent primarily cholesterol that is being removed from peripheral cells . |
| C. | When enters a cell, suppresses activity of acyl CoA : cholesterol acytransfearse ACAT |
| D. | On accumulation in the cell inhibits replenishment of LDL receptors |
| Answer» E. | |
| 12. |
Different sequence of amino acids having similar structure of proteins is an example of - |
| A. | Convergence |
| B. | Divergence |
| C. | Incidental |
| D. | Opportunistic |
| Answer» B. Divergence | |
| 13. |
Correct sequence of enzymes required for DNA formation is - |
| A. | Protein unwinding enzyme - Polymerase 1 - DNA ligase - DNA Isomerase - DNA polymerase |
| B. | DNA polymerase - protein unwinding enzyme - DNA ligase - DNA Isomerase - Polymerase 1 |
| C. | RNA polymerase - DNA polymerase III - DNA ligase - Exonuclease - DNA polymerase I |
| D. | RNA polymerase - DNA polymerase III - DNA polymerase I - DNA ligase |
| Answer» E. | |
| 14. |
Source of ammonia in urine - |
| A. | Glutamate dehydrogenase |
| B. | Arginase |
| C. | Glutaminase |
| D. | Urease |
| Answer» D. Urease | |
| 15. |
Introns are exised by - |
| A. | DNAase |
| B. | Helicase |
| C. | RNA splicing |
| D. | RNA editing |
| Answer» D. RNA editing | |
| 16. |
Which of the following require template for it's formation - |
| A. | Carbohydrate |
| B. | Protein |
| C. | Lipid |
| D. | All of the above |
| Answer» C. Lipid | |
| 17. |
Anticoagulant used to estimate glucose from a sample sent from PHC ic - |
| A. | EDTA |
| B. | Calcium oxalate |
| C. | Potassium oxalate + NaF |
| D. | Sodium citrate |
| Answer» D. Sodium citrate | |
| 18. |
Malonate competetively inhibits - |
| A. | Fumarate dehydrogenase |
| B. | Succinate thiokinase |
| C. | Aconitase |
| D. | Succinate dehydrogenase |
| Answer» E. | |
| 19. |
Acetyl CoA aids in fatty acid synthesis due to: |
| A. | Citrate lyase |
| B. | Thiolase |
| C. | Citrate decarboxylase |
| D. | Aldolase |
| Answer» B. Thiolase | |
| 20. |
Dietery cholesterol is delivered transported to extra hepatic tissue by: |
| A. | LDL |
| B. | VLDL |
| C. | IDL |
| D. | Chylomicrons |
| Answer» B. VLDL | |
| 21. |
A middle aged woman on oral contraceptives for many years,developed neurological symptoms such as depression,irritability,nervousness and mental confusion.Her hemoglobin level was 8g/dl.Biochemical investigations revealed that she was excreting highly elevated concentrations of xanthurenic acid in urine.She also showed high levels of triglycerides and cholesterol in serum.All of the above findings are most probably related to vitamin B6 deficiency caused by prolonged oral contraceptive use except: |
| A. | Decreased hemoglobin level |
| B. | Increased triglyceride and cholesterol level |
| C. | Increased urinary xanthurenic acid excretion |
| D. | Neurological symptoms by decreased synthesis of biogenic amines |
| Answer» C. Increased urinary xanthurenic acid excretion | |
| 22. |
The enzyme deficient in Von-Gierke's disease is |
| A. | Glucokinase |
| B. | Glucose 6 phosphatase |
| C. | Phospho Fructokinase |
| D. | Glycogen Synthase |
| Answer» C. Phospho Fructokinase | |
| 23. |
For measurement of long DNA molecules (50-100KB) following is used - |
| A. | Nitch |
| B. | Chromosome walking |
| C. | RFLP |
| D. | SSLP |
| Answer» D. SSLP | |
| 24. |
In Gaucher's disease, there is deficiency of - |
| A. | Glucocerebrosidase |
| B. | Glucokinase |
| C. | Sphingomyelinase |
| D. | G-6PD |
| Answer» B. Glucokinase | |
| 25. |
Km of an enzyme is: |
| A. | The normal physiological substrate concentration |
| B. | The substrate concentration at half maximum velocity |
| C. | Dissociation constant |
| D. | Numerically identical for all isozymes that catalyze a given reaction |
| Answer» C. Dissociation constant | |
| 26. |
Familial hypercholesterolemia is |
| A. | Deficient HDL receptors |
| B. | Deficient LDL receptors |
| C. | Deficient VLDL receptors |
| D. | HMG CoA reductase deficiency |
| Answer» C. Deficient VLDL receptors | |
| 27. |
In DNA the coding region reads 5'-CGT-3'. This would code in the RNA as - |
| A. | 5'-ACG-3' |
| B. | 5'-UGC-3' |
| C. | 5'-CGU-3' |
| D. | 5'-GCA-3' |
| Answer» D. 5'-GCA-3' | |
| 28. |
In sickle cell anemia, the defect can be explained as having arisen from - |
| A. | A base insertion in DNA |
| B. | A base deletion in DNA |
| C. | A base substitution in DNA |
| D. | All of the above |
| Answer» D. All of the above | |
| 29. |
Which of the following does not cross the cell membrane - |
| A. | Nitrous oxide |
| B. | Carbon monoxide |
| C. | Glucose 6-phosphate |
| D. | Glucose |
| Answer» D. Glucose | |
| 30. |
Glucose transport in myocyte stimulated by insulin is - |
| A. | GLUT 3 |
| B. | GLUT 4 |
| C. | GLUT 1 |
| D. | GLUT 2 |
| Answer» C. GLUT 1 | |
| 31. |
The cause of hyperuricemia and gout in glucose-6 phosphatase deficiency is - |
| A. | Increased accumulation of sorbitol |
| B. | Impaired degradation of free radicals |
| C. | More formation of pentose |
| D. | Decreased availability of glucose to tissues |
| Answer» D. Decreased availability of glucose to tissues | |
| 32. |
Hyperammonaemia inhibit TCA cycle by depleting - |
| A. | Alpha-ketoglutrate |
| B. | Oxaloacetate |
| C. | Fumarate |
| D. | Citrate |
| Answer» B. Oxaloacetate | |
| 33. |
On complete hydrolysis of DNA,we will get all of the following except |
| A. | Adenosine |
| B. | Purine base |
| C. | Phosphoric acid |
| D. | Dexose pentose sugar |
| Answer» B. Purine base | |
| 34. |
Least post translation modification occurs in - |
| A. | Eukaryotic r-RNA |
| B. | Prokaryotic m-RNA |
| C. | t-RNA |
| D. | Prokaryotic r-RNA |
| Answer» C. t-RNA | |
| 35. |
Nitrogen to caloric ratio is total parentral nutrition is |
| A. | 1 gm of N2 : 150 non protein calories |
| B. | 1 gm of N2 : 100 non protein calories |
| C. | 1.25 gm of N2 : 100 non protein calories |
| D. | 1.25 gm of N2 : 150 non protein calories |
| Answer» B. 1 gm of N2 : 100 non protein calories | |
| 36. |
In collagen synthesis,hydroxylation of Proline to Hydroxyproline requires all except |
| A. | Pyridoxal phosphate |
| B. | Vitamin C |
| C. | Oxygen |
| D. | Di-oxygenase |
| Answer» B. Vitamin C | |
| 37. |
Apoprotein A is found in: |
| A. | VLDL |
| B. | Chylomicrons |
| C. | LDL |
| D. | HDL |
| Answer» E. | |
| 38. |
Metabolism of tryptophan can give rise to - |
| A. | Diarrhoea |
| B. | Vasoconstriction |
| C. | Flushing |
| D. | All of the above |
| Answer» E. | |
| 39. |
Active sites of serine protease contain - |
| A. | Arginine |
| B. | Serine |
| C. | Histidine |
| D. | Lysine or threonine |
| Answer» C. Histidine | |
| 40. |
Folding of protein chain is due to - |
| A. | Hydrogen bonds |
| B. | Amide bond |
| C. | Disulphide bond |
| D. | Phosphodiesterase bonds |
| Answer» B. Amide bond | |
| 41. |
A buffer that is most effective at a pH of about 4.5 is; |
| A. | Acetate buffer |
| B. | Bicarbonate buffer |
| C. | Phosphate buffer |
| D. | Tris buffer |
| Answer» B. Bicarbonate buffer | |
| 42. |
DNA supercoiling is done by - |
| A. | DNA polymerase I |
| B. | DNA polymerase II |
| C. | DNA topoisomerase |
| D. | DNA gyrase |
| Answer» E. | |
| 43. |
Most stable amino acid at the physiological pH is - |
| A. | Arginine |
| B. | Glycine |
| C. | Histidine |
| D. | Lysine |
| Answer» D. Lysine | |
| 44. |
DNA estimation can done by - |
| A. | Spirometer |
| B. | Spectrophotometer |
| C. | pH meter |
| D. | Sphygmometer |
| Answer» E. | |
| 45. |
Which of the following events does not occur when concentration of glucose in the liver decreases: |
| A. | Activation of Fructose Bisphosphatase-2(Fructose 2,6 Bisphosphatase) |
| B. | Inactivation of phosphofructokinase-2(PFK-2) |
| C. | Increased levels of Glucagon |
| D. | Increased levels of Fructose 2 ,6-Bisphosphate |
| Answer» E. | |
| 46. |
Tangiers disease is characterized by - |
| A. | Low or absence of HDL |
| B. | Deficiency of LPL |
| C. | Low LDL concentration |
| D. | Raised chylomicrons |
| Answer» B. Deficiency of LPL | |
| 47. |
In which type of chromatography, the proteins are bound to another substance - |
| A. | Affinity chromatography |
| B. | Hydrophobic chromatography |
| C. | Gel chromatography |
| D. | Paper chromatography |
| Answer» B. Hydrophobic chromatography | |
| 48. |
Which of these amino acids does not have anomeric carbon atom - |
| A. | Tyrosine |
| B. | Glycine |
| C. | Valine |
| D. | Alanine |
| Answer» C. Valine | |
| 49. |
Splicing Activity is a function of: |
| A. | sn RNA |
| B. | mRNA |
| C. | t RNA |
| D. | r RNA |
| Answer» B. mRNA | |
| 50. |
Glycogen storage diseases include all of the following except - |
| A. | Fabry's disease |
| B. | Fragile syndrome |
| C. | Krabbe's disease |
| D. | All of the above |
| Answer» E. | |