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This section includes 26 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
One of the fundamental events that occur in meiosis is crossing over in which homologous chromosomes exchange segments causing a reshuffling of genes. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
In medical applications, the ultimate goal of gene mapping is to disease genes. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
Cytologic maps can be considered to be of _____ resolution and hence somewhat ______ physical maps. |
| A. | very high, inaccurate |
| B. | very low, accurate |
| C. | very high, accurate |
| D. | very low, inaccurate |
| Answer» E. | |
| 4. |
One centiMorgan is defined as _________ percentage of the total recombination events. |
| A. | one |
| B. | ten |
| C. | 0.1 |
| D. | 0.01 |
| Answer» B. ten | |
| 5. |
Name the mapping technique used to determine the position of restriction sites in a DNA molecule. |
| A. | Genetic map |
| B. | Restriction mapping |
| C. | Biochemical markers |
| D. | DNA markers |
| Answer» C. Biochemical markers | |
| 6. |
Out of the following, which technique detect single nucleotide polymorphism? |
| A. | RFLP |
| B. | AFLP |
| C. | SSLP |
| D. | SNP |
| Answer» E. | |
| 7. |
The map of the chromosome which shows identifiable sites is called___________ |
| A. | Gene expression |
| B. | Genome sequencing |
| C. | Chromosome walking |
| D. | Genome map |
| Answer» E. | |
| 8. |
OUT_OF_THE_FOLLOWING,_WHICH_TECHNIQUE_DETECT_SINGLE_NUCLEOTIDE_POLYMORPHISM??$ |
| A. | RFLP |
| B. | AFLP |
| C. | SSLP |
| D. | SNP |
| Answer» E. | |
| 9. |
IN_MEDICAL_APPLICATIONS,_THE_ULTIMATE_GOAL_OF_GENE_MAPPING_IS_TO_DISEASE_GENES.?$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 10. |
Name_the_mapping_technique_used_to_determine_the_position_of_restriction_sites_in_a_DNA_molecule.$ |
| A. | Genetic map |
| B. | Restriction mapping |
| C. | Biochemical markers |
| D. | DNA markers |
| Answer» C. Biochemical markers | |
| 11. |
One_of_the_fundamental_events_that_occur_in_meiosis_is_crossing_over_in_which_homologous_chromosomes_exchange_segments_causing_a_reshuffling_of_genes.$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 12. |
Which of the following technique is used for the amplification of DNA fragments? |
| A. | AFLP |
| B. | RFLP |
| C. | RAPD |
| D. | SSLP |
| Answer» D. SSLP | |
| 13. |
Cytologic maps can be considered to be of _____ resolution and hence somewhat ______ physical maps? |
| A. | very high, inaccurate |
| B. | very low, accurate |
| C. | very high, accurate |
| D. | very low, inaccurate |
| Answer» E. | |
| 14. |
What is the full form of RFLP? |
| A. | Restriction Fragment Length Polymorphisms |
| B. | Random Fragment Length Polymorphism |
| C. | Restriction Find in Length of DNA Polymer |
| D. | Restriction Fragment Length Polymers |
| Answer» B. Random Fragment Length Polymorphism | |
| 15. |
Which of the following is untrue about cytologic maps? |
| A. | They cannot be directly observed under microscope |
| B. | They refer to banding patterns |
| C. | They can be viewed on stained chromosomes |
| D. | They can be directly observed under microscope |
| Answer» B. They refer to banding patterns | |
| 16. |
Which of the following is NOT a DNA marker? |
| A. | RAPD |
| B. | Hormone |
| C. | RFLP |
| D. | AFLP |
| Answer» C. RFLP | |
| 17. |
Physical maps are constructed by using a chromosome walking technique. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 18. |
Which of the following statement is NOT true for genetic markers? |
| A. | A gene or a DNA sequence |
| B. | Associated with a particular trait |
| C. | Anything can be used as a genetic marker |
| D. | The first genetic map was prepared was of fruit fly |
| Answer» D. The first genetic map was prepared was of fruit fly | |
| 19. |
Physical maps are maps of locations of identifiable landmarks on a genomic DNA _______ inheritance patterns. |
| A. | remotely related to |
| B. | related to |
| C. | regardless of |
| D. | associated with |
| Answer» D. associated with | |
| 20. |
What is the unit of a genetic map? |
| A. | Centimeter |
| B. | Nanometer |
| C. | Angstrom |
| D. | Centimorgan |
| Answer» E. | |
| 21. |
One centiMorgan is defined as ____ percentage of the total recombination events. |
| A. | one |
| B. | ten |
| C. | 0.1 |
| D. | 0.01 |
| Answer» B. ten | |
| 22. |
What is chromosome walking? |
| A. | Hybridization technique |
| B. | Sequencing technique |
| C. | Genetic marker |
| D. | Chemical degradation technique |
| Answer» B. Sequencing technique | |
| 23. |
Genetic linkage maps, also called genetic maps, identify the relative positions of genetic markers on a chromosome and are based on how frequent the markers are inherited together. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 24. |
Location of genetic markers is facilitated by physical mapping on the basis of the frequency of recombination. |
| A. | True |
| B. | False |
| Answer» C. | |
| 25. |
Genetic markers are ______ portions of a _______ whose inheritance patterns can be followed. |
| A. | unidentifiable, genes |
| B. | unidentifiable, chromosome |
| C. | identifiable, chromosome |
| D. | identifiable, genes |
| Answer» D. identifiable, genes | |
| 26. |
Which of the following is untrue about the genome mapping? |
| A. | It doesn’t lead to the understanding a genome structure |
| B. | It involves identifying relative locations of genes |
| C. | It involves identifying traits |
| D. | It involves identifying mutations |
| Answer» B. It involves identifying relative locations of genes | |