Explore topic-wise MCQs in Bioinformatics.

This section includes 12 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the following is incorrect regarding GeneQuiz?

A. It is a web server for protein DNA annotation
B. It is a web server for protein sequence annotation
C. It compares a query sequence against databases using BLAST and FASTA to identify homologs with high similarities
D. It performs domain analysis using the PROSITE and Blocks databases
Answer» B. It is a web server for protein sequence annotation
Discussion
2.

In some circumstances, one mRNA transcript can lead to the translation of more than one protein.

A. True
B. False
Answer» B. False
Discussion
3.

Conserved functional sites can be identified by profile and hidden Markov model–based motif and domain search tools such as SMART and InterPro.

A. True
B. False
Answer» B. False
Discussion
4.

Which of the following is incorrect regarding gene ontology?

A. It exists because there is a need to standardize protein functional descriptions
B. It uses a limited vocabulary to describe molecular functions
C. Biological processes are not described though
D. The cellular components are described using limited vocabulary
Answer» D. The cellular components are described using limited vocabulary
Discussion
5.

IN_SOME_CIRCUMSTANCES,_ONE_MRNA_TRANSCRIPT_CAN_LEAD_TO_THE_TRANSLATION_OF_MORE_THAN_ONE_PROTEIN.?$

A. True
B. False
Answer» B. False
Discussion
6.

Which_of_the_following_is_incorrect_regarding_GeneQuiz?$

A. It is a web server for protein DNA annotation
B. It is a web server for protein sequence annotation
C. It compares a query sequence against databases using BLAST and FASTA to identify homologs with high similarities
D. It performs domain analysis using the PROSITE and Blocks databases
Answer» B. It is a web server for protein sequence annotation
Discussion
7.

Which of the following is incorrect regarding genome economy?

A. It is a phenomenon of synthesizing more proteins from fewer genes
B. This is a major strategy that eukaryotic organisms use to achieve a myriad of genotypic diversities only
C. This is a major strategy that eukaryotic organisms use to achieve a myriad of phenotypic diversities
D. There are numerous underlying genetic mechanisms to help account for genome economy
Answer» C. This is a major strategy that eukaryotic organisms use to achieve a myriad of phenotypic diversities
Discussion
8.

The remote homology detection helps to shed light on the possible functions of the proteins that previously have no functional information at all.

A. True
B. False
Answer» B. False
Discussion
9.

Conserved functional sites can be identified by profile and hidden Markov model–based motif and domain search tools such as SMART and InterPro.$

A. True
B. False
Answer» B. False
Discussion
10.

Which of the following is incorrect regarding Automated Genome Annotation?

A. It exists because of the need to develop fast and automated methods to annotate the genomic sequences
B. The automated approach relies on homology detection
C. The automated approach doesn’t rely on heuristic sequence similarity searching
D. Automation brings speed in gene annotation process
Answer» D. Automation brings speed in gene annotation process
Discussion
11.

Which of the following is incorrect regarding gene annotation?

A. The gene annotation of the human genome employs a combination of theoretical prediction and experimental verification
B. Gene structures are first predicted by ab initio exon prediction programs
C. The predicted genes are compared with experimentally determined cDNA and EST sequences
D. The pairwise alignment programs are not involved
Answer» E.
Discussion
12.

The genome annotation process involves two steps: gene prediction and functional assignment.

A. True
B. False
Answer» B. False
Discussion