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This section includes 6 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
Which of the following is untrue about Prediction Using Discriminant Analysis for Gene Prediction? |
A. | QDA draws a curved line based on a quadratic function |
B. | LDA works by drawing a diagonal line that best separates coding signals from noncoding signals based on knowledge learned from training data sets of known gene structures |
C. | Some gene prediction algorithms rely on discriminant analysis, either LDA or quadratic discriminant analysis (QDA), to improve accuracy |
D. | LDA works by plotting a three-dimensional graph of coding signals versus all potential 3 splice site positions |
Answer» E. | |
2. |
GRAIL is a web-based program that is based on a neural network algorithm Which is trained on several statistical features such as splice junctions, start and stop codons, poly-A sites, promoters, and CpG islands. |
A. | True |
B. | False |
Answer» B. False | |
3. |
Which of the following is untrue about Prediction Using Neural Networks for Gene Prediction? |
A. | A neural network is constructed with multiple layers; the input, output, and hidden layers |
B. | The input is the gene sequence with intron and exon signals |
C. | The model is not fed with a sequence of known gene structure |
D. | The output is the probability of an exon structure |
Answer» D. The output is the probability of an exon structure | |
4. |
In Ab Initio Based Programs for Gene Prediction Gene content refers to coding statistics, which includes nonrandom nucleotide distribution, amino acid distribution, synonymous codon usage, and hexamer frequencies. |
A. | True |
B. | False |
Answer» B. False | |
5. |
Which of the following is untrue about Ab Initio Based Programs for Gene Prediction? |
A. | The goal of the ab initio gene prediction programs is to discriminate exons from noncoding sequences |
B. | The goal is joining exons together in the correct order |
C. | The main difficulty is correct identification of exons |
D. | To predict exons, the algorithms rely solely on gene signals |
Answer» E. | |
6. |
Most vertebrate genes use __________ as the translation start codon and have a uniquely conserved flanking sequence call a Kozak sequence (CCGCCATGG). |
A. | AAG |
B. | ATG |
C. | AUG |
D. | AGG |
Answer» C. AUG | |