Explore topic-wise MCQs in Bioinformatics.

This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

The second step in phylogenetic analysis is to construct sequence alignment. This is probably the most critical step in the procedure because it establishes positional correspondence in evolution.

A. True
B. False
Answer» B. False
Discussion
2.

To obtain a species phylogeny, phylogenetic trees from a variety of gene families need to be constructed.

A. True
B. False
Answer» B. False
Discussion
3.

The second step in phylogenetic analysis is to construct sequence alignment. This is probably the most critical step in the procedure because it establishes positional correspondence in evolution?

A. True
B. False
Answer» B. False
Discussion
4.

Which of the following is incorrect statement about Choosing Substitution Models?

A. There is one substitution at a particular position, in divergent sequences
B. The evolutionary divergence is beyond the ability of the statistical models to correct
C. The statistical models used to correct homoplasy are called substitution models or evolutionary models
D. For constructing DNA phylogenies, there are nucleotide substitution models available
Answer» B. The evolutionary divergence is beyond the ability of the statistical models to correct
Discussion
5.

Which of the following is incorrect statement about the Kimura model?

A. It is a model to correct evolutionary distances and is a more sophisticated model
B. In this, the mutation rates for transitions and transversion are assumed to be different
C. According to this model, occur more frequently than transversions
D. According to this model, transversions occur more frequently than transitions
Answer» E.
Discussion
6.

It is often desirable to define the root of a tree. There are two ways to define the root of a tree. One is to use an outgroup, which ______

A. is a sequence that is homologous to the sequences under consideration
B. is separated from those sequences at an early evolutionary time
C. is generally determined from independent sources of information
D. is generally determined from similar or related sources of information
Answer» E.
Discussion
7.

To obtain a species phylogeny, phylogenetic trees from a variety of gene families need to be constructed

A. True
B. False
Answer» B. False
Discussion
8.

The species evolution is the ______ of evolution by _____ in a genome.

A. combined result, multiple genes
B. result, single genes
C. result, sole genes
D. distinct results, single gene
Answer» B. result, single genes
Discussion
9.

Evolution of a particular sequence _______ correlate with the evolutionary path of the species.

A. does not
B. always
C. does not necessarily
D. invariably
Answer» D. invariably
Discussion
10.

A gene phylogeny only describes the evolution of a particular gene or encoded protein.

A. True
B. False
Answer» B. False
Discussion