 
			 
			MCQOPTIONS
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				This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | PIWI proteins have been best studied in _________________ | 
| A. | mice | 
| B. | fruit flies | 
| C. | nematodes | 
| D. | maize | 
| Answer» C. nematodes | |
| 2. | Which type of RNAs suppress the movement of transposons in the germline? | 
| A. | mRNAs | 
| B. | piRNAs | 
| C. | miRNAs | 
| D. | tRNAs | 
| Answer» C. miRNAs | |
| 3. | Drosha is an ___________________ | 
| A. | enzyme | 
| B. | micro RNA | 
| C. | messenger RNA | 
| D. | satellite DNA | 
| Answer» B. micro RNA | |
| 4. | Micro RNAs participate in ______________ | 
| A. | posttranslational modification | 
| B. | posttranscriptional modification | 
| C. | chromatin remodeling | 
| D. | gene silencing | 
| Answer» E. | |
| 5. | Which of the following RNAs are highly conserved? | 
| A. | let-1 | 
| B. | pet-1 | 
| C. | let-7 | 
| D. | pet-7 | 
| Answer» D. pet-7 | |
| 6. | The first RNAi therapeutics was aimed at treating ______________________ | 
| A. | muscular dystrophy | 
| B. | macular degeneration | 
| C. | multiple myeloma | 
| D. | neurodegeneration | 
| Answer» C. multiple myeloma | |
| 7. | What takes place when siRNAs are used in place of dsRNA in mammalian cells? | 
| A. | gene knock-down | 
| B. | apoptosis | 
| C. | necrosis | 
| D. | aggregation | 
| Answer» B. apoptosis | |
| 8. | RNA interference is not observed in vertebrates. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 9. | Which family of proteins plays a key role in gene silencing pathways? | 
| A. | Globulin | 
| B. | Argonaute | 
| C. | Intein-containing proteins | 
| D. | Amino-acyl transferases | 
| Answer» C. Intein-containing proteins | |
| 10. | Dicer converts double-stranded RNAs into _______________ | 
| A. | snRNA | 
| B. | siRNA | 
| C. | mRNA | 
| D. | tRNA | 
| Answer» C. mRNA | |
| 11. | RNA interference is evolved as a genetic immune system. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 12. | The phenomenon of RNA interference was discovered using the organism ___________________ | 
| A. | Mus musculus | 
| B. | Drosophila | 
| C. | C. elegans | 
| D. | Arabidopsis thaliana | 
| Answer» D. Arabidopsis thaliana | |
| 13. | The studies that led to discovery of posttranscriptional gene silencing phenomena were performed on ____________ | 
| A. | petunia | 
| B. | sunflower | 
| C. | maize | 
| D. | wheat | 
| Answer» B. sunflower | |
| 14. | When was it first discovered that RNA molecules are capable of catalyzing chemical reactions? | 
| A. | 1962 | 
| B. | 1972 | 
| C. | 1982 | 
| D. | 1992 | 
| Answer» D. 1992 | |