Explore topic-wise MCQs in Bioinformatics.

This section includes 11 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the given statement is incorrect about the Chromosomal Rearrangements?

A. Comparison of the number of rearrangements in a given period of evolutionary history may vary significantly from one organism to the next
B. If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, there is an increased probability of an ortholog of B also occurring in the other organism
C. If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, the B ortholog is more likely to be a neighbor of the A ortholog of the genome of the second species if the two species are more divergent
D. In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity
Answer» D. In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity
2.

Two species that have recently diverged from a common ancestor might be expected to have a ________ set of genes and ________ chromosomes with these genes positioned along the chromosomes in the same order.

A. distinct, similar
B. similar, distinct
C. similar, dissimilar
D. similar, similar
Answer» E.
3.

WHICH_OF_THE_GIVEN_STATEMENT_IS_INCORRECT_ABOUT_THE_CHROMOSOMAL_REARRANGEMENTS??$

A. Comparison of the number of rearrangements in a given period of evolutionary history may vary significantly from one organism to the next
B. If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, there is an increased probability of an ortholog of B also occurring in the other organism
C. If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, the B ortholog is more likely to be a neighbor of the A ortholog of the genome of the second species if the two species are more divergent
D. In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity
Answer» D. In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity
4.

Which of the given statement is incorrect about the observations made with regard to gene order?

A. Order is highly conserved in closely related species
B. Order in closely related species becomes changed by rearrangements over evolutionary time
C. As more and more rearrangements occur, there will no longer be any correspondence in the order of orthologous genes on the chromosome of one organism with that of a second organism
D. Order is less conserved in closely related species
Answer» E.
5.

Two species that have recently diverged from a common ancestor might be expected to have a ____ set of genes and _____ chromosomes with these genes positioned along the chromosomes in the same order.

A. distinct, similar
B. similar, distinct
C. similar, dissimilar
D. similar, similar
Answer» E.
6.

Other functional classification schemes for genes include a broader category for genes involved in the same biological process, e.g., a three-group scheme for energy-related, information-related, and communication-related genes has also been used.

A. True
B. False
Answer» B. False
7.

An approach to classification of genes that encode enzymes is to examine relationships among multiple enzymes that perform the same biochemical function in the same organism.

A. True
B. False
Answer» B. False
8.

The designation ECa.b.c.d conveys information. Which of the following is not one of it?

A. One of twelve main classes of biochemical reactions
B. The group of substrate molecule
C. The nature of chemical bond that is involved in the reaction
D. Designation for acceptor molecules (cofactors)
Answer» B. The group of substrate molecule
9.

Which of the given statement is incorrect?

A. paralogous sequences, frequently are found to have dissimilar functions
B. An early classification scheme for eight related groups of E. coli genes included categories for enzymes, transport elements
C. An early classification scheme for eight related groups of E. coli genes included categories for regulators, membranes, structural elements, protein factors, leader peptides, and carriers
D. Ninety percent of E. coli genes related by significant sequence similarity fell into these same broad categories
Answer» B. An early classification scheme for eight related groups of E. coli genes included categories for enzymes, transport elements
10.

Which of the given statement is incorrect regarding MAGPIE?

A. It analyzes the genome using a set of automated processes
B. It is designed for high-throughput genome sequence analysis
C. It is unable to locate potential promoters
D. It automatically annotates genomic sequence data and maintains a daily up-to-date record in response to user queries about one or more genomes
Answer» D. It automatically annotates genomic sequence data and maintains a daily up-to-date record in response to user queries about one or more genomes
11.

GeneQuiz focuses on deriving a predicted protein function, based on a variety of available evidence, including the evaluation of the similarity to the closest homolog in a database.

A. True
B. False
Answer» B. False