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This section includes 11 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the given statement is incorrect about the Chromosomal Rearrangements? |
| A. | Comparison of the number of rearrangements in a given period of evolutionary history may vary significantly from one organism to the next |
| B. | If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, there is an increased probability of an ortholog of B also occurring in the other organism |
| C. | If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, the B ortholog is more likely to be a neighbor of the A ortholog of the genome of the second species if the two species are more divergent |
| D. | In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity |
| Answer» D. In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity | |
| 2. |
Two species that have recently diverged from a common ancestor might be expected to have a ________ set of genes and ________ chromosomes with these genes positioned along the chromosomes in the same order. |
| A. | distinct, similar |
| B. | similar, distinct |
| C. | similar, dissimilar |
| D. | similar, similar |
| Answer» E. | |
| 3. |
WHICH_OF_THE_GIVEN_STATEMENT_IS_INCORRECT_ABOUT_THE_CHROMOSOMAL_REARRANGEMENTS??$ |
| A. | Comparison of the number of rearrangements in a given period of evolutionary history may vary significantly from one organism to the next |
| B. | If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, there is an increased probability of an ortholog of B also occurring in the other organism |
| C. | If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, the B ortholog is more likely to be a neighbor of the A ortholog of the genome of the second species if the two species are more divergent |
| D. | In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity |
| Answer» D. In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identity | |
| 4. |
Which of the given statement is incorrect about the observations made with regard to gene order? |
| A. | Order is highly conserved in closely related species |
| B. | Order in closely related species becomes changed by rearrangements over evolutionary time |
| C. | As more and more rearrangements occur, there will no longer be any correspondence in the order of orthologous genes on the chromosome of one organism with that of a second organism |
| D. | Order is less conserved in closely related species |
| Answer» E. | |
| 5. |
Two species that have recently diverged from a common ancestor might be expected to have a ____ set of genes and _____ chromosomes with these genes positioned along the chromosomes in the same order. |
| A. | distinct, similar |
| B. | similar, distinct |
| C. | similar, dissimilar |
| D. | similar, similar |
| Answer» E. | |
| 6. |
Other functional classification schemes for genes include a broader category for genes involved in the same biological process, e.g., a three-group scheme for energy-related, information-related, and communication-related genes has also been used. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 7. |
An approach to classification of genes that encode enzymes is to examine relationships among multiple enzymes that perform the same biochemical function in the same organism. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 8. |
The designation ECa.b.c.d conveys information. Which of the following is not one of it? |
| A. | One of twelve main classes of biochemical reactions |
| B. | The group of substrate molecule |
| C. | The nature of chemical bond that is involved in the reaction |
| D. | Designation for acceptor molecules (cofactors) |
| Answer» B. The group of substrate molecule | |
| 9. |
Which of the given statement is incorrect? |
| A. | paralogous sequences, frequently are found to have dissimilar functions |
| B. | An early classification scheme for eight related groups of E. coli genes included categories for enzymes, transport elements |
| C. | An early classification scheme for eight related groups of E. coli genes included categories for regulators, membranes, structural elements, protein factors, leader peptides, and carriers |
| D. | Ninety percent of E. coli genes related by significant sequence similarity fell into these same broad categories |
| Answer» B. An early classification scheme for eight related groups of E. coli genes included categories for enzymes, transport elements | |
| 10. |
Which of the given statement is incorrect regarding MAGPIE? |
| A. | It analyzes the genome using a set of automated processes |
| B. | It is designed for high-throughput genome sequence analysis |
| C. | It is unable to locate potential promoters |
| D. | It automatically annotates genomic sequence data and maintains a daily up-to-date record in response to user queries about one or more genomes |
| Answer» D. It automatically annotates genomic sequence data and maintains a daily up-to-date record in response to user queries about one or more genomes | |
| 11. |
GeneQuiz focuses on deriving a predicted protein function, based on a variety of available evidence, including the evaluation of the similarity to the closest homolog in a database. |
| A. | True |
| B. | False |
| Answer» B. False | |