MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which type of macromolecules make up the wall of microtubules? |
| A. | globular proteins |
| B. | glycoproteins |
| C. | deoxyribonucleic acids |
| D. | carbohydrates |
| Answer» B. glycoproteins | |
| 2. |
How many protofilaments are present in a single mammalian microtubule? |
| A. | 5 |
| B. | 13 |
| C. | 20 |
| D. | 26 |
| Answer» C. 20 | |
| 3. |
Where in a eukaryotic cell, can a microtubule NOT be found? |
| A. | flagella |
| B. | mitotic spindle |
| C. | nucleus |
| D. | cilia |
| Answer» D. cilia | |
| 4. |
All the protofilaments of a microtubule have the same _____________ |
| A. | polarity |
| B. | pH |
| C. | fluorescence |
| D. | torque |
| Answer» B. pH | |
| 5. |
Neurofibrillary tangles, found in the brain cells of persons with neurodegenerative disorders consists of _______________ |
| A. | intermediate filaments |
| B. | microtubule-associated proteins |
| C. | microtubules |
| D. | phospholipids |
| Answer» C. microtubules | |
| 6. |
Alpha-tubulin subunits terminate the plus end of the microtubule. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 7. |
Colcemid is a drug that acts on ___________ |
| A. | myosin |
| B. | kinesin |
| C. | tubulin |
| D. | colchicine |
| Answer» D. colchicine | |
| 8. |
Myosins VIII and _____ are present only in plant cells. |
| A. | IX |
| B. | X |
| C. | XI |
| D. | XII |
| Answer» D. XII | |
| 9. |
Absence of the intermediate filament desmin, has a negative impact on _______________ |
| A. | hepatocytes |
| B. | nerve cells |
| C. | epithelial cells |
| D. | muscle cells |
| Answer» E. | |
| 10. |
Smallest microtubular motor proteins are __________________ |
| A. | dyeneins |
| B. | niacin |
| C. | thiamine |
| D. | kinesin |
| Answer» E. | |
| 11. |
Cilia and flagella are ________________ |
| A. | intermediate filaments |
| B. | microfilaments |
| C. | microtubules |
| D. | phospholipids |
| Answer» C. microtubules | |
| 12. |
Which of the following acts as an attractant for axons? |
| A. | netrin |
| B. | porphyrin |
| C. | integrin |
| D. | laminin |
| Answer» B. porphyrin | |
| 13. |
The Wiskott-Aldrich syndrome is caused due the lack of functional ____________ protein. |
| A. | ActA |
| B. | Arf1 |
| C. | WASP |
| D. | WAVE |
| Answer» D. WAVE | |
| 14. |
According to “Sliding filament model of muscle contraction”, shortening of sacromeres results from sliding of the filaments. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 15. |
ActA, a surface protein activates the ______________ |
| A. | Arp2/3 complex |
| B. | Sar1 |
| C. | Arf1 |
| D. | EcoR1 |
| Answer» B. Sar1 | |
| 16. |
Intermediate filaments are _________________ |
| A. | heterogenous |
| B. | homogenous |
| C. | labile |
| D. | weak |
| Answer» B. homogenous | |
| 17. |
Aggregation of neurofilaments leads to ____________ |
| A. | vision disorders |
| B. | skin disorders |
| C. | lung disorders |
| D. | neurodegenerative disorders |
| Answer» E. | |
| 18. |
Which of the following has an opposing role as that of thymosin? |
| A. | chymosin |
| B. | vimentin |
| C. | profilin |
| D. | niacin |
| Answer» D. niacin | |
| 19. |
Unlike other cytoskeletal elements, in the assembly of intermediate filaments there is no requirement of ______________ |
| A. | ATP/ GDP |
| B. | Nucleation |
| C. | Reduction |
| D. | Hydrolysis |
| Answer» B. Nucleation | |
| 20. |
Movement of materials in an axon are mediated through ________________ that serve as cytoskeletal tracks. |
| A. | microtubules |
| B. | actin filaments |
| C. | microfilaments |
| D. | intermediate filaments |
| Answer» B. actin filaments | |
| 21. |
Which motor protein superfamily does not move along the microtubules? |
| A. | Dynein |
| B. | Kinesin |
| C. | Myosin |
| D. | Calmodulin |
| Answer» D. Calmodulin | |
| 22. |
The identification of actin filaments in a cell can be done by using the protein ____________ |
| A. | myosin |
| B. | kinesin |
| C. | globulin |
| D. | vimentin |
| Answer» B. kinesin | |
| 23. |
In total internal reflection microscopy (TIRF), thin planes can be focused. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 24. |
The protein responsible for muscular dystrophy, dystrophin, is a __________ protein. |
| A. | cross-linking |
| B. | membrane-binding |
| C. | tethering |
| D. | severing |
| Answer» C. tethering | |
| 25. |
The phenomenon of “treadmilling” is observed in microfilaments under the __________ state. |
| A. | steady |
| B. | isotonic |
| C. | hypertonic |
| D. | thermodynamically favorable |
| Answer» B. isotonic | |
| 26. |
Intermediate filaments tend to be less sensitive to __________________ |
| A. | chemicals |
| B. | plectins |
| C. | acidification |
| D. | condensation |
| Answer» B. plectins | |
| 27. |
Cross-linking proteins villin and fimbrin are found in ___________ |
| A. | neurons |
| B. | myoblasts |
| C. | microvilli |
| D. | flagella |
| Answer» D. flagella | |
| 28. |
Which is a type of intermediate filament found in epithelial cells? |
| A. | keratin |
| B. | dynein |
| C. | myosin |
| D. | kinesin |
| Answer» B. dynein | |
| 29. |
Changes in cell shape occur due to changes in the orientation of cytoskeletal elements. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 30. |
The microtubule-binding activity of MAPs is controlled by ______________ |
| A. | phosphorylation |
| B. | oxidation |
| C. | reduction |
| D. | hydrolysis |
| Answer» B. oxidation | |
| 31. |
Monomer-sequestering proteins are responsible for high concentration of G-actin in nonmuscle cells. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 32. |
In fluorescence speckle microscopy, cytoskeletal filaments are uniformly labeled. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 33. |
________ of the sacromere remains unaffected during the muscle contraction. |
| A. | H zone |
| B. | A band |
| C. | I band |
| D. | H band |
| Answer» C. I band | |
| 34. |
Troponin is composed of _____ subunits. |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» D. 4 | |
| 35. |
Which of the following are the most extensible filaments? |
| A. | intermediate filaments |
| B. | cytochrome |
| C. | microfilaments |
| D. | microtubules |
| Answer» B. cytochrome | |
| 36. |
Intermediate filaments lack polarity. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 37. |
The type V intermediate filaments are called ___________ |
| A. | lamins |
| B. | collagen |
| C. | lignin |
| D. | fibrin |
| Answer» B. collagen | |
| 38. |
Outer microtubules in a cilium are generated from ______________ |
| A. | basal body |
| B. | centromere |
| C. | centrosome |
| D. | nucleus |
| Answer» B. centromere | |
| 39. |
Which of the following are found only in animal cells? |
| A. | intermediate filaments |
| B. | microtubules |
| C. | nucleus |
| D. | microfilaments |
| Answer» B. microtubules | |
| 40. |
The drug colchicine promotes microtubule _____________ |
| A. | disassembly |
| B. | assembly |
| C. | acidification |
| D. | condensation |
| Answer» B. assembly | |
| 41. |
Ciliopathies were first identified in model organisms _________________ |
| A. | C. elegans |
| B. | Drososphila |
| C. | Mus musculus |
| D. | Arabidopsis thaliana |
| Answer» B. Drososphila | |
| 42. |
The striated appearance of muscle fibers is due to _______________ |
| A. | nucleus |
| B. | sacromeres |
| C. | sarcoma |
| D. | myoblasts |
| Answer» C. sarcoma | |
| 43. |
Which technique has been used to study the dynamic nature of microtubules? |
| A. | AFM |
| B. | FRAP |
| C. | GC-MS |
| D. | ICP-MS |
| Answer» C. GC-MS | |
| 44. |
Melanosomes are transferred into the developing hair by myosin ____ |
| A. | II |
| B. | III |
| C. | IV |
| D. | V |
| Answer» E. | |
| 45. |
How many cytoplasmic dyneins are present in eukaryotic cells? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 46. |
Variants of a protein are called __________ |
| A. | isotopes |
| B. | isomers |
| C. | isoforms |
| D. | enantiomers |
| Answer» D. enantiomers | |
| 47. |
Which types of lasers are used in optical tweezers? |
| A. | Laser beams |
| B. | UV-rays |
| C. | X-rays |
| D. | Radio waves |
| Answer» B. UV-rays | |
| 48. |
Which of the following nucleating protein generates unbranched actin filaments? |
| A. | formin |
| B. | kinesin |
| C. | globulin |
| D. | vimentin |
| Answer» B. kinesin | |
| 49. |
Intermediate filaments are branched structures. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 50. |
Which of the following proteins are not found in muscle fibres? |
| A. | keratin |
| B. | actin |
| C. | troponin |
| D. | tropomyosin |
| Answer» B. actin | |