MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
COPI-coated vesicles move the materials in __________________ direction. |
| A. | retrograde |
| B. | anterograde |
| C. | radial |
| D. | lateral |
| Answer» B. anterograde | |
| 2. |
Dynamin is a _____________________ |
| A. | adaptor molecule |
| B. | accessory protein |
| C. | integral membrane protein |
| D. | phospholipids |
| Answer» C. integral membrane protein | |
| 3. |
GFP joined at the end of a protein can interfere in its synthesis. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 4. |
What of the following molecules is not transported through the secretory pathway of endomembrane system? |
| A. | nucleic acids |
| B. | complex polysaccharides |
| C. | proteins |
| D. | lipids |
| Answer» B. complex polysaccharides | |
| 5. |
GTP-bound ‘Rabs’ (G-proteins) associated with membranes by a __________ anchor. |
| A. | lipid |
| B. | protein |
| C. | carbohydrate |
| D. | ribonucleic acid |
| Answer» B. protein | |
| 6. |
In regulated secretion, materials are __________ |
| A. | secreted |
| B. | stored |
| C. | degraded |
| D. | aggregated |
| Answer» C. degraded | |
| 7. |
Which type of endomembrane secretion occurs in nerve cells? |
| A. | constitutive |
| B. | regulatory |
| C. | non-continuous |
| D. | intermittent |
| Answer» C. non-continuous | |
| 8. |
Where do the materials ingested by endocytosis, reach after travelling through the late endosome? |
| A. | nucleus |
| B. | lysosome |
| C. | mitochondria |
| D. | early endosome |
| Answer» C. mitochondria | |
| 9. |
Receptors dissociate from their bound ligands as a result of ________________ |
| A. | high H⁺ concentration |
| B. | low H⁺ concentration |
| C. | high Cl¯ concentration |
| D. | low Cl¯ concentration |
| Answer» B. low H⁺ concentration | |
| 10. |
Endocytosis and phagocytosis refer to the same process. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 11. |
Which of the following can be used as a temperature-sensitive mutant to study the endomembrane system? |
| A. | Vesicular Stomatitis Virus |
| B. | Human Immunodeficiency Virus |
| C. | Tobacco Mosaic Virus |
| D. | Retrovirus |
| Answer» B. Human Immunodeficiency Virus | |
| 12. |
Which technique was used to study the secretory pathway in acinar cells of the pancreas for the first time? |
| A. | Gel electrophoresis |
| B. | Chromatography |
| C. | Autoradiography |
| D. | ELISA |
| Answer» D. ELISA | |
| 13. |
RNAi phenomenon inhibits the synthesis of which biomolecules? |
| A. | RNA |
| B. | DNA |
| C. | Proteins |
| D. | Carbohydrates |
| Answer» D. Carbohydrates | |
| 14. |
Mitochondrial matrix proteins have a target sequence, called presequence located at __________ |
| A. | N-terminus |
| B. | C-terminus |
| C. | interstitial site |
| D. | center of the sequence |
| Answer» B. C-terminus | |
| 15. |
Late endosomes are located near the _____________ |
| A. | membrane |
| B. | nucleus |
| C. | mitochondria |
| D. | peroxisomes |
| Answer» C. mitochondria | |
| 16. |
ARF1 is a _______ binding protein. |
| A. | carbohydrate |
| B. | GTP |
| C. | GDP |
| D. | ATP |
| Answer» C. GDP | |
| 17. |
In the endocytic pathway, materials are discharged from the cell. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 18. |
Kupffer cells are located in the _________ |
| A. | kidney |
| B. | lungs |
| C. | liver |
| D. | intestine |
| Answer» D. intestine | |
| 19. |
After the digestive process in an autophagolysosome is over, it is termed as _______________ |
| A. | autophagosome |
| B. | residual body |
| C. | endosome |
| D. | peroxisome |
| Answer» C. endosome | |
| 20. |
Which of the following are the targets of bacterial toxins botulism and tetanus? |
| A. | Sar1 |
| B. | SNAREs |
| C. | Rabs |
| D. | ARF1 |
| Answer» C. Rabs | |
| 21. |
What is responsible for the transport of materials from the cis cisternae to the trans cisternae of the Golgi complex? |
| A. | active diffusion |
| B. | passive diffusion |
| C. | translocon |
| D. | transport vesicles |
| Answer» E. | |
| 22. |
While moving from cis cisternae to the trans cisternae, which molecule does not leave the cisternal lumen? |
| A. | membrane proteins |
| B. | procollagen |
| C. | oligosaccharides |
| D. | lysosomal proteins |
| Answer» C. oligosaccharides | |
| 23. |
A protein coat of diameter ________ is present on the transport vesicles. |
| A. | 0.5-1 mm |
| B. | 0.5-1 nm |
| C. | 0.5-1 pm |
| D. | 0.5-1 μm |
| Answer» E. | |
| 24. |
Hsp 70 and Hsp 90 are ____________ involved in the mitochondrial uptake of proteins. |
| A. | chaperones |
| B. | receptors |
| C. | ligands |
| D. | glycolipids |
| Answer» B. receptors | |
| 25. |
Which molecule activates the formation of a transport vesicle? |
| A. | G-protein |
| B. | Lactose |
| C. | DNA helicase |
| D. | Inducer |
| Answer» B. Lactose | |
| 26. |
COPII-coated vesicles move the materials from ____________ to ____________ |
| A. | ERGIC, Golgi complex |
| B. | Golgi complex, ERGIC |
| C. | ER, Golgi complex |
| D. | Golgi complex, ER |
| Answer» D. Golgi complex, ER | |
| 27. |
In how many subcompartments of the chloroplasts, can the proteins be delivered? |
| A. | 2 |
| B. | 4 |
| C. | 6 |
| D. | 8 |
| Answer» D. 8 | |
| 28. |
Following its entry into the mitochondrial matrix, the peptide is _______________ |
| A. | degraded |
| B. | converted to phagosome |
| C. | folded to its native conformation |
| D. | hydrolyzed |
| Answer» D. hydrolyzed | |
| 29. |
‘Stroma targeting domain’ is located in the ________________ |
| A. | chloroplast |
| B. | mitochondria |
| C. | peptide |
| D. | transit peptide |
| Answer» E. | |
| 30. |
Most proteins destined for uptake by the chloroplasts are synthesized with a ________________ |
| A. | removable C-terminal sequence |
| B. | removable N-terminal sequence |
| C. | removable hydrophobic tail |
| D. | removable hydrophilic tail |
| Answer» C. removable hydrophobic tail | |
| 31. |
How many models of movement of materials through the Golgi complex exist? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 32. |
Newly synthesized membrane proteins enter the cis face of the Golgi complex and leave from the trans face. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 33. |
Which protein families do not mechanically support the Golgi complex? |
| A. | Keratin |
| B. | Actin |
| C. | Spectrin |
| D. | Ankyrin |
| Answer» B. Actin | |
| 34. |
Which of the following is not completely synthesized in the Golgi complex of a cell? |
| A. | Pectins |
| B. | Hemicellulose |
| C. | N-linked oligosaccharides |
| D. | O-linked oligosaccharides |
| Answer» D. O-linked oligosaccharides | |
| 35. |
Which of the following is located at the trans end of the Golgi stack? |
| A. | ascorbic acid |
| B. | methanoic acid |
| C. | sialyl-transferase |
| D. | dehydrogenase |
| Answer» D. dehydrogenase | |
| 36. |
The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment. |
| A. | hydrolyzed bonds |
| B. | hydrophobic bonds |
| C. | disulfide bonds |
| D. | hydrophilic bonds |
| Answer» D. hydrophilic bonds | |
| 37. |
Which of the following enzyme present in the rough endoplasmic reticulum removes the signal sequence from nascent polypeptides? |
| A. | signal oxidase |
| B. | signal peptidase |
| C. | olisaccharyltransferase |
| D. | luciferase |
| Answer» C. olisaccharyltransferase | |
| 38. |
In yeast cells, protein transport across the endoplasmic reticulum membrane occurs __________ |
| A. | perpendicularly |
| B. | discontinuously |
| C. | co-translationally |
| D. | post-translationally |
| Answer» E. | |
| 39. |
Translocon is a ____________ |
| A. | polypeptide |
| B. | protein channel |
| C. | receptor |
| D. | recognition particle |
| Answer» C. receptor | |
| 40. |
In mammalian cells, the signal recognition particle (SRP) consists of ____ distinct polypeptides and one small RNA molecule. |
| A. | 2 |
| B. | 4 |
| C. | 6 |
| D. | 8 |
| Answer» D. 8 | |
| 41. |
Glycolipids are synthesized in the ER and ____________ |
| A. | Nucleus |
| B. | Golgi complex |
| C. | Mitochondrion |
| D. | Plasma membrane |
| Answer» C. Mitochondrion | |
| 42. |
Hydrophobic transmembrane segments of which proteins are not synthesized in the endoplasmic reticulum? |
| A. | integral membrane proteins |
| B. | lysosomal proteins |
| C. | steroids |
| D. | secretory proteins |
| Answer» B. lysosomal proteins | |
| 43. |
Which of the following parts of Golgi complex directs the proteins to their final intracellular destinations? |
| A. | tubules |
| B. | cis-Golgi network |
| C. | trans-Golgi network |
| D. | medial cisternae |
| Answer» D. medial cisternae | |
| 44. |
Cis-Golgi network (CGN) is closer to the endoplasmic reticulum than the trans-Golgi network (TGN). |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 45. |
Golgi complex has a cisternae of diameter _________ |
| A. | 0.5-1 mm |
| B. | 0.5-1 nm |
| C. | 0.5-1 pm |
| D. | 0.5-1 μm |
| Answer» E. | |
| 46. |
Sarcoplasmic reticulum is found in ________________ |
| A. | liver cells |
| B. | kidney cells |
| C. | muscle cells |
| D. | neurons |
| Answer» D. neurons | |
| 47. |
All the cells contain the same ratio of rough and smooth endoplasmic reticulum. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 48. |
The signal sequence that determines whether a protein will be synthesized on a free ribosome or ribosome attached to endoplasmic reticulum is located at _______ |
| A. | N-terminal |
| B. | C-terminal |
| C. | hydrophobic tail |
| D. | hydrophilic tail |
| Answer» B. C-terminal | |
| 49. |
Which enzymes are responsible for detoxification of organic compounds carried out by the smooth endoplasmic reticulum? |
| A. | Dehydrogenases |
| B. | Oxygenases |
| C. | Nucleases |
| D. | Ribonucleases |
| Answer» C. Nucleases | |
| 50. |
Detoxification of organic compounds like barbiturates and ethanol in the liver is carried out by ________________ |
| A. | smooth endoplasmic reticulum |
| B. | sarcoplasmic reticulum |
| C. | rough endoplasmic reticulum |
| D. | nucleus |
| Answer» B. sarcoplasmic reticulum | |