14 + Mcqs in Conformational Flexibility Page 1 McqOptions

Explore topic-wise MCQs in Bioinformatics.

Which of the following is true regarding Protein flexibility?

Stochastic methods can guarantee reaching a global optimal solution and the methods are computationally costly in comparison to the other methods.

Genetic methods (genetic algorithms and evolutionary programming) store multiple solutions. These solutions form a population of members.

In a Monte Carlo simulation the score (or energy) is calculated at each step and compared to the previous step. The probability of accepting the step is given by _________ where ΔE is the difference in energy; kB is Boltzmann’s constant and T the temperature.

The disadvantage of Multiple conformation rigid-body method is that the active conformation may be missed as the result of a minor structural difference not considered in the ______ ligand conformations. Where, the N is the number of low-energy conformations.

STOCHASTIC_METHODS_CAN_GUARANTEE_REACHING_A_GLOBAL_OPTIMAL_SOLUTION_AND_THE_METHODS_ARE_COMPUTATIONALLY_COSTLY_IN_COMPARISON_TO_THE_OTHER_METHODS.?$

Which_of_the_following_is_true_regarding_Protein_flexibility?$

Genetic methods (genetic algorithms and evolutionary programming) store multiple solutions. These solutions form a population of members?

In Stochastic search methods, they include methods such as Monte Carlo simulation, simulated annealing, Tabu search, genetic algorithms and evolutionary programming.

The disadvantage of Multiple conformation rigid-body method is that the active conformation may be missed as the result of a minor structural difference not considered in the ___ ligand conformations. Where, the N is the number of low-energy conformations.

In Multiple conformation rigid-body method, a ligand is assumed to be able to adopt a number (N) of different ___ that are computed _ the ligand being docked into the receptor.

In case of Protein-ligand docking, __ ligands are often _ in adapting their shape to fit the receptor binding pocket.

Typical motions of proteins will be primarily treated by a rigid body model for docking.

Proteins are dynamic entities that undergo _______

Explore topic-wise MCQs in Bioinformatics.

Which of the following is true regarding Protein flexibility?

Stochastic methods can guarantee reaching a global optimal solution and the methods are computationally costly in comparison to the other methods.

Genetic methods (genetic algorithms and evolutionary programming) store multiple solutions. These solutions form a population of members.

In a Monte Carlo simulation the score (or energy) is calculated at each step and compared to the previous step. The probability of accepting the step is given by _________ where ΔE is the difference in energy; kB is Boltzmann’s constant and T the temperature.

The disadvantage of Multiple conformation rigid-body method is that the active conformation may be missed as the result of a minor structural difference not considered in the ______ ligand conformations. Where, the N is the number of low-energy conformations.

STOCHASTIC_METHODS_CAN_GUARANTEE_REACHING_A_GLOBAL_OPTIMAL_SOLUTION_AND_THE_METHODS_ARE_COMPUTATIONALLY_COSTLY_IN_COMPARISON_TO_THE_OTHER_METHODS.?$

Which_of_the_following_is_true_regarding_Protein_flexibility?$

Genetic methods (genetic algorithms and evolutionary programming) store multiple solutions. These solutions form a population of members?

In Stochastic search methods, they include methods such as Monte Carlo simulation, simulated annealing, Tabu search, genetic algorithms and evolutionary programming.

The disadvantage of Multiple conformation rigid-body method is that the active conformation may be missed as the result of a minor structural difference not considered in the ___ ligand conformations. Where, the N is the number of low-energy conformations.

In Multiple conformation rigid-body method, a ligand is assumed to be able to adopt a number (N) of different _______ that are computed _____ the ligand being docked into the receptor.

In case of Protein-ligand docking, ______ ligands are often _____ in adapting their shape to fit the receptor binding pocket.

Typical motions of proteins will be primarily treated by a rigid body model for docking.

Proteins are dynamic entities that undergo _______

In Multiple conformation rigid-body method, a ligand is assumed to be able to adopt a number (N) of different ___ that are computed _ the ligand being docked into the receptor.

In case of Protein-ligand docking, __ ligands are often _ in adapting their shape to fit the receptor binding pocket.