Explore topic-wise MCQs in Bioinformatics.

This section includes 11 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

RBS finder is a UNIX program that uses the prediction output from Glimmer and searches for the Shine–Delgarno sequences in the vicinity of predicted start sites.

A. True
B. False
Answer» B. False
Discussion
2.

In the ab initio–based approaches—they rely on two major features associated with genes: one of them being gene content, which is statistical description of coding regions.

A. True
B. False
Answer» B. False
Discussion
3.

In the ab initio–based approaches—they rely on two major features associated with genes: one of them being the existence of gene signals, which include start and stop codons, intron splice signals, transcription factor binding sites, etc.

A. True
B. False
Answer» B. False
Discussion
4.

RBS finder is a UNIX program that uses the prediction output from Glimmer and searches for the Shine–Delgarno sequences in the vicinity of predicted start sites?#

A. True
B. False
Answer» B. False
Discussion
5.

Which of the following is untrue about Glimmer?

A. It stands for Gene Locator and Interpolated Markov Modeler
B. It is a UNIX program from TIGR
C. It does not necessarily use the IMM algorithm
D. It is used to predict potential coding regions
Answer» D. It is used to predict potential coding regions
Discussion
6.

Which of the following is untrue about GeneMark?

A. It is a suite of gene prediction programs based on the fifth-order HMMs
B. The main program is trained on a number of complete microbial genomes
C. A GeneMark heuristic program can be used to improve accuracy
D. If the sequence to be predicted is from a non-listed organism, the most closely related organism can be chosen as the basis for computation
Answer» D. If the sequence to be predicted is from a non-listed organism, the most closely related organism can be chosen as the basis for computation
Discussion
7.

FGENESB is a web-based program that is also based on fifth-order HMMs for detecting coding regions.

A. True
B. False
Answer» B. False
Discussion
8.

The homology-based method makes predictions based on significant matches of the query sequence with sequences of known genes.

A. True
B. False
Answer» B. False
Discussion
9.

In the ab initio–based approaches—they rely on two major features associated with genes: one of them being gene content, which is statistical description of coding regions.$

A. True
B. False
Answer» B. False
Discussion
10.

In the ab initio–based approaches—they rely on two major features associated with genes: one of them being the existence of gene signals, which include start and stop codons, intron splice signals, transcription factor binding sites etc$

A. True
B. False
Answer» B. False
Discussion
11.

Which of the following is true regarding the methods of gene prediction?

A. They solely consist of a type called ab initio–based methods
B. The ab initio–based approach predicts genes based on the given sequence alone
C. The ab initio–based approach predicts genes based on the given sequence and relative homology data
D. They solely consist of a type called homology-based approaches
Answer» C. The ab initio‚Äö√Ñ√∂‚àö√ë‚àö¬®based approach predicts genes based on the given sequence and relative homology data
Discussion