Explore topic-wise MCQs in Bioinformatics.

This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

Unlike the commonly used methods for aligning a pair of sequences, the Bayesian method _______ using a particular scoring matrix or designated gap penalties.

A. does not depend on
B. depends on
C. is based on
D. involves
Answer» B. depends on
2.

Zhu (1998) have devised a computer program called the Bayes block aligner which in effect slides ____ sequences along each other to find the ______ ungapped regions or blocks.

A. two, least scoring
B. two, highest scoring
C. multiple, highest scoring
D. multiple, least scoring
Answer» C. multiple, highest scoring
3.

Another difficulty in Bayesian methods is deciding on the length of sequence that was duplicated.

A. True
B. False
Answer» B. False
4.

In Bayesian methods, difficulty with making estimations is that the estimate depends on the following Assumption. (Assumption – The mutation rate in sequences has been constant with time and that the rate of mutation of all nucleotides is the same.)

A. True
B. False
Answer» B. False
5.

ZHU_(1998)_HAVE_DEVISED_A_COMPUTER_PROGRAM_CALLED_THE_BAYES_BLOCK_ALIGNER_WHICH_IN_EFFECT_SLIDES______SEQUENCES_ALONG_EACH_OTHER_TO_FIND_THE________UNGAPPED_REGIONS_OR_BLOCKS.?$

A. two, least scoring
B. two, highest scoring
C. multiple, highest scoring
D. multiple, least scoring
Answer» C. multiple, highest scoring
6.

Unlike_the_commonly_used_methods_for_aligning_a_pair_of_sequences,_the_Bayesian_method_________using_a_particular_scoring_matrix_or_designated_gap_penalties.$

A. does not depend on
B. depends on
C. is based on
D. involves
Answer» B. depends on
7.

Which of the following feature of Bayesian methods is the disadvantage of it?

A. A length and distance that gives the highest overall probability may be determined
B. They are used to calculate evolutionary distance
C. Computationally Bayesian methods are better
D. A specific mutational model is required
Answer» E.
8.

A length and distance that gives the highest overall probability may then be determined. Such alignments are initially found using ________

A. a particular scoring matrix only
B. an alignment algorithm only
C. an alignment algorithm and a particular scoring matrix
D. dot method
Answer» D. dot method
9.

Another difficulty in Bayesian methods is deciding on the length of sequence that was duplicated

A. True
B. False
Answer» B. False
10.

In Bayesian methods, difficulty with making estimations is that the estimate depends on the

A.
B. True
Answer» B. True
11.

In a type of probability, analysis is to calculate the odds score for one event OR a second event, or of a series of events. In this case, the odds scores are _______

A. multiplied
B. subtracted
C. added and multiplied
D. added
Answer» E.
12.

If the purpose is to calculate the probability of one event AND a second event, the odds scores for the events are _________

A. added
B. multiplied
C. multiplied and added
D. subtracted
Answer» C. multiplied and added
13.

With the application of Bayesian methods, the most probable repeat length and evolutionary time since the repeat was formed may be derived.

A. True
B. False
Answer» B. False
14.

By whom and when were the Bayesian methods applied first?

A. Smith-Waterman, 1981
B. Agarwal and States, 1996
C. Smith-Waterman, 1996
D. Agarwal and States, 1981
Answer» C. Smith-Waterman, 1996