Dayhoff, 1978- 1983, devised a second method for testing the relatedness of two protein sequences that can accommodate some local variation. Where this method is useful?

For finding repeated regions within a sequence

For finding similar regions that are in a different order in two sequences

For finding small conserved region such as an active site

For finding huge regions within sequences

On analysis of the alignment scores of random sequences will reveal that the scores follow a different distribution than the normal distribution called the _________

Gumbel equal value distribution

Gumbel extreme value distribution

Explore topic-wise MCQs in Bioinformatics.

This section includes 4 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.	Dayhoff, 1978- 1983, devised a second method for testing the relatedness of two protein sequences that can accommodate some local variation. Where this method is useful?
A.	For finding repeated regions within a sequence
B.	For finding similar regions that are in a different order in two sequences
C.	For finding small conserved region such as an active site
D.	For finding huge regions within sequences
Answer» E.

Discussion

2.	The GCG alignment programs have a RANDOMIZATION option, which shuffles the second sequence and calculates similarity scores between the unshuffled sequence and each of the shuffled copies.
A.	True
B.	False
Answer» B. False

Discussion

3.	If the random sequences were prepared in a way that maintained the local base composition by producing them from overlapping fragments of sequence, the distribution of scores has a _______ standard deviation that is closer to the distribution of the natural sequences.
A.	lowest
B.	higher
C.	lower
D.	moderate
Answer» D. moderate

Discussion

4.	On analysis of the alignment scores of random sequences will reveal that the scores follow a different distribution than the normal distribution called the _________
A.	Gumbel equal value distribution
B.	Gumbel extreme value distribution
C.	Gumbel end value distribution
D.	Gumbel distribution
Answer» C. Gumbel end value distribution

Discussion

Explore topic-wise MCQs in Bioinformatics.

Dayhoff, 1978- 1983, devised a second method for testing the relatedness of two protein sequences that can accommodate some local variation. Where this method is useful?

The GCG alignment programs have a RANDOMIZATION option, which shuffles the second sequence and calculates similarity scores between the unshuffled sequence and each of the shuffled copies.

If the random sequences were prepared in a way that maintained the local base composition by producing them from overlapping fragments of sequence, the distribution of scores has a _______ standard deviation that is closer to the distribution of the natural sequences.

On analysis of the alignment scores of random sequences will reveal that the scores follow a different distribution than the normal distribution called the _________