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This section includes 4 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Dayhoff, 1978- 1983, devised a second method for testing the relatedness of two protein sequences that can accommodate some local variation. Where this method is useful? |
| A. | For finding repeated regions within a sequence |
| B. | For finding similar regions that are in a different order in two sequences |
| C. | For finding small conserved region such as an active site |
| D. | For finding huge regions within sequences |
| Answer» E. | |
| 2. |
The GCG alignment programs have a RANDOMIZATION option, which shuffles the second sequence and calculates similarity scores between the unshuffled sequence and each of the shuffled copies. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
If the random sequences were prepared in a way that maintained the local base composition by producing them from overlapping fragments of sequence, the distribution of scores has a _______ standard deviation that is closer to the distribution of the natural sequences. |
| A. | lowest |
| B. | higher |
| C. | lower |
| D. | moderate |
| Answer» D. moderate | |
| 4. |
On analysis of the alignment scores of random sequences will reveal that the scores follow a different distribution than the normal distribution called the _________ |
| A. | Gumbel equal value distribution |
| B. | Gumbel extreme value distribution |
| C. | Gumbel end value distribution |
| D. | Gumbel distribution |
| Answer» C. Gumbel end value distribution | |