Which of the following statement is incorrect regarding germ theory of diseases postulated by Robert Koch?

• A. A specific organism can always be found in association with a given disease
• B. The organism can be isolated and grown in pure culture in the laboratories
• C. The pure culture cannot produce the disease when inoculated into susceptible animal however the causative organism isolated from pure culture can do so.
• D. It is possible to recover the organism in pure culture from the experimentally infected animals.