1.

Which of the following is untrue about Homology-Based Programs?

A. They are based on the fact that exon structures and exon sequences of related species are less conserved
B. This approach assumes that the database sequences are correct
C. It is a reasonable assumption in light of the fact that many homologous sequences to be compared with are derived from cDNA or expressed sequence tags (ESTs) of the same species
D. Potential coding frames in a query sequence are translated and used to align with closest protein homologs found in databases
Answer» B. This approach assumes that the database sequences are correct


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