Originally, the FOLD program of _____ predicted _____ having the minimum free energy.

Originally, the FOLD program of _____ predicted _____ having the minim

1.	Originally, the FOLD program of _____ predicted _____ having the minimum free energy.
A.	M. Zuker, two structures
B.	M. Wunsch, two structures
C.	M. Zuker, only one
D.	M. Wunsch, only one
Answer» D. M. Wunsch, only one

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These limitations of the Zuker method and other methods have been largely overcome by using an algorithm originally described by Waterman and Byers (1985) for finding sequence alignments within a certain range of the optimal one by modifications of the trace-back procedure used in dynamic programming.
A limitation of the Zuker method and other methods (Nakaya et al. 1995) for computing suboptimal RNA structures is that they do not compute all the structures within a given energy range of the minimum free-energy structure.
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j. Which of the following is not a correct regarding Ssum?
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j. Which of the following is not a correct regarding Hnum?
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j. Which of the following is not a correct regarding Pnum?
In the programs related to FOLD, All complementary base pairs can be sampled in a fashion to determine which are present in a suboptimal structure.
In the programs related to FOLD, the second region, the ________ region, is used to calculate the energy of the ________ structure.
A_LIMITATION_OF_THE_ZUKER_METHOD_AND_OTHER_METHODS_(NAKAYA_ET_AL._1995)_FOR_COMPUTING_SUBOPTIMAL_RNA_STRUCTURES_IS_THAT_THEY_DO_NOT_COMPUTE_ALL_THE_STRUCTURES_WITHIN_A_GIVEN_ENERGY_RANGE_OF_THE_MINIMUM_FREE-ENERGY_STRUCTURE.?$
These_limitations_of_the_Zuker_method_and_other_methods_have_been_largely_overcome_by_using_an_algorithm_originally_described_by_Waterman_and_Byers_(1985)_for_finding_sequence_alignments_within_a_certain_range_of_the_optimal_one_by_modifications_of_the_trace-back_procedure_used_in_dynamic_programming.$
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j.

Originally, the FOLD program of _ predicted _ having the minimum free energy.

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