1.

Oligonucleotides are synthesized chemically. Which of the following step is involved in oligonucleotide synthesis?

A. Nucleotide addition is done by adding many nucleotides at a time
B. The coupling reaction should involve water
C. Only one type of nucleotides can be added at a time
D. Unblocking of the reactive groups leads to addition of nucleotides
Answer» E.


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