Mrs.Shilla, 27 yrs, put on weight (10kg over a period of 3 years),and has oligomenorrhoea followed by amenorrohoea for 10 months.The blood pressure is 160/100 mm of Hg.Which is the most appropriate investigation?

• A. Plasma cortisol
• B. Serum electrolytes
• C. T3,T4,and TSH
• D. Plasma testosterone and ultrasound evaluation of pelvis