Choose the correct statement if the screening is carried out by screening by expression in vivo.

• A. The proportion of recombinants carrying gene of interest is small
• B. The recombinants carrying gene of interest don‚Äö√Ñ√∂‚àö√ë‚àö¬•t complement the host mutation
• C. Mutation should be affecting many genes
• D. Most of the products selected would be result of complementation