1.

A nine month old boy of Sindhi parents presented to you with complains of progressive lethargy, irritability and pallor since 6 month of age.Examination revealed severe pallor.Investigation showed Hb-3.8 mg%;MCV-58fi;MCH-19.4pg/cell.Blood film shows osmotic fragility is normal (target cells and normoblasts).X-ray skull shows expansion of erythroid marrow.Which of the following is the most likely diagnosis?

A. Hemoglobin D disease
B. Hereditary spherocytosis
C. Iron deficiency anemia
D. Acute lymphoblastic anemia
Answer» D. Acute lymphoblastic anemia


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