A 40 year old male patient is hospitalised with huge splenomegaly, marked sternal tenderness, and a total leucocyte count of 85000 per cubic millimetre with large percentage of myeocytes and meta myelocytes, which one of the following drugs is best indicated for his disease ?

• A. Chlorambucil
• B. Cyclophosphamide
• C. Hydroxyurea
• D. Melphation