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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Vector Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
ADENOVIRUS_VECTORS_CAN_BE_USED_FOR_____________CELLS_SUCH_AS_NEURONS.?$ |
A. | Somatic |
B. | Germ |
C. | Totipotent |
D. | Post-mitotic |
Answer» E. | |
2. |
The deletion of which genes in an Adenovirus vector precludes the immunological effects?$ |
A. | E7 |
B. | E2 |
C. | E3 |
D. | E4 |
Answer» E. | |
3. |
Adenovirus-derived_vaccines_have_been_used_in_humans_with_no_reported_side-effects.$ |
A. | True |
B. | False |
Answer» B. False | |
4. |
What happens to the AAV DNA in the absence of helper virus? |
A. | Does not infect the cell |
B. | Does not integrate |
C. | Integrates into host genome |
D. | Cannot synthesize proteins |
Answer» D. Cannot synthesize proteins | |
5. |
AAV is naturally __________ |
A. | Translation defective |
B. | Replication defective |
C. | Small in size |
D. | Lacking attachment ability |
Answer» C. Small in size | |
6. |
Adeno-associated Virus was actually first discovered as a ___________ |
A. | Contaminant |
B. | Human virus |
C. | Insect virus |
D. | Phage |
Answer» B. Human virus | |
7. |
Insertion_of_stuffer_DNA_into_which_of_the_gene_keeps_recombination_from_happening? |
A. | E1 |
B. | E2 |
C. | E3 |
D. | E4 |
Answer» D. E4 | |
8. |
Adenovirus vectors are useful for short-term transgene expression because ____________? |
A. | Inefficient integration |
B. | Efficient integration |
C. | High stability |
D. | Small size |
Answer» B. Efficient integration | |
9. |
Retrovirus is an example of ____________ virus. |
A. | Plant |
B. | Icosahedral |
C. | Hybrid |
D. | Binary |
Answer» C. Hybrid | |
10. |
Which of the following is an example of rod-shaped virus? |
A. | Baculovirus |
B. | Papillomavirus |
C. | Adenovirus |
D. | Retrovirus |
Answer» B. Papillomavirus | |
11. |
The advantage of “gutless vectors” is that they possess no intrinsic cytotoxic effects.$ |
A. | True |
B. | False |
Answer» B. False | |
12. |
Which element in the amplicons is responsible for packaging? |
A. | Trans |
B. | Cis |
C. | Amp |
D. | Cysteine |
Answer» C. Amp | |
13. |
What are amplicons? |
A. | Gut-less vectors |
B. | Hybrid vectors |
C. | Helper virus |
D. | Helper phage |
Answer» B. Hybrid vectors | |
14. |
Usage of “packaging lines” is an alternative to __________$ |
A. | Cloning |
B. | Recombination |
C. | Co-introduction of helper virus |
D. | Viral vector for gene transfer |
Answer» D. Viral vector for gene transfer | |
15. |
In the case of helper-dependent viral vectors, what does the helper virus contain? |
A. | Homeotic genes |
B. | Origin |
C. | Transposon |
D. | Missing genes |
Answer» E. | |