MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Vector Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
What happens to the AAV DNA in the absence of helper virus? |
| A. | Does not infect the cell |
| B. | Does not integrate |
| C. | Integrates into host genome |
| D. | Cannot synthesize proteins |
| Answer» D. Cannot synthesize proteins | |
| 2. |
AAV is naturally __________ |
| A. | Translation defective |
| B. | Replication defective |
| C. | Small in size |
| D. | Lacking attachment ability |
| Answer» C. Small in size | |
| 3. |
Adeno-associated Virus was actually first discovered as a ___________ |
| A. | Contaminant |
| B. | Human virus |
| C. | Insect virus |
| D. | Phage |
| Answer» B. Human virus | |
| 4. |
Insertion of stuffer DNA into which of the gene keeps recombination from happening? |
| A. | E1 |
| B. | E2 |
| C. | E3 |
| D. | E4 |
| Answer» D. E4 | |
| 5. |
The deletion of which genes in an Adenovirus vector precludes the immunological effects? |
| A. | E7 |
| B. | E2 |
| C. | E3 |
| D. | E4 |
| Answer» E. | |
| 6. |
Adenovirus-derived vaccines have been used in humans with no reported side-effects. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 7. |
Adenovirus vectors can be used for ___________ cells such as neurons. |
| A. | Somatic |
| B. | Germ |
| C. | Totipotent |
| D. | Post-mitotic |
| Answer» E. | |
| 8. |
Adenovirus vectors are useful for short-term transgene expression because _____________ |
| A. | Inefficient integration |
| B. | Efficient integration |
| C. | High stability |
| D. | Small size |
| Answer» B. Efficient integration | |
| 9. |
Retrovirus is an example of ____________ virus. |
| A. | Plant |
| B. | Icosahedral |
| C. | Hybrid |
| D. | Binary |
| Answer» C. Hybrid | |
| 10. |
Which of the following is an example of rod-shaped virus? |
| A. | Baculovirus |
| B. | Papillomavirus |
| C. | Adenovirus |
| D. | Retrovirus |
| Answer» B. Papillomavirus | |
| 11. |
The advantage of “gutless vectors” is that they possess no intrinsic cytotoxic effects. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 12. |
Which element in the amplicons is responsible for packaging? |
| A. | Trans |
| B. | Cis |
| C. | Amp |
| D. | Cysteine |
| Answer» C. Amp | |
| 13. |
What are amplicons? |
| A. | Gut-less vectors |
| B. | Hybrid vectors |
| C. | Helper virus |
| D. | Helper phage |
| Answer» B. Hybrid vectors | |
| 14. |
Usage of “packaging lines” is an alternative to __________ |
| A. | Cloning |
| B. | Recombination |
| C. | Co-introduction of helper virus |
| D. | Viral vector for gene transfer |
| Answer» D. Viral vector for gene transfer | |
| 15. |
In the case of helper-dependent viral vectors, what does the helper virus contain? |
| A. | Homeotic genes |
| B. | Origin |
| C. | Transposon |
| D. | Missing genes |
| Answer» E. | |