MCQOPTIONS
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MCQOPTIONS
This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Vector Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
THE_ENDOGENOUS_SELECTABLE_MARKERS_CAN_BE_USED_ONLY_WITH_MUTANT_CELL_LINES.?$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
HSV_TK_GENE_IS_A_TYPE_OF____________MARKER.?$ |
| A. | Exogenous |
| B. | Endogenous |
| C. | Recombinant |
| D. | Hybrid |
| Answer» C. Recombinant | |
| 3. |
What are the dominant selectable markers?$ |
| A. | Drug-resistance genes |
| B. | Inducing genes |
| C. | Exogenous genes |
| D. | Endogenous genes |
| Answer» B. Inducing genes | |
| 4. |
Dominant selectable markers can be used with __________$ |
| A. | Any cell type |
| B. | Mutant cells |
| C. | Wild-type cells |
| D. | Recombinant cells |
| Answer» B. Mutant cells | |
| 5. |
One application in which the use of plasmid vectors is critical, in the case of mammals is ____________ |
| A. | Stable transformation |
| B. | Transient transformation |
| C. | Transfection |
| D. | Transduction |
| Answer» C. Transfection | |
| 6. |
With respect to mammalian cell cloning, salmon sperm DNA can serve as a source of ____________ |
| A. | Non-specific carrier |
| B. | Specific carrier |
| C. | Genomic DNA |
| D. | Plasmid DNA |
| Answer» B. Specific carrier | |
| 7. |
What is the prerequisite for co-transformation phenomenon to occur? |
| A. | Selectable marker |
| B. | HSV |
| C. | Thymidine kinase |
| D. | PBR322 DNA |
| Answer» B. HSV | |
| 8. |
Southern blot hybridization is done for testing the presence of _________ in a selection of transformants. |
| A. | Non-selected DNA |
| B. | Selected plasmid DNA |
| C. | Genomic DNA |
| D. | Selected genomic DNA |
| Answer» B. Selected plasmid DNA | |
| 9. |
What do you understand by the term “co-transformation”?$ |
| A. | Integration of 2 transgenes |
| B. | Integration of similar transgenes |
| C. | Integration of a group of transgenes |
| D. | Integration of chromosomal DNA |
| Answer» B. Integration of similar transgenes | |
| 10. |
The drug aminopterin blocks the _________ of two enzymes. |
| A. | Salvage pathway |
| B. | De novo synthesis |
| C. | Expression |
| D. | Recombination |
| Answer» C. Expression | |
| 11. |
De novo pathway is exploited for the selection of cells carrying functional HPRT and TK genes. |
| A. | True |
| B. | False |
| Answer» C. | |
| 12. |
In the salvage pathway, nucleotides are synthesized by the recycling of ___________ |
| A. | DNA |
| B. | RNA |
| C. | DNA, RNA |
| D. | Sugars |
| Answer» D. Sugars | |
| 13. |
What are the basic precursors in the de novo pathway of nucleotide synthesis? |
| A. | Carbohydrate, proteins |
| B. | Sugars, amino acids |
| C. | Sugars, vitamins |
| D. | Minerals, carbohydrates |
| Answer» C. Sugars, vitamins | |
| 14. |
How many routes are available for the biosynthesis of nucleotides in human beings? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |