MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Vector Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Insect cell lines derived from Estigmene area have the ability of __________ |
| A. | tPost-translational modification |
| B. | tReplication |
| C. | tTransduction |
| D. | tConjugation |
| Answer» B. tReplication | |
| 2. |
One limitation of baculovirus expressed system is that ___________ in mammals and insects is different. |
| A. | tGlycosylation pathway |
| B. | tGenomic size |
| C. | tCloning efficiency |
| D. | tVirus genre |
| Answer» B. tGenomic size | |
| 3. |
Bombyx mori nuclear polyhedrosis virus infects the _______ |
| A. | tDrosophila |
| B. | tPlants |
| C. | tHumans |
| D. | tSilkworm |
| Answer» E. | |
| 4. |
AcMNPV vector is a type of __________ which is used for expression in insect cells. |
| A. | tBaculoviruses |
| B. | tAdenoviruses |
| C. | tCaulimoviruses |
| D. | tPapillomavirus |
| Answer» B. tAdenoviruses | |
| 5. |
The polyhedrin gene of baculovirus vectors cannot be replaced by foreign DNA. |
| A. | tTrue |
| B. | tFalse |
| Answer» C. | |
| 6. |
Which protein is expressed at high levels in occlusion bodies of baculoviruses? |
| A. | tPolyhedron |
| B. | tAmylose |
| C. | tGlucose |
| D. | tLactose |
| Answer» B. tAmylose | |
| 7. |
Nuclear occlusion bodies are _____________ |
| A. | tNuclear particles |
| B. | tVitamins |
| C. | tProteinaceous particles |
| D. | tReplication genes |
| Answer» D. tReplication genes | |
| 8. |
Nuclear occlusion bodies are found in _______________ |
| A. | tBaculoviruses |
| B. | tAdenovirus |
| C. | tHuman somatic cells |
| D. | tHuman germ cells |
| Answer» B. tAdenovirus | |
| 9. |
Use of con-catemeric replication intermediates, circumvents which of the most serious disadvantage of AAV vectors? |
| A. | tReplication ability |
| B. | tInfection cycle |
| C. | tDNA carrying capacity |
| D. | tHost range |
| Answer» D. tHost range | |
| 10. |
Which of the following type of cells cannot be transfected by AAV vector? |
| A. | tLiver cells |
| B. | tGerm cells |
| C. | tMuscle cells |
| D. | tNeurons |
| Answer» C. tMuscle cells | |
| 11. |
Deletion of which region of an AAV vector abolishes the site-specificity? |
| A. | tOrigin of replication |
| B. | tCap region |
| C. | tRep region |
| D. | tInverted repeats |
| Answer» D. tInverted repeats | |
| 12. |
Either endogenous or homologous promoters can be used with an AAV vector. |
| A. | tTrue |
| B. | tFalse |
| Answer» B. tFalse | |
| 13. |
Which is the only element essential for replication in an AAV vector? |
| A. | tOrigin of replication |
| B. | tInverted repeats |
| C. | tRep genes |
| D. | tCap genes |
| Answer» D. tCap genes | |
| 14. |
Where is foreign DNA inserted in an AAV virus vector? |
| A. | tCap region |
| B. | tRep region |
| C. | tInverted repeats |
| D. | tOrigin of replication |
| Answer» D. tOrigin of replication | |
| 15. |
Why is AAV regarded as one of the safest vectors for gene therapy? |
| A. | tLack origin |
| B. | tHelper virus dependent |
| C. | tSmall sized genome |
| D. | tNo toxic effects |
| Answer» C. tSmall sized genome | |