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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Vector Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
What happens if an essential gene is replaced in a viral vector? |
A. | tHelper dependent |
B. | tHelper independent |
C. | tNon-function |
D. | tLoss of transfection ability |
Answer» B. tHelper independent | |
2. |
Helper-independent vectors can _____________ |
A. | tNot Propagate |
B. | tPropagate dependently |
C. | tPropagate independently |
D. | tTransduce the cell |
Answer» D. tTransduce the cell | |
3. |
Virus particles have a natural ability of ___________ |
A. | tAdsorbing on the cell surface |
B. | tProliferation |
C. | tInducing tumor |
D. | tInducing apoptosis |
Answer» B. tProliferation | |
4. |
Apart from the introduction of DNA into cultured cells, bacteria mediated gene transfer has also been used for ________ |
A. | tRecombinant protein production |
B. | tTransgenic animal |
C. | tIn vivo gene transfer |
D. | tIn vitro gene transfer |
Answer» D. tIn vitro gene transfer | |
5. |
Attenuation of Listeria Monocytogenes can be achieved by ___________ |
A. | tAuxotrophic strains |
B. | tAutolysis |
C. | tGene knockout |
D. | tMutation |
Answer» C. tGene knockout | |
6. |
Inducible autolysis is a technique for attenuation. |
A. | tTrue |
B. | tFalse |
Answer» B. tFalse | |
7. |
AroA mutants are unable to synthesize _____________ |
A. | tAmino acids |
B. | tHomeotic genes |
C. | tVitamins |
D. | tAromatic compounds |
Answer» E. | |
8. |
Which of the following is a technique of bacterial attenuation? |
A. | tAuxotrophic mutants |
B. | tRemoval of cell wall |
C. | tProtoplast fusion |
D. | tConjugation |
Answer» B. tRemoval of cell wall | |
9. |
What would happen if attenuated bacteria are not used for mammalian gene transfer? |
A. | tCell death |
B. | tTumor |
C. | tProliferation |
D. | tUnsuccessful gene transfer |
Answer» B. tTumor | |
10. |
Which is an important principle in gene transfer using live bacteria? |
A. | tAmplification |
B. | tAttenuation |
C. | tLysis |
D. | tPhagocytosis |
Answer» C. tLysis | |
11. |
Pilus helps in the transfer of DNA through a process of ___________ |
A. | tTransduction |
B. | tTransfection |
C. | tConjugation |
D. | tTransformation |
Answer» D. tTransformation | |
12. |
Which of the following occurs in DNA transfer by A. Tumefaciens? |
A. | tCell lysis |
B. | tConjugation |
C. | tInfection |
D. | tMyeloma |
Answer» C. tInfection | |
13. |
In the cases of Salmonella species, lysis occurs in the __________ |
A. | tOutside the phagocytic vesicle |
B. | tInside the phagocytic vesicle |
C. | tIn lymphatic system |
D. | tIn nucleus |
Answer» C. tIn lymphatic system | |
14. |
Which of the following is an artificial form of bactofection? |
A. | tTransduction |
B. | tProtoplast fusion |
C. | tBolistics |
D. | tElectroporation |
Answer» C. tBolistics | |
15. |
Agrobacterium tumefaciens can transfer DNA to animal cells. |
A. | tTrue |
B. | tFalse |
Answer» B. tFalse | |