MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Vector Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Resistance to SIV and HIV-2 was shown by infecting _______ with Vaccinia vectors. |
| A. | tCow |
| B. | tPlants |
| C. | tDrosophila |
| D. | tMouse |
| Answer» E. | |
| 2. |
Vaccinia viruses expressing the influenza hemagglutinin gene were used to immunize ____________ |
| A. | tHamsters |
| B. | tHumans |
| C. | tRabbits |
| D. | tCow |
| Answer» B. tHumans | |
| 3. |
Which cells were transfected in an early demonstration that vaccinia virus could be used to express antigens from other infectious agents? |
| A. | tHuman cells |
| B. | tInsect cells |
| C. | tPlant cells |
| D. | tMonkey cells |
| Answer» E. | |
| 4. |
The vaccinia virus cannot be used to express antigens from other infectious agents. |
| A. | tTrue |
| B. | tFalse |
| Answer» C. | |
| 5. |
A useful binary expression system contains Vaccinia virus and bacteriophage ________ |
| A. | tT7 |
| B. | tT5 |
| C. | tT8 |
| D. | tT9 |
| Answer» B. tT5 | |
| 6. |
Which of the following sequence must be removed from DNA expressed in Vaccinia vectors? |
| A. | tTTTTTNT |
| B. | tTTTTTTT |
| C. | tNNNNNNN |
| D. | tTNTNTNT |
| Answer» B. tTTTTTTT | |
| 7. |
Vaccinia vectors cannot be used to express genes with __________ |
| A. | tExons |
| B. | tJunk DNA |
| C. | tViral components |
| D. | tIntrons |
| Answer» E. | |
| 8. |
Highest expression levels in Vaccinia vectors are produced by ______ promoters. |
| A. | tP11 |
| B. | tP7.5 |
| C. | t4b |
| D. | tP10 |
| Answer» B. tP7.5 | |
| 9. |
Transgene expression in vaccinia vectors depends on ___________ |
| A. | tExogenous promoter |
| B. | tEndogenous promoter |
| C. | tEndogenous inducer |
| D. | tExogenous inducer |
| Answer» C. tEndogenous inducer | |
| 10. |
LacZ is a screenable marker used with Vaccinia vectors. |
| A. | tTrue |
| B. | tFalse |
| Answer» B. tFalse | |
| 11. |
NEO is a type of ____________ |
| A. | tSelectable marker |
| B. | tScreenable marker |
| C. | tPromoter |
| D. | tInducer |
| Answer» B. tScreenable marker | |
| 12. |
When transgene is inserted into the viral hemagglutinin locus, wild-type plaques turn ________ |
| A. | tRed |
| B. | tWhite |
| C. | tBlue |
| D. | tClear |
| Answer» B. tWhite | |
| 13. |
5-bromodeoxyuridine is an analog of ___________ |
| A. | tPyrimidine |
| B. | tAlanine |
| C. | tValine |
| D. | tThymidine |
| Answer» E. | |
| 14. |
Why are recombinant genomes of poxyvirus non-infectious? |
| A. | tVirus packages its own DNA |
| B. | tHost packages viral DNA |
| C. | tDNA remains unpacked |
| D. | tVirus packages unpacked |
| Answer» B. tHost packages viral DNA | |
| 15. |
What is the reason for a large genome of poxyvirus? |
| A. | tEncodes for all human genes |
| B. | tEncodes for replication machinery |
| C. | tEncodes all promoters |
| D. | tContains a large portion of junk DNA |
| Answer» C. tEncodes all promoters | |