MCQOPTIONS
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MCQOPTIONS
This section includes 5 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In an experiment you add increasing amount of sigma factor to a mixture of DNA fragment and core polymerase in vitro. You also add [14C]ATP and [ -32P]ATP in the mixture and check the rate of incorporation. Results show that the incorporation of both of this labels increase on adding more sigma factor. What will you conclude from your observation? |
| A. | Sigma confers specificity and increases transcription rate |
| B. | Sigma increases initiation and elongation rate |
| C. | Sigma increases initiation of transcription rate |
| D. | Sigma causes faster elongation |
| Answer» C. Sigma increases initiation of transcription rate | |
| 2. |
Mutations as far as 100 base pairs upstream to +1 site will also affect the transcription rate. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
In an experiment you mutate the C terminal domain of alpha subunit of the RNA polymerase. What will you expect to see? |
| A. | Transcription is absent |
| B. | Transcription is at random sites |
| C. | Transcription is less |
| D. | Transcription is more |
| Answer» D. Transcription is more | |
| 4. |
The catalytic unit of RNA polymerases when placed properly during initiation is just over _________ |
| A. | -1 site |
| B. | 0 site |
| C. | +1 site |
| D. | 10 site |
| Answer» D. 10 site | |
| 5. |
Which of these is the 1st event to take place during transcription initiation? |
| A. | Formation of a closed initiation complex |
| B. | Formation of open initiation complex |
| C. | Formation of absorptive transcript |
| D. | Promoter clearance |
| Answer» C. Formation of absorptive transcript | |