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This section includes 19 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
1. |
RNA pol II will be isolated from the nuclear parts outside the nucleolus. |
A. | True |
B. | False |
Answer» B. False | |
2. |
The rRNA primary transcript is located in________ |
A. | Nucleus |
B. | NOR |
C. | Cytoplasm |
D. | Nuclear pore |
Answer» C. Cytoplasm | |
3. |
Which of the following is not a normal processing step of the tRNA? |
A. | The 3’ end U is replaced by CCA |
B. | The Purines are methylated and isopentyl groups are transferred to them |
C. | The 3’ OH is methylated |
D. | U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine |
Answer» D. U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine | |
4. |
The 5’ end of the tRNA transcript is cleaved by____________ |
A. | RNase K |
B. | Exonuclease VII |
C. | Endonucleace I |
D. | Rnase P |
Answer» E. | |
5. |
Which one of the following characters doesn’t go along with tRNA? |
A. | Its primary transcript is processed by proteins |
B. | The cleavage at the 5’ and 3’ end of the intron is simultaneous |
C. | The introns are seen in yeast and they are larger than exons |
D. | ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns |
Answer» D. ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns | |
6. |
The pre-rRNA transcript transcribed by the RNA pol Idoesn’t include_________ |
A. | 18S |
B. | 5S |
C. | 5.8S |
D. | 28S |
Answer» C. 5.8S | |
7. |
WHICH_OF_THE_FOLLOWING_IS_NOT_A_NORMAL_PROCESSING_STEP_OF_THE_TRNA??$ |
A. | The 3’ end U is replaced by CCA |
B. | The Purines are methylated and isopentyl groups are transferred to them |
C. | The 3’ OH is methylated |
D. | U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine |
Answer» D. U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine | |
8. |
RNA pol II will be isolated from the nuclear parts outside the nucleolus.$ |
A. | True |
B. | False |
Answer» B. False | |
9. |
The rRNA primary transcript is located in________$ |
A. | Nucleus |
B. | NOR |
C. | Cytoplasm |
D. | Nuclear pore |
Answer» C. Cytoplasm | |
10. |
The 45S rRNA transcript is first broken into ______________ |
A. | 32S and 20S |
B. | 19S and 36S |
C. | 6S and 40S |
D. | 32S, 20s and 7S |
Answer» B. 19S and 36S | |
11. |
The 5’ end of the tRNA transcript is cleaved by___________?# |
A. | RNase K |
B. | Exonuclease VII |
C. | Endonucleace I |
D. | Rnase P |
Answer» E. | |
12. |
Which one of the following characters doesn’t go along with tRNA?$ |
A. | Its primary transcript is processed by proteins |
B. | The cleavage at the 5’ and 3’ end of the intron is simultaneous |
C. | The introns are seen in yeast and they are larger than exons |
D. | ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns |
Answer» D. ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns | |
13. |
Bacterial pre rRNA transcript has ________________ |
A. | 23S 4S 16S 5S |
B. | 16S 4S 23S 5S |
C. | 16S 5S 23S |
D. | 23S 16S 5S |
Answer» C. 16S 5S 23S | |
14. |
Which of the following is not a normal modification of the rRNA primary transcript? |
A. | Conversion of U base to Pseudo uridine |
B. | Methylation of the 2’- OH region of specific rRNA bases |
C. | Cleavage of the intervening regions by exonucleases |
D. | Proteins modulating the cleavage |
Answer» E. | |
15. |
The cleavage of the rRNA is aided by the snRNA. |
A. | True |
B. | False |
Answer» C. | |
16. |
The primary transcript is ______________ |
A. | 52S |
B. | 45S |
C. | 32S |
D. | 17S |
Answer» C. 32S | |
17. |
The pre-rRNA transcript transcribed by the RNA pol Idoesn’t include_________$ |
A. | 18S |
B. | 5S |
C. | 5.8S |
D. | 28S |
Answer» C. 5.8S | |
18. |
tRNA constitutes ___________ % of all RNA. |
A. | 85 |
B. | 25 |
C. | 15 |
D. | <5 |
Answer» D. <5 | |
19. |
If you run the whole RNA extract on a gel you will get ____________ bands normally. |
A. | Many |
B. | One |
C. | Two |
D. | Three |
Answer» D. Three | |