MCQOPTIONS
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MCQOPTIONS
This section includes 17 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
All the RNA polymerases share 5 common subunits, which are present in all the three polymerases and are all alike. State whether the statement is true or false. |
| A. | True |
| B. | False |
| Answer» C. | |
| 2. |
How many of eukaryotic RNA polymerase subunits are common for all three polymerases? |
| A. | 3 |
| B. | 5 |
| C. | 10 |
| D. | 7 |
| Answer» C. 10 | |
| 3. |
RPA 2 is one of the larger subunits of RNA polymerase in eukaryotes. It is homologous to the prokaryotic _____________ |
| A. | Alpha subunit |
| B. | Beta subunit |
| C. | Beta prime subunit |
| D. | Omega subunit |
| Answer» C. Beta prime subunit | |
| 4. |
In an experiment you add growing concentration of the alpha amanitin. What will be the sequence in which RNA polymerases are affected if at all? |
| A. | Pol I -> pol III , pol II unaffected |
| B. | pol I->pol I ->pol III |
| C. | pol III->pol II -> pol I |
| D. | pol II -> pol III , pol I unaffected |
| Answer» E. | |
| 5. |
IN_AN_EXPERIMENT_YOU_ADD_GROWING_CONCENTRATION_OF_THE_ALPHA_AMANITIN._WHAT_WILL_BE_THE_SEQUENCE_IN_WHICH_RNA_POLYMERASES_ARE_AFFECTED_IF_AT_ALL??$ |
| A. | Pol I -> pol III , pol II unaffected |
| B. | pol I->pol I ->pol III |
| C. | pol III->pol II -> pol I |
| D. | pol II -> pol III , pol I unaffected |
| Answer» E. | |
| 6. |
How many of eukaryotic RNA polymerase subunits are common for all three polymerases?$ |
| A. | 3 |
| B. | 5 |
| C. | 10 |
| D. | 7 |
| Answer» C. 10 | |
| 7. |
RPA_2_is_one_of_the_larger_subunits_of_RNA_polymerase_in_eukaryotes._It_is_homologous_to_the_prokaryotic______________$ |
| A. | Alpha subunit |
| B. | Beta subunit |
| C. | Beta prime subunit |
| D. | Omega subunit |
| Answer» C. Beta prime subunit | |
| 8. |
In a Drosophila polytene chromosome just before molting you add green labelled antibody against unphosphhorylated RNA pol II CTD and red labelled antibody against phosphorylated RNA pol II CTD. These give fluorescence on adding the respective substrates. What will be the colour in gene 74 EF and 75 B? |
| A. | Red |
| B. | Green |
| C. | Yellow |
| D. | Magenta |
| Answer» B. Green | |
| 9. |
All_the_RNA_polymerases_share_5_common_subunits,_which_are_present_in_all_the_three_polymerases_and_are_all_alike._State_whether_the_statement_is_true_or_false. |
| A. | True |
| B. | False |
| Answer» C. | |
| 10. |
In what sequence are the serine residues in RNA pol II phosphorylated? |
| A. | 5->2->7 |
| B. | 2->5->7 |
| C. | 2->7->5 |
| D. | 7->2->5 |
| Answer» D. 7->2->5 | |
| 11. |
Which factor phosphorylates the serine residues in RNA pol II CTD? |
| A. | TFIIA |
| B. | TFIIB |
| C. | TFIIH |
| D. | TFIID |
| Answer» D. TFIID | |
| 12. |
If you consider a transcribing RNA pol II with a transcript as small as 30 bases, which serine residue in its CTD will be phosphorylated? |
| A. | 2 |
| B. | 5 |
| C. | 7 |
| D. | None |
| Answer» C. 7 | |
| 13. |
You designed an antibody against phosphorylated CTD of RNA polymerase II. Then you use a DNA fragment with lac operon and try to immunoprecipitate the RNA pol II. What will be the expected result? |
| A. | Moderate concentration of RNA pol II will precipitate |
| B. | RNA pol II that precipitated will be contaminated with pol III |
| C. | High amount of RNA pol II will precipitate |
| D. | No RNA pol II will precipitate |
| Answer» E. | |
| 14. |
What is the sequence of the heptad repeat of C terminal domain? |
| A. | TSPWSTT |
| B. | YSPTSGS |
| C. | YSPTSPS |
| D. | YSLPSTS |
| Answer» D. YSLPSTS | |
| 15. |
Which RNA polymerase can bind CBP? |
| A. | I |
| B. | II |
| C. | III |
| D. | None |
| Answer» C. III | |
| 16. |
You isolate the nucleolus from the nucleus and performed a density gradient centrifugation with the extract. Then you check the different for the RNA polymerase activity of the different segment. Which RNA polymerase would you expect to find in abundance? |
| A. | RNA pol I |
| B. | RNA pol II |
| C. | RNA pol III |
| D. | RNA pol IV |
| Answer» B. RNA pol II | |
| 17. |
Prokaryotes have 1 RNA polymerase. How many RNA polymerases are there in eukaryotes? |
| A. | 2 |
| B. | 3 |
| C. | 4 |
| D. | None |
| Answer» C. 4 | |