MCQOPTIONS
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MCQOPTIONS
This section includes 17 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
What is the molecule released in 2nd step of Alk B reaction which returns the base to normal form? |
| A. | Succinate |
| B. | Alpha ketoglutarate |
| C. | Formaldehyde |
| D. | O2 |
| Answer» D. O2 | |
| 2. |
It is good that Guanine methyl transferase is absent in human beings. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
You radiate a stock of E. Coli with UV rays and another stock is irradiated as control. The 1st stock is seen to be more resistant to alkylating agents. Which gene is expected to be triggered by this UV? |
| A. | AlK B |
| B. | Guanine methyl transferase |
| C. | MTHF poly Glu |
| D. | RUV |
| Answer» C. MTHF poly Glu | |
| 4. |
Which of the molecule in photolyase acts as an electron donor for recovery of the CPD? |
| A. | NADH |
| B. | FADH- |
| C. | MTHF poly Glu |
| D. | NAD+ |
| Answer» C. MTHF poly Glu | |
| 5. |
YOU_RADIATE_A_STOCK_OF_E._COLI_WITH_UV_RAYS_AND_ANOTHER_STOCK_IS_IRRADIATED_AS_CONTROL._THE_1ST_STOCK_IS_SEEN_TO_BE_MORE_RESISTANT_TO_ALKYLATING_AGENTS._WHICH_GENE_IS_EXPECTED_TO_BE_TRIGGERED_BY_THIS_UV??$ |
| A. | AlK B |
| B. | Guanine methyl transferase |
| C. | MTHF poly Glu |
| D. | RUV |
| Answer» C. MTHF poly Glu | |
| 6. |
WHICH_OF_THE_MOLECULE_IN_PHOTOLYASE_ACTS_AS_AN_ELECTRON_DONOR_FOR_RECOVERY_OF_THE_CPD??$ |
| A. | NADH |
| B. | FADH- |
| C. | MTHF poly Glu |
| D. | NAD+ |
| Answer» C. MTHF poly Glu | |
| 7. |
What is the molecule released in 2nd step of Alk B reaction which returns the base to normal form?$ |
| A. | Succinate |
| B. | Alpha ketoglutarate |
| C. | Formaldehyde |
| D. | O<sub>2</sub> |
| Answer» D. O<sub>2</sub> | |
| 8. |
It is good that Guanine methyl transferase is absent in human beings.$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 9. |
What is the prokaryotic homologue of XPC? |
| A. | RAD 51 |
| B. | RAD 10 |
| C. | RAD 23 |
| D. | RAD 50 |
| Answer» D. RAD 50 | |
| 10. |
Which of the factor in prokaryotic NER acts as the helicase? |
| A. | Urv A |
| B. | Ruv C |
| C. | TFIIH |
| D. | Uvr D |
| Answer» E. | |
| 11. |
Which of the factors are necessary in TC NER but not in GG NER? |
| A. | hHR23B |
| B. | ERCCI- XPF |
| C. | CSA |
| D. | RAD23 |
| Answer» D. RAD23 | |
| 12. |
What is the stretch of free DNA needed by NER machinery to repair the bulky lesions in TC NER? |
| A. | 50 nt |
| B. | 100 nt |
| C. | 200 nt |
| D. | 250 nt |
| Answer» B. 100 nt | |
| 13. |
Which of the DNA polymerase in eukaryotes is responsible for repair synthesis of the excised strand in NER? |
| A. | Pol epsilon |
| B. | Pol III |
| C. | Pol beta |
| D. | Pol I |
| Answer» B. Pol III | |
| 14. |
Which of the exonucleases of NER binds to which end of the lesion? |
| A. | XPD on 3’ end and XPB on 5’ end |
| B. | XPF on 3’ end and XPA on 5’ end |
| C. | XPG on 3’ end and XPF on 5’ end |
| D. | XPD on 3’ end and XPA on 5’ end |
| Answer» D. XPD on 3‚Äö√Ñ√∂‚àö√ë‚àö¬• end and XPA on 5‚Äö√Ñ√∂‚àö√ë‚àö¬• end | |
| 15. |
Which of the following NER factors is also a subunit of a transcription factor? |
| A. | XPA |
| B. | XPC |
| C. | XPF |
| D. | XPB |
| Answer» E. | |
| 16. |
The bulky lesions in GG-NER is detected by ___________ |
| A. | XPA |
| B. | XPD |
| C. | XPC |
| D. | XPG |
| Answer» D. XPG | |
| 17. |
In an experiment you fuse cells from two patients suffering from XP ( Xeroderma Pigmentosum). The fused cells will be expected to agree to which of the following? |
| A. | The resultant cells will have worsened case of XP |
| B. | Only one of the two NER defects that is dominant will be seen |
| C. | No XP defect in the resultant |
| D. | Both will show a similar effect of XP as before |
| Answer» D. Both will show a similar effect of XP as before | |